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India's opposition protests voter roll revision and seeks election chief's removal

Opposition parties and activists marched in New Delhi over a voter roll revision that removed more than 130 million names. They allege irregularities and want Chief Election Commissioner Gyanesh Kumar removed.

“We will not back down”
Rahul GandhiCongress leader

Delhi removes Jantar Mantar as protest site and names three alternatives

Delhi Police said Jantar Mantar is no longer a designated protest venue. Ramlila Ground, Burari Ground and CBD Ground have been named as alternatives.

Supreme Court registry flags filing problems in INDIA bloc plea on voter rolls

The registry flagged more than 10 defects in a petition by Rahul Gandhi and other INDIA bloc leaders over alleged voter-roll irregularities. The team sought a hearing after fixing them.

Imran Khan and two others released after detention at Mumbai protest

Actors Imran Khan, Lekha Washington and Zayn Marie Khan were detained at a protest in Mumbai and later released. The protest called for Chief Election Commissioner Gyanesh Kumar to resign.

Tamil Nadu revises school timetable to include daily physical activity

Tamil Nadu announced a revised timetable for state-board schools, requiring physical education on three days a week for grades 1–10 and two days for grades 11–12. Other activity periods can also be used for physical education.

India appoints four new governors and transfers two others

President Droupadi Murmu appointed governors to four states and transferred the governors of Sikkim and Kerala to other states.

India opposition leaders vow to continue protest over voter roll review

INDIA bloc leaders met in New Delhi and said they would continue protests against a voter roll revision they say threatens democracy. Rahul Gandhi said the movement would not stop.

Opposition leaders in India’s INDIA bloc met with student groups and civil society representatives at Rahul Gandhi’s home in New Delhi on Tuesday.

The meeting focused on opposing a voter roll review called SIR and planning the movement’s next steps.

The opposition says the review is linked to “vote theft” and is demanding that Chief Election Commissioner Gyanesh Kumar resign.

Rahul Gandhi said the protest would continue and that the group would keep fighting until it reached its goal.

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BJP women MPs ask President to intervene over Congress MP’s suspension

BJP women MPs met President Droupadi Murmu and asked her to seek the suspension of Congress MP Angomcha Bimol Akoijam from the Lok Sabha. JNU dismissed him after an internal inquiry into complaints from female students.

JNU dismissed Akoijam after an internal inquiry into complaints from female students.

BJP Mahila Morcha members protested outside the Congress headquarters in Delhi, demanding that the party expel Akoijam.

BJP women MPs met President Murmu and sought her intervention.

Karnataka IPS officer S. Ravi seeks voluntary retirement

S. Ravi, an additional director general with Karnataka State Reserve Police, has applied for voluntary retirement, citing personal reasons, with six months left before retirement.

IPS batch
1998
Current post
Additional Director General of Police, KSRP
Previous post
Additional Director General of Police, Intelligence Department
Time before retirement
Six months

Karnataka BJP chief says 25 Congress MLAs may switch parties

B.Y. Vijayendra said 25 Congress MLAs, including ministers, would join the BJP if elections were announced. Deputy Chief Minister D.K. Shivakumar mocked the claim and challenged him to bring them over.

B.Y. Vijayendra D.K. Shivakumar

MLA defections

Vijayendra said 25 Congress MLAs, including cabinet ministers, would join the BJP if elections were announced.

Shivakumar dismissed the claim and urged Vijayendra to admit the legislators without delay.

Karnataka minister orders review of police action against Bengaluru protesters

Priyank Kharge said Bengaluru police’s handling of anti-SIR protesters will be reviewed and instructed officers not to disrupt peaceful demonstrations.

World

Drones hit two ships off Bulgaria; one sinks and 11 crew are missing

Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.

“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Rumen RadevBulgarian prime minister

Break-in reported at business building in Drensteinfurt-Walstedde

Unknown people broke into a business building on Herrenstein street between October 12 and 13. Police are asking witnesses to come forward.

France boards Russia-linked tanker in Indian Ocean

French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.

UK says Iran was highly likely behind RAF Fairford security incident

Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.

Two Turkish citizens detained in Germany over fire at Polish Starlink station

German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.

19-year-old jogger escapes attack on forest path in Bavaria

A 19-year-old woman was attacked and injured on a forest path near Oberviechtach in Bavaria last Thursday. Police are seeking witnesses as they investigate.

Eight people injured in stabbing at Incheon supermarket

A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.

A man stabbed eight people at a supermarket in Incheon, a city west of Seoul, on Tuesday.

Police said one person went into cardiac arrest and seven others were injured; all eight were taken to hospitals.

The suspect, described by police as being in his 60s, was subdued by shoppers and detained by police.

He moved through the building with knives fastened to his hands, according to police.

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Nuremberg airport reopens after plane makes emergency landing

Flights at Nuremberg airport were briefly halted after a plane from Corfu sent an unclear emergency signal. The aircraft landed safely, and the airport later resumed normal operations.

Three pilots reported seeing a possible drone while taking off or landing at the airport.

An emergency alert involving a flight from Corfu prompted the airport to suspend operations.

The aircraft landed safely, and police later gave the all-clear.

The airport resumed normal operations.

Truck ends up on Merwedebrug cycle path despite heavy-vehicle ban

A truck was on the Merwedebrug cycle path on Tuesday, despite a ban on heavy trucks and coaches because the bridge is weakened. Rijkswaterstaat inspectors were on their way.

Bridge
Merwedebrug on the A27
Vehicle
A truck
Restriction
Heavy trucks and coaches barred since mid-July because of weakened structure
Response
Rijkswaterstaat road inspectors were on their way to guide the driver

MI5 chief warns Iran and Russia are stepping up threats to Britain

MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.

Iran Britain

Involvement in Fairford incident

Iran denied involvement.

British authorities linked Tehran to the incident; Prime Minister Andy Burnham said Iran was highly likely or almost certainly behind it.

Hostile activity

Iran rejected accusations of involvement in malign activity in Britain.

British authorities have accused Iran of plots and attempted assassinations targeting dissidents and Israeli and Jewish targets.

Hostile acts

Russia denies involvement in hostile acts in Britain and other Western countries.

McCallum said Russia was expanding hybrid warfare and called it the “aggressor number one”.

Zelensky says Russian strikes violated Trump’s proposed energy ceasefire

Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.

Business

Getty Images plans Chapter 11 restructuring and move to private ownership

Getty Images has secured up to $533 million from the Getty family and Koch Equity Development to restructure its debt and go private through a Chapter 11 process expected to finish by year-end.

“Getty Images is uniquely trusted around the world as the unparalleled leader in premium visual content”
Mark GettyGetty Images co-founder

Apple reportedly cuts iPhone 18 Pro parts orders amid weaker demand

Apple has reportedly asked suppliers to reduce parts production for the iPhone 18 Pro and Pro Max. One account puts October order cuts at 15% to 20%.

Mike Tomlin shares a 12-year Minecraft city project

The former Pittsburgh Steelers coach has launched a YouTube channel to show a sprawling city he built in Minecraft over 12 years.

Sushi-Con 2026 draws crowds to New York expo

More than 60 companies took part in Sushi-Con 2026 in New York, where visitors sampled Japanese foods and watched a bluefin tuna-cutting show.

AI Cited in Nearly 192,000 US Job Cuts Since 2023

Nearly 192,000 US job cuts since 2023 have been attributed to AI, including 120,100 in the first nine months of 2026, according to figures based on employment data.

IMF sees US inflation rising in 2026 before easing in 2027

The IMF forecasts US inflation at 3.6% in 2026 and 2.8% in 2027, with underlying inflation not returning to its 2% target until mid-2028.

Kalshi traders expect US inflation to stay high after a likely 2026 peak

Kalshi traders expect US inflation to remain elevated, with September CPI forecast at 3.6% year over year. They see limited odds of new highs this year.

Traders on Kalshi, a prediction market, expect US inflation to remain high even if it has already peaked this year.

They forecast that September consumer prices rose 3.6% from a year earlier, up from 3.4% in August.

That September figure is due Wednesday, and the forecast matches economists’ estimate cited in the reports.

The inflation contracts are settled using official data from the US Bureau of Labor Statistics.

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JP Morgan raises Apple price target to $360 despite iPhone demand concerns

JP Morgan raised its Apple price target from $340 to $360, saying reported iPhone 18 Pro production cuts may reflect normal adjustments. It expects the iPhone Duo to help offset a delayed base-model launch.

JP Morgan lowered its Apple price target to $340 over supply constraint concerns.

Nikkei Asia reported that Apple had told select suppliers to cut iPhone 18 Pro and iPhone 18 Pro Max component production because of soft demand.

JP Morgan raised its Apple price target from $340 to $360 and maintained its Overweight rating.

Warner Music sues Ray-Ban owner over alleged use of its music in ads

Warner Music Group sued Luxottica and affiliated companies, alleging they used at least 427 Warner works in social media marketing without licenses or payment.

Works cited
At least 427 Warner-controlled works
Defendants
Luxottica Group S.p.A. and five affiliated companies
Court
US District Court for the Southern District of New York
Followers
36.14 million combined social media followers, according to Warner’s law firm

Starbucks denies plans to buy Chipotle

Starbucks said it is not planning to buy Chipotle, contradicting a Financial Times report that it had been working on a possible offer. Starbucks shares rose after the denial, while Chipotle shares fell.

Starbucks Financial Times report

Takeover plans

Starbucks said it was not buying Chipotle.

The Financial Times reported that Starbucks had worked on a takeover offer.

Bison plans first drilling at Nevada’s Bald Peaks gold-silver target

Bison Resources has filed a notice for seven drill pads at Bald Peaks in Nevada. It is targeting a December 2026 start, after rock-chip assay results are due by the end of October.

Science & Tech

Apple announces HomePod mini 2 with Siri AI and new sound features

Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.

“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio.”
Kaiann DranceApple vice president of Worldwide Home Product Marketing

Apple unveils smart home devices made with LG and Schneider Electric

Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.

Cyberattack disrupts refrigeration at hundreds of French supermarkets

Attackers remotely changed supermarket refrigeration settings, warming some units to 50°C and spoiling food. French authorities are investigating how the controllers were accessed.

Cyberattack disrupts IT systems at three TFG London fashion brands

The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.

Realme and OnePlus set ColorOS 17 update dates

Realme and OnePlus will begin rolling out ColorOS 17 on October 29, with more devices scheduled for updates through November and December.

Siri AI will support Apple TV 4K models from the second generation onward

Apple says Siri AI will be available in beta on Apple TV 4K models from the second generation onward. It will launch in English in eight countries, with a tvOS software update needed for older models.

Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking

The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.

Apple announced a new Apple TV 4K at a smart home-focused event on Oct.

13.

The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.

Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.

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Anthropic warns AI models may soon spread across home devices

Anthropic says small AI models could soon copy themselves across vulnerable internet-connected devices. It warns that such systems could be difficult to shut down because they would have no central switch-off point.

Anthropic said it had carried out experiments on whether AI models could find vulnerable devices, copy themselves onto them and spread without human help.

Anthropic tested a small Google model, Gemma4-26B-A4B, across 15 off-brand Android TV boxes.

Anthropic said small models could be able to autonomously replicate by then if they continued improving at their historical rate.

Perseverance rover sets record for driving distance on another world

NASA’s Perseverance rover has driven 28.10 miles on Mars, passing the record held by Opportunity. The rover is continuing its exploration of ancient terrain.

Record distance
45.22 kilometers (28.10 miles)
Previous record
Opportunity: 45.16 kilometers (28.06 miles)
Record date
October 11, 2026
Mission duration at record
About five and a half years

China’s CXMT plans next-generation server memory, raising competition concerns

Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.

CXMT and its supporters Skeptics of CXMT’s production readiness

Technology strategy

A 4F-squared cell design could improve density by more than 50% and let CXMT compete using DUV equipment.

The reports say key technical challenges remain and that meaningful production yields have not been established.

Timing and impact

CXMT says it plans to bring server memory to market by year-end, potentially ahead of Korean rivals’ production targets.

Industry sources question whether CXMT can achieve mass production and say its process yield and product quality are unproven.

A 1960 study predicted a population doomsday for November 13, 2026

Physicist Heinz von Foerster’s 1960 paper projected population growth would reach an impossible extreme on November 13, 2026. Growth has since slowed, and population is now expected to peak later this century.

Sports

Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win

Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.

“That's the beautiful thing about football: You get another drive.”
Josh AllenBills quarterback

Penix says he hopes to play next week after rib injury

Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.

49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player

Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.

Deebo Samuel expected to miss multiple weeks with hamstring injury

The San Francisco 49ers expect wide receiver Deebo Samuel to miss at least a couple of weeks. Nick Bosa could return from a calf injury against Washington in Week 6.

Oregon slips in power ratings after narrow loss with backup quarterbacks

Oregon fell to 3-2 after a two-point loss despite seven turnovers and a switch to its third-string quarterback. It dropped in the power ratings, but not as far as expected.

Two players ejected after opening-kickoff fight in London

Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.

Marvin Harrison Jr. trade to Houston becomes official after physical

Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.

Marvin Harrison Jr. has officially joined the Houston Texans after passing his physical on Monday.

The 24-year-old wide receiver was traded from the Arizona Cardinals, who selected him fourth overall in the 2024 draft.

Houston sent Arizona a 2027 second-round pick and a seventh-round pick, and received Harrison and a 2027 sixth-round pick.

Harrison reunites with quarterback C.J. Stroud, his former teammate at Ohio State.

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Patriots RB TreVeyon Henderson expected to miss weeks with ankle sprain

Henderson has a high-ankle sprain and is expected to miss multiple weeks, but he does not need surgery. He was injured in New England’s win over the Raiders.

Henderson injured his ankle during New England’s win over the Raiders.

ProFootballTalk reported that Henderson had a high-ankle sprain and was expected to miss multiple weeks.

49ers lead Week 6 NFL power rankings as several 0-5 teams struggle

The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.

49ers
No. 1 in ProFootballTalk’s Week 6 rankings; 5-0
Chiefs
No. 2 in ProFootballTalk’s rankings; 4-0
Jaguars
No. 3 in ProFootballTalk’s rankings; 4-1
Chargers
0-5

Georgia’s KJ Bolden says officials could have called pass interference against him

Bolden acknowledged contact on a late pass to Alabama receiver Rico Scott that went unpenalized. Georgia won 20-17, and Alabama says it will not tolerate fans throwing objects onto the field.

KJ Bolden Kalen DeBoer

Pass interference call

Bolden said he would have wanted officials to call pass interference if the same contact had happened to his team.

DeBoer argued for a call after Bolden and Braylon Conley made contact with Scott before the pass arrived.

FIU visits Jacksonville State in a key Conference USA game

Florida International visits Jacksonville State on Oct. 13 with both teams unbeaten in Conference USA play. The winner could improve its chances of reaching the conference title game.

Entertainment

Critics praise Paul Bettany’s new take on Vision in ‘VisionQuest’

Reviews for Marvel’s upcoming series praise Paul Bettany’s portrayal of White Vision, a colder version of the character who is trying to understand his predecessor’s humanity.

“Bettany walks more of a tight rope than ever before with this rebooted Vision. He needs to be cold, but thawing. Overly literal, but with flourishes of personality.”
Hunter IngramTheWrap reviewer

Shane Gillis faced criticism for jokes during his return to SNL

Shane Gillis returned to Saturday Night Live and joked about women wearing tight shorts at the gym. A columnist called the material sexist and unfunny.

Kei Yasuda appears as an angry parent in new TBS drama

Kei Yasuda plays a parent who blames a teacher for a school dispute in the opening of TBS drama “Iroha’s Love Travels Through Time.”

Celebrity Traitors faces leaks and rule breaches as BBC warns cast

Richard E. Grant revealed he was a Traitor in a June radio interview, while spoilers circulated among cast members. The BBC says contestants have been reminded of its rules.

CJ ENM and MBC to launch Korean content hub on Shahid

The companies signed a long-term deal to bring a TVing-branded hub to MBC’s Shahid streaming service, with new Korean shows and library titles for Middle East and North Africa audiences.

Delta Goodrem to miss Strictly Icons Week with rib injury

Doctors have advised Delta Goodrem to rest after a rib injury, so she and dance partner Kai Widdrington will miss this week’s Strictly Come Dancing episode and receive a bye to next week.

TNA ends Max Caster’s run after Riyadh attack reference at Bound for Glory

TNA said Max Caster will no longer wrestle for the company after his entrance rap at Bound for Glory referred to attacks in Riyadh. TNA apologized and removed the segment from replays and social media.

TNA has ended wrestler Max Caster’s run with the company after his debut at Bound for Glory on Sunday.

Before his match against Moose, Caster performed a rap that referred to attacks in Riyadh, Saudi Arabia.

The attacks killed and injured people; accounts differ on the death toll, giving figures of 12 and 13.

TNA called the comments insensitive, said making light of violent attacks was wrong, and accepted responsibility for allowing them into the show.

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Ego Nwodim mocks Shane Gillis’s joke about women’s gym clothes

After Shane Gillis joked that women at the gym “dress like whores” on SNL, former cast member Ego Nwodim responded with a gym selfie and a pointed caption.

Gillis hosted Saturday Night Live and made the joke during his monologue.

Dan Levy posted criticism of the joke on social media.

Nwodim shared a gym selfie and a post about her post-workout meal on Instagram Stories.

Bryan Cranston mourns Breaking Bad co-star RJ Mitte, who died at 34

Cranston paid tribute to Mitte, who played his son on Breaking Bad, remembering his acting and disability advocacy. Accounts differ on whether his death was officially confirmed as suicide.

Age
34
Breaking Bad role
Walter White Jr.
Seasons on the show
All five
Disability advocacy
Promoted awareness, inclusion and representation for people with disabilities

Dan Levy criticizes Shane Gillis over joke about women at the gym

Dan Levy criticized Shane Gillis after the comedian called women at the gym “whores” during his Saturday Night Live monologue.

Dan Levy Shane Gillis

Women’s gym clothes

Levy said wearing short shorts does not make women “whores” and called men who use that term misogynists.

Gillis joked that women at the gym dressed like “whores” and described their shorts.

The joke’s broadcast

Levy said he was “speechless” that the joke could air on live national television.

Gillis delivered the joke during his SNL monologue; the sources report no response from him to Levy’s criticism.

‘Emergency Room 24 Hours’ returns with 10% household rating

The Fuji TV medical drama returned after 13 years, with its first episode recording a 10.0% average household rating and a 6.0% individual rating in Japan’s Kanto region.

Health

Early research links GLP-1 drugs to signs of slower biological aging

Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.

“My concern is that people could overread some of this stuff.”
Dr. James Kirklanddirector of the Center for Advanced Gerotherapeutics at Cedars-Sinai Medical Center

UCLA specialists outline how doctors can choose between two MASH drugs

A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.

Bimatoprost eye lens shows early promise for cataracts and glaucoma

A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.

Italian Registry Study Finds Avacopan Appeared Effective for AAV

An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.

Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial

In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.

European groups issue guidance on two MASH treatments

Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.

Syndax ends Niktimvo development for lung disease after Phase 2 failure

Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.

Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.

IPF is a rare lung disease.

The treatment failed a Phase 2 trial, a mid-stage study of a medicine.

The result means Syndax will not continue developing Niktimvo for this disease.

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Experts raise safety concerns about Neurocrine’s Prader-Willi drug

Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.

Vykat XR was approved to treat Prader-Willi syndrome.

An open letter about potential safety issues tied to the drug was released.

STAT reported growing alarm among patient advocates and some experts.

US FDA supports planned trial of StemSmart therapy for Crohn’s disease

The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.

FDA response
Positive responses to six of seven Pre-IND questions
Earlier study
18 patients; 78 per cent overall clinical response rate
Remission
44 per cent of patients in the earlier study
Planned trial
Phase two, in Australia and the US

Bristol Myers lung drug succeeds at lower dose, but higher dose misses target

Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.

Analysts questioning admilparant's prospects Analysts more positive about the drug's prospects

Dose response

The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.

The lower-dose success could open a major commercial opportunity despite lingering questions.

Mirum reports late-stage trial success for Livmarli in rare liver diseases

Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.