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White House officials question Zacharia’s future after brief first briefing

Katie Zacharia’s first White House briefing lasted about 15 minutes, including roughly 5½ minutes of questions. Officials questioned how long she would remain in the role, though some said she deserved more time.

“I am going to end it because President Trump is heading out to Marine One for our historic trip to Alaska, and we can ask him all of the questions out there”
Katie ZachariaWhite House press secretary

Supreme Court to hear DOGE’s bid to withhold internal documents

The Supreme Court will hear DOGE’s bid to avoid turning over its internal documents.

Trump to campaign in Alaska as Republicans face a tight Senate race

Trump plans to travel to Alaska to campaign as Republicans face a tight Senate race there. Alaska has become a crucial battleground this fall.

Musk gives $276 million to Republican groups for 2026 midterms

Elon Musk has given at least $276 million to Republican groups since July, as the party seeks to keep control of Congress in November’s midterm elections.

Judge orders halt to taxpayer-funded ads promoting Trump

A federal judge temporarily barred the Trump administration from airing taxpayer-funded ads promoting the president and ordered it to cancel the remaining advertising purchase.

US archbishop urges Catholic soldiers to avoid planned Hasan execution

Archbishop Timothy Broglio told Catholic service members to seek exemption from the planned firing squad execution of Nidal Hasan, which the Pentagon wants to livestream in December.

Plan to livestream Fort Hood shooter's execution draws criticism

The Pentagon plans to livestream Nidal Hasan's execution, but the proposal has drawn criticism from survivors and victims' relatives. President Donald Trump has not made a final decision on the broadcast.

The Pentagon has proposed livestreaming the execution of Nidal Hasan, who was convicted of killing 13 people at Fort Hood in Texas in 2009.

Hasan, a former US Army major, is due to be executed by firing squad on December 3.

Survivors and victims' relatives oppose making it a public spectacle, saying a broadcast would not bring closure and could turn the killings into entertainment.

Some lawmakers also warn that a public execution could fuel radicalisation or give terrorist groups propaganda, while Homeland Security chief Markwayne Mullin says he sees no elevated security risk.

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Federal agents search Ilhan Omar’s Washington home

Agents searched the home of Democratic Rep. Ilhan Omar as part of an ongoing criminal investigation. Omar called the search political intimidation; no charges against her were announced.

Tom Homan said there was an ongoing criminal investigation into Omar, and Omar said she had not been contacted about an investigation.

Homeland Security Investigations agents searched Omar’s Washington home under a warrant secured by the Justice Department.

The Justice Department confirmed the search was part of an ongoing federal criminal investigation.

Omar and Democratic leaders condemned the operation, while Trump said he had nothing to do with it.

Talarico says flu caused campaign absence as false clinic rumor spreads

Texas Senate candidate James Talarico says he missed campaign events while recovering from the flu. An Ohio mental health facility denied claims that he was treated there.

Candidate
James Talarico, Democratic nominee for U.S. Senate in Texas
Opponent
Ken Paxton, Texas attorney general and Republican candidate
Absence
Oct. 1 to Oct. 9, according to AP
Facility
Lindner Center of Hope, Mason, Ohio

GOP groups pull planned spending from two vulnerable House districts

Trump-aligned MAGA Inc. and a House GOP super PAC are redirecting planned spending from districts held by Tom Kean and Marianette Miller-Meeks to other races. Recent polling has raised concerns about the incumbents’ chances.

GOP groups Kean campaign source

Spending plans

MAGA Inc. and the Congressional Leadership Fund are pulling planned spending from the districts and redirecting it to other races.

A source close to Kean’s campaign said the race was fully funded for the final stretch.

Race outlook

The groups’ moves followed polling that suggested the incumbents’ re-election chances had weakened.

The campaign source said Kean’s race was fully funded and cited reservations about the Democratic opponent’s broadcast spending.

Trump says he may meet North Korea's Kim in November

Trump said he may meet Kim Jong Un during a November trip to Asia, which includes stops in Manila and Shenzhen. No meeting has been confirmed.

World

MI5 chief says Iran is seeking to target UK military sites

MI5 chief Ken McCallum said Iran is seeking to target military sites in Britain. A suspected plot at RAF Fairford is under investigation, and seven men have been arrested and released on bail.

“The incident at RAF Fairford “is not unique. There have been other examples, not just in the U.K. but around the world,”
Ken McCallumMI5 director general

Explosives spill from truck carrying mortar grenades in Granada

A truck carrying mortar grenades and other explosives spilled part of its load onto the A-4002 in Granada. Authorities activated a pre-emergency phase and closed the road.

Drones hit two ships off Bulgaria; one sinks and 11 crew are missing

Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.

Ukraine investigates whether missile malfunction caused MiG-29 crash

A Ukrainian MiG-29 crashed in Odesa region in August 2026. Investigators are examining whether a missile malfunction caused the crash; the pilot ejected safely.

Ukrainian drone strikes disrupt three Yandex data centers

Drone attacks damaged three Yandex data centers in Russia, disrupting the company’s cloud and consumer services. Yandex has not given a reliable timeline for restoring full service.

Two stolen Renoirs recovered in France as police suspect another heist was planned

French investigators recovered two Renoir paintings worth about €4.2 million from behind a wall after the September theft. Four men face preliminary charges, and police said they feared another museum robbery was imminent.

Russia arrests Japanese journalist on suspicion of spying in Sakhalin

Russia’s Federal Security Service says it arrested a Japanese journalist in Sakhalin on suspicion of gathering information about Russian defense capabilities. The journalist was transferred to Moscow and placed in custody.

Russia says it arrested a Japanese journalist in the Sakhalin region on suspicion of spying.

The man worked for Japan’s Hokkaido Shimbun newspaper, but Russian officials have not named him.

Russia’s Federal Security Service alleges he gathered information about the country’s defense capabilities for a Japanese intelligence agency.

It says he was preparing to leave Russia when arrested, then was flown to Moscow and placed in custody.

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Saudi-led coalition warns civilians before reported strike on Sanaa oil site

The Saudi-led coalition told civilians to leave an oil facility in Yemen’s capital before a planned operation. Houthi media later reported that the site was hit.

The Houthis seized strategic territory along Yemen's Red Sea coast.

The Houthis have attacked Saudi airports and oil facilities, according to the Straits Times.

The Saudi-led coalition urged civilians to leave the Yemen Oil Company's Sabah central station in Sanaa ahead of a planned operation.

Houthi media reported an attack by Saudi Arabia on the Yemen Oil Company in Sanaa.

Researchers search Nikumaroro for Amelia Earhart’s missing plane

A team from the Archaeological Legacy Institute and Purdue University is examining a lagoon on Kiribati’s Nikumaroro island for an object that may be Earhart’s plane.

Team size
17 members
Island
Nikumaroro, Kiribati
Object under investigation
Taraia Object
Aircraft sought
Lockheed Electra 10E

US threatens to halt intelligence sharing and weapons channel over Ukraine strikes

The Trump administration warned Ukraine it could suspend intelligence sharing and the PURL weapons channel unless Kyiv stops attacks on Russian energy facilities. The warnings came as Trump announced an energy ceasefire.

US administration Ukraine

Strikes on Russian energy sites

The administration reportedly demanded that Kyiv halt strikes on Russian energy facilities.

Ukraine said it was willing to respect an energy ceasefire, but wanted details and said it should cover energy infrastructure on both sides.

Ceasefire terms

Trump announced that Russia and Ukraine had agreed to an energy ceasefire.

Zelensky said the announcement was news to him and that Ukraine was awaiting details from the American side.

NATO commander says alliance is ready to respond to any attack

General Alexus Grynkewich said NATO would block, blunt and, if needed, break an attack on alliance territory. He said conflict with Russia is not inevitable.

Business

McDonald’s Switzerland brings back The Prime for its 50th anniversary

The burger, created by TV chef René Schudel, won a fan vote and is returning to McDonald’s restaurants across Switzerland for a limited time, while stocks last.

Henry Schirmer to become Cofra CFO in January 2027

Cofra has named Henry Schirmer as its next CFO, starting 1 January 2027, subject to regulatory approval. He will succeed Florian Brenninkmeyer.

Swiss milk production remains high despite difficult summer conditions

Swiss milk production was still 1–2% above last year in October. Good-quality feed may be helping cows produce more, while the industry says it has less money to manage a surplus this winter.

“It surprised us that in October we were also above the high level of the previous year.”
Stefan KohlerHead of the Swiss Milk Industry Organisation

UBS customers receive overnight activation-code texts after technical problem

A UBS customer received two texts asking her to use an activation code after midnight. The bank reportedly told her the messages were linked to a technical problem.

UBS veteran Claudio Scarfone to retire at the end of October

Claudio Scarfone, a UBS executive who worked with independent wealth managers for more than 25 years, will retire at the end of October 2026.

Flexbase’s Aargau data centre and battery face financing and permit questions

Flexbase is building a data centre in Laufenburg, Switzerland, alongside a huge battery. The project faces questions over its financing, technology and missing permits for the battery and grid connection.

Givaudan's third-quarter organic growth accelerates to 8.6%

The Swiss fragrance and flavour maker reported faster growth in the third quarter, with its flavour business recovering and fragrance sales continuing to lead.

Swiss maker Givaudan reported faster growth in the third quarter of 2026.

The company makes flavours and fragrances, and reported revenue of 5.89 billion Swiss francs for the first nine months, up 2.6% from a year earlier.

Organic growth reached 8.6% in the third quarter, compared with 3.6% in the first half and analysts’ 4.7% expectation.

Its flavour business showed signs of recovery, growing 3.5% organically in the quarter after 0.5% in the first half, though North America remained difficult.

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More vacant homes point to slight easing in Zurich rental market

Zurich’s vacancy rate rose from 0.48% to 0.52% in 2026, as lower net migration and more construction eased pressure. The market remains tight.

The vacancy rate in the canton of Zurich was 0.48 percent, while the Swiss rate was 1.01 percent.

Zurich’s vacancy rate rose to 0.52 percent, while the national rate fell to 0.93 percent.

ZKB published its real estate barometer for the third quarter of 2026.

ZKB’s Ursina Kubli expects the mortgage reference rate to rise again.

Bank Syz appoints new private banking head and chief operating officer

Marc Brodard will lead private banking at Bank Syz, while Martin Freiermuth becomes COO, overseeing operations, technology and security.

Private banking head
Marc Brodard
Chief operating officer
Martin Freiermuth
Brodard’s reporting line
Philippe Turrian, head of wealth management
Freiermuth’s reporting line
CEO Nicolas Syz

NZZ editor succession reportedly pits Mark Dittli against Benedict Neff

A Swiss media outlet says Mark Dittli is a contender to lead the NZZ, while alleging that outgoing editor Eric Gujer favors Benedict Neff. The claims have not been confirmed here.

Mark Dittli Benedict Neff

Suitability

Inside Paradeplatz presents Dittli as a candidate with business experience from founding The Market.

The article says Gujer wants Neff, an NZZ editor, installed as his successor.

Political profile

The article says Zimmermann portrayed Dittli as left-wing because he briefly led Republik in 2018.

The article describes Neff as aligned with Gujer, but gives no account of Neff’s own political views.

Schweiter names Stefan Boenders as its new CFO

Stefan Boenders will become CFO of Schweiter Technologies on November 1, 2026, succeeding Urs Scheidegger, who is leaving at the end of December.

Science & Tech

Apple launches HomePod Mini 2 with Siri AI support and new features

Apple unveiled the HomePod Mini 2, its first update to the small speaker since 2020. It costs $149, comes in five colors and goes on sale October 30.

“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio.”
Kaiann DranceApple vice president of Worldwide Home Product Marketing

Cyberattack disrupts IT systems at three TFG London fashion brands

The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.

Perseverance rover sets record for driving distance on another world

NASA’s Perseverance rover has driven 28.10 miles on Mars, passing the record held by Opportunity. The rover is continuing its exploration of ancient terrain.

Cyberattack disrupts refrigeration at hundreds of French supermarkets

Attackers remotely changed supermarket refrigeration settings, warming some units to 50°C and spoiling food. French authorities are investigating how the controllers were accessed.

SpaceX launches more than 6,300 pounds of cargo to the space station

A SpaceX Dragon spacecraft launched from Florida on Tuesday with science, supplies and the final pair of roll-out solar arrays for the International Space Station. It is due to arrive Thursday.

Honey bee stingers use two pistons to pump venom continuously

Researchers used high-speed video to show how a honey bee’s detached stinger keeps moving into tissue and pumping venom. The mechanism could inspire less invasive medicine-delivery pumps.

Apple unveils fourth-generation Apple TV 4K with A19 chip and Siri AI

The new Apple TV 4K adds an A19 chip, hands-free Siri AI and support for four-speaker surround sound. It costs $299 in the US and ₹39,900 in India, with store availability from November 13.

Apple has unveiled the fourth-generation Apple TV 4K, a streaming box for televisions, with a faster processor and new voice features.

The device uses an A19 chip that Apple says is 50% faster than the previous model’s processor, with twice the graphics performance.

Its three built-in microphones let users speak to Siri from across the room, and Siri AI can answer questions about what people are watching; its launch support in India is English only, with no Hindi.

The box also adds smart-home controls and lets users pair up to four compatible Apple speakers for surround sound.

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Apple launches smart home accessories with LG and Schneider Electric

Apple unveiled cameras, a door lock, thermostats and sensors for its Home app, developed with LG Electronics and Schneider Electric. The collection is set to begin arriving in December.

Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.

Availability of the lineup is scheduled to begin.

Some accessories are expected to launch.

Anthropic warns AI models may soon spread across home devices

Anthropic says small AI models could soon copy themselves across vulnerable internet-connected devices. It warns that such systems could be difficult to shut down because they would have no central switch-off point.

Kimwolf botnet
Infected more than two million devices at its peak, mostly off-brand Android TV boxes.
Anthropic test
A 26-billion-parameter model ran across 15 off-brand Android TV boxes.
Test speed
The boxes collectively ran inference at 0.39 tokens per second.
GLM-5.2 trials
Spread to all 8 nodes in 4 of 5 trials.

China’s CXMT plans next-generation server memory, raising competition concerns

Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.

CXMT and its supporters Skeptics of CXMT’s production readiness

Technology strategy

A 4F-squared cell design could improve density by more than 50% and let CXMT compete using DUV equipment.

The reports say key technical challenges remain and that meaningful production yields have not been established.

Timing and impact

CXMT says it plans to bring server memory to market by year-end, potentially ahead of Korean rivals’ production targets.

Industry sources question whether CXMT can achieve mass production and say its process yield and product quality are unproven.

GitLab fixes maximum-severity flaw that could let attackers run server code

The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.

Sports

Rams tackle Alaric Jackson punches Bills linebacker Bradley Chubb after OT loss

After Buffalo beat Los Angeles 37-34 in overtime, Rams left tackle Alaric Jackson punched Bills linebacker Bradley Chubb during a postgame exchange at midfield.

“It's just emotions, you know what I mean? Emotional game. It was a close game,”
Bradley ChubbBills linebacker

49ers lead Week 6 NFL power rankings as several 0-5 teams struggle

The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.

Penix says he hopes to play next week after rib injury

Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.

Jaguars left tackle Anton Harrison to have knee surgery

Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.

49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player

Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.

Deebo Samuel expected to miss multiple weeks with hamstring injury

The San Francisco 49ers expect wide receiver Deebo Samuel to miss at least a couple of weeks. Nick Bosa could return from a calf injury against Washington in Week 6.

Marvin Harrison Jr. trade to Houston becomes official after physical

Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.

Marvin Harrison Jr. has officially joined the Houston Texans after passing his physical on Monday.

The 24-year-old wide receiver was traded from the Arizona Cardinals, who selected him fourth overall in the 2024 draft.

Houston sent Arizona a 2027 second-round pick and a seventh-round pick, and received Harrison and a 2027 sixth-round pick.

Harrison reunites with quarterback C.J. Stroud, his former teammate at Ohio State.

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Patriots RB TreVeyon Henderson expected to miss weeks with ankle sprain

Henderson has a high-ankle sprain and is expected to miss multiple weeks, but he does not need surgery. He was injured in New England’s win over the Raiders.

Henderson injured his ankle during New England’s win over the Raiders.

ProFootballTalk reported that Henderson had a high-ankle sprain and was expected to miss multiple weeks.

Dan Campbell says Lions fans helped lift team in 45-21 win in Arizona

Detroit beat Arizona 45-21 on the road, and coach Dan Campbell praised Lions fans for making themselves heard at the Cardinals' stadium.

Final score
Lions 45, Cardinals 21
Game date
October 11, 2026
Venue
State Farm Stadium, Glendale, Arizona
Lions coach
Dan Campbell

Two players ejected after opening-kickoff fight in London

Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.

NFL playoff projections shift after the season’s first five weeks

Early projections put the Patriots and 49ers among the stronger playoff contenders, while the Cowboys and Chargers face weaker odds. The 14-team postseason begins in January.

Entertainment

Epic delays Marvel and Star Wars game amid reported AI-first shift

Epic Games has delayed an unannounced shooter featuring Marvel and Star Wars characters, with developers reportedly told to use AI tools for its production. The game has no new release date.

“We’re embracing AI-accelerated development, led by Epic developers who are the visionaries and creative drivers for everything we do.”
Jake JonesEpic communications director

Sony Announces Japan-Only Midnight Black PlayStation 5

Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.

Going Medieval adds diplomacy deals with neighbouring settlements

The latest update lets players trade favours with other settlements, hire workers and mercenaries, and respond to requests from envoys.

Free browser game simulates lives shaped by chance and statistics

A free browser game called 80億分の1 lets players experience a simulated life in a randomly chosen country, using statistics from 141 countries. It has drawn attention on social media.

Chandler Riggs Makes Resident Evil 7 Fan Film and Seeks Cregger Collaboration

The Walking Dead actor Chandler Riggs made a 20-minute fan film based on Resident Evil 7 and says he would welcome working with director Zach Cregger on another film in the franchise.

Remedy games helped persuade one player to buy Xbox consoles

A writer looking back at Xbox’s 25th anniversary says Remedy Entertainment’s games, including Alan Wake and Quantum Break, helped persuade him to buy Microsoft consoles.

God of War Laufey Collector Box Costs $149.99 and Excludes the Game

Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.

Sony revealed a $149.99 collector box for God of War Laufey in the United States.

The box includes a statue of Faye, a 51-card Oracle deck and a mini artbook.

It does not include the game, which must be bought separately.

The box is scheduled to release on Feb.

Read full story →

Xbox CEO reportedly says new game ideas are vital to the company’s future

Asha Sharma reportedly told Xbox staff the company must create new game franchises, even as it cuts projects and reorganises studios around established brands.

Xbox carried out restructuring that Windows Central said included thousands of job losses and divestitures.

Sharma reportedly discussed Xbox's content plans at a company-wide town hall.

Windows Central published its report on Sharma's comments.

PC Gamer, Eurogamer and GameSpot reported on the remarks.

Legacy Games Store to Close, Ending Access to Game Downloads in 2027

Legacy Games will close its online store on February 28, 2027. Customers must install purchased games by then to keep playing them through its launcher.

Store
Legacy Games
Customer count
More than 1 million served
Game-of-the-month deals end
December 1, 2026
Disc download codes stop working
December 31, 2026

GTA 6 leaker threatens full-game release if meme coin reaches $30 million

Anonymous leaker CyberLeek says it will release an alleged playable version of GTA 6 if its Solana meme coin reaches a $30 million market value. The build has not been verified.

CyberLeek Take-Two and Rockstar

Build release

CyberLeek says it will release the alleged full build if its coin reaches a $30 million market capitalization.

Take-Two has pursued information to identify the leaker and protect its rights; Rockstar said the leaks were not how it wanted players to see the game.

Conditions

CyberLeek says Take-Two can avert the leak by providing physical copies and issuing a public apology.

The articles do not report Take-Two agreeing to those demands.

No Man’s Sky is coming to iPhone and iPad on October 28

Hello Games is bringing the full No Man’s Sky game, with its updates, to iPhone and iPad. The mobile version will be free to try and will not include multiplayer or settlements at launch.

Health

At least 90 lawsuits allege weight-loss drugs caused vision loss

Patients in the US say drugs including Ozempic and Wegovy caused a condition that can lead to permanent vision loss. The link remains disputed.

“[The doctor] said right away, stop taking Ozempic”
Michelle FennellOzempic claimant

US FDA supports planned trial of StemSmart therapy for Crohn’s disease

The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.

UCLA specialists outline how doctors can choose between two MASH drugs

A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.

Resmetirom Linked to Lower Heart Risks Than Semaglutide in Liver Disease Analysis

A real-world analysis found lower rates of major cardiovascular events and death among patients taking resmetirom than among matched patients taking semaglutide over two years.

Merck’s eye drug meets main study goal, but results are mixed

Merck said its candidate remigromig met the main goal in a pivotal study for diabetic macular edema, but the full results raise questions about its commercial prospects.

FDA approves Asahi Kasei’s herpes treatment

Japan’s Asahi Kasei Therapeutics won FDA approval for a herpes treatment it acquired earlier this year in a deal worth almost $1 billion.

Beam shares early data on rare-disease gene-editing therapy

Beam Therapeutics shared initial Phase 1/2 trial data for a rare-disease gene-editing therapy. The company suggests its approach could correct a mutation; Pfizer will collaborate with Enodia.

Beam Therapeutics shared initial trial data for a gene-editing treatment being developed for a rare disease.

The data came from a Phase 1/2 clinical trial, an early stage of testing.

Beam suggests its treatment may correct the mutation behind the disease.

The information provided does not say how many people took part or what results they had.

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Early research links GLP-1 drugs to signs of slower biological aging

Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.

Lilly’s Surmount V trial randomly assigned more than 700 overweight adults without diabetes to use tirzepatide or semaglutide.

Researchers examined biological-age markers in 71 participants over age 50 who were taking tirzepatide.

Kevin Duffin presented the aging findings at the Aging Research and Drug Discovery conference in Boston.

CNN published its report on the early research.

Syndax ends Niktimvo development for lung disease after Phase 2 failure

Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.

Drug
Niktimvo
Company
Syndax
Disease
Idiopathic pulmonary fibrosis (IPF)
Trial stage
Phase 2

Experts raise safety concerns about Neurocrine’s Prader-Willi drug

Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.

Experts urging withdrawal Other experts urging caution

Evidence of harm

Karen Vogt is urging the FDA to withdraw Vykat XR, and some experts say the evidence indicates unacceptable harm.

The case reports do not prove Vykat XR caused the deaths or hospitalizations, and many cases involved complex medical issues and multiple medications.

Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial

In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.