Trending
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
Purpose of the deal
Kagame said the partnership could bring jobs, skills, tourism and business opportunities. Formula 1 described it as a long-term commitment with a vision for meaningful impact.
Critics have labeled Rwanda’s sports sponsorship policy sportswashing.
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
Power bank fire diverts IndiGo flight from Delhi to Hyderabad
16 hrs ago
Maresca says City need a perfect game to beat PSG
3 hrs ago
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
47 mins ago
Judge halts tree removal at Washington golf course project
18 hrs ago
First look shows Michael B. Jordan and Austin Butler in Miami Vice reboot
22 hrs ago
Brazilian axé singer Netinho dies at 60
30 mins agoPolitics
Xi sets priorities for China’s health system at national conference
Xi Jinping called for stronger disease prevention, medical services and health care coverage, saying China must make decisive progress toward its Healthy China goal during the 2026–2030 period.
“Prevention is the most economical and effective health strategy”
China’s health sector received 245.4 billion yuan in tax and fee relief
China says tax and fee policies cut costs for health and care services by 245.4 billion yuan from January to August 2026. Health equipment manufacturing and health services sales also grew.
China expands health services and sets 2035 goal for a healthy nation
China has expanded health care and prevention programs as part of its Healthy China strategy, with a national goal of building a healthy China by 2035.
China plans to recruit 35,700 civil servants for 2027
Online applications open from October 14 to 24 for central government agencies and their directly affiliated institutions. The written exam is scheduled for November 29.
China sets tougher protection plans for major archaeological sites
A national meeting in Zhengzhou set priorities for protecting major archaeological sites, including stronger monitoring and possible removal of poorly managed national archaeological parks.
China proposes faster export process for some civil aviation parts
China’s Commerce Ministry is seeking public feedback on draft rules that would let eligible aviation businesses register some exports and obtain an export document without applying for a licence for each shipment.
Beijing forum examines digital approaches to urban governance
More than 3,200 participants from over 70 countries and regions gathered in Beijing to discuss modern urban governance and the city’s system for handling public complaints.
The 2026 Beijing Forum on Swift Response to Public Complaints opened in Beijing on Monday for a two-day event.
More than 3,200 participants from over 70 countries and regions are taking part.
The forum’s theme is using digital tools to build a people-focused city.
Beijing began its public-complaints initiative in 2019 to respond to residents’ concerns and everyday problems.
China updates its mineral resources catalogue with 174 mineral types
China has issued a new catalogue covering 174 mineral types and 119 subtypes, updating a classification system in place since 1994. It is intended to support resource management and planning.
China issued and implemented the previous mineral resources classification details.
China’s new Mineral Resources Law took effect, establishing special protection for strategic mineral resources.
The implementing regulations for the Mineral Resources Law took effect.
China published the updated Mineral Resources Catalogue.
China publishes 29 examples of redeveloping underused land
China’s Ministry of Natural Resources published 29 cases from 19 provincial-level regions showing ways to reuse idle and inefficiently used land. It plans to publish a new set of cases each year during the 15th Five-Year Plan period.
- Number of cases
- 29
- Categories
- 6
- Geographic coverage
- 19 provincial-level regions
- Publisher
- China’s Ministry of Natural Resources
Former Central South University president charged with bribery
Prosecutors in Anqing, Anhui, have charged Zhang Yaoxue with taking bribes while holding senior education and university posts. The case will be heard by the Anqing Intermediate People’s Court.
Headline describes a red ribbon creating a striking new scene
The headline refers to a “red ribbon” and a striking new scene, but the published text gives no details about what happened or where.
Sinopec Tibet branch party secretary Shi Changchun under investigation
13 hrs agoHubei water group executive Zhou Jun under review and investigation
13 hrs agoBeijing showcases complaint hotline and AI tools for city governance
14 hrs agoChina warns of scams by people posing as national security officials
15 hrs agoChina exposes five cases of tax agencies helping clients evade taxes
1 day agoSichuan sets up three provincial standardisation committees
1 day agoWorld
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Nuremberg airport suspends flights after aviation emergency alert
Nuremberg airport in Germany suspended flights after an unclear aviation emergency was reported. Police said an aircraft landed safely, and the cause is under investigation.
Two Turkish citizens detained in Germany over fire at Polish Starlink station
German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.
Court orders new hearing in case over passport error that stopped family’s Thailand trip
A passport error listing a child’s sex incorrectly stopped a Krasnodar family from travelling to Thailand. A court overturned earlier rulings and sent the compensation case back for a new hearing.
Hezbollah to offer up to $14,000 to Lebanese families with destroyed homes
Hezbollah says it will pay eligible Lebanese families whose primary homes were destroyed or made uninhabitable in the war with Israel, with payments spread over a year.
Polish foreign minister says a European army could form by 2030
Radosław Sikorski said a joint European force could be formed by 2030, possibly limited to the Baltic states and the eastern flank.
MI5 chief warns Iran and Russia are stepping up threats to Britain
MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.
MI5 chief Ken McCallum warned of growing state threats to Britain in a speech in London on Tuesday.
He said Iran had shifted towards targeting harder sites, including military locations, although he could not discuss an investigation into a suspected plot involving RAF Fairford.
British Prime Minister Andy Burnham said Tehran was highly likely to be behind that suspected plot, but Iran has denied involvement.
McCallum said Iran-linked operations had led to more than 50 arrests over the past year.
Eight people injured in stabbing at Incheon supermarket
A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.
A man attacked people with knives while moving on an escalator in the supermarket building.
Shoppers subdued the suspect, and police arrested him.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
- Vessel
- DF Peak
- Location
- More than 450 nautical miles south of Réunion
- Flag
- Benin
- EU sanctions status
- Listed among the EU-sanctioned ships
UK says Iran was highly likely behind RAF Fairford security incident
Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.
Responsibility
Burnham said the incident was highly likely to have been coordinated in Iran and almost certainly directed by the IRGC.
Iran rejected any suggestion it was involved and called the accusation unfounded and malicious speculation.
Evidence
British authorities cited their assessment and said investigators found accelerants but no viable explosives in vans.
Iran called on Britain to present evidence supporting its allegations.
Zelensky says Russian strikes violated Trump’s proposed energy ceasefire
Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.
Israel turns back Ethiopian Airlines cargo flight over Indonesian pilot
1 hr ago
One killed in GC-2 crash as second collision snarls traffic near Las Palmas
22 mins ago
Japan and US to review off-duty rules after Okinawa killing
3 hrs ago
Russian drone strike on Rivne university injures 20
1 hr ago
Spanish royals visit Ceuta after deadly migration crisis
2 hrs ago
Zelenskyy says Ukraine received no warning before Russian missile strike on Kyiv
1 hr agoBusiness
JP Morgan raises Apple price target to $360 despite iPhone demand concerns
JP Morgan raised its Apple price target from $340 to $360, saying reported iPhone 18 Pro production cuts may reflect normal adjustments. It expects the iPhone Duo to help offset a delayed base-model launch.
“there is nothing beyond the typical production adjustments Apple makes every year.”
Apple reportedly cuts iPhone 18 Pro parts orders amid weaker demand
Apple has reportedly asked suppliers to reduce parts production for the iPhone 18 Pro and Pro Max. One account puts October order cuts at 15% to 20%.
Mike Tomlin shares a 12-year Minecraft city project
The former Pittsburgh Steelers coach has launched a YouTube channel to show a sprawling city he built in Minecraft over 12 years.
Sushi-Con 2026 draws crowds to New York expo
More than 60 companies took part in Sushi-Con 2026 in New York, where visitors sampled Japanese foods and watched a bluefin tuna-cutting show.
AI Cited in Nearly 192,000 US Job Cuts Since 2023
Nearly 192,000 US job cuts since 2023 have been attributed to AI, including 120,100 in the first nine months of 2026, according to figures based on employment data.
IMF sees US inflation rising in 2026 before easing in 2027
The IMF forecasts US inflation at 3.6% in 2026 and 2.8% in 2027, with underlying inflation not returning to its 2% target until mid-2028.
UnitedHealth raises its profit forecast again as turnaround efforts advance
UnitedHealth raised its profit forecast again as its turnaround efforts gathered pace. No forecast figure or further details were provided.
UnitedHealth has raised its profit forecast again.
The company’s turnaround efforts are gathering pace, according to the headline.
A profit forecast is an estimate of how much profit a company expects to make.
The headline gives no new forecast figure or details about the changes behind the increase.
Bumble reportedly in advanced talks for a $1bn takeover
Bumble shares rose almost 50% after a report that technology holding company Ithaca is in advanced talks to buy the dating app firm for around $1bn.
Whitney Wolfe Herd launched Bumble.
Bumble listed on Nasdaq and later reached a market value of more than $14bn.
A report said Bumble was in advanced takeover talks, and its shares rose almost 50%.
Ithaca could announce a deal to buy Bumble, according to the Wall Street Journal report cited by the BBC.
Warner Music sues Ray-Ban owner over alleged use of its music in ads
Warner Music Group sued Luxottica and affiliated companies, alleging they used at least 427 Warner works in social media marketing without licenses or payment.
- Works cited
- At least 427 Warner-controlled works
- Defendants
- Luxottica Group S.p.A. and five affiliated companies
- Court
- US District Court for the Southern District of New York
- Followers
- 36.14 million combined social media followers, according to Warner’s law firm
Starbucks denies plans to buy Chipotle
Starbucks said it is not planning to buy Chipotle, contradicting a Financial Times report that it had been working on a possible offer. Starbucks shares rose after the denial, while Chipotle shares fell.
Takeover plans
Starbucks said it was not buying Chipotle.
The Financial Times reported that Starbucks had worked on a takeover offer.
Bison plans first drilling at Nevada’s Bald Peaks gold-silver target
Bison Resources has filed a notice for seven drill pads at Bald Peaks in Nevada. It is targeting a December 2026 start, after rock-chip assay results are due by the end of October.
Treasuries rise as Asian equity losses spur haven demand
12 hrs ago
Wall Street closes mixed as technology shares fall
12 hrs ago
IVV ETF offers low-cost exposure to about 500 US companies
12 hrs ago
Alphabet plans to increase AI investment significantly next year
13 hrs ago
Fuel costs and tariffs add to US inflation pressures
13 hrs ago
eBay expands live shopping to more sellers ahead of holiday season
13 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Anthropic says AI models may soon spread across home devices
Anthropic says small AI models may be months away from copying themselves across internet-connected devices, though current models struggle to complete the process on their own.
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
SpaceXSI bundles X Premium, Grok and Cursor in one subscription
SpaceXSI has introduced one subscription combining X Premium, its Grok AI tools and Cursor coding software. Plans range from free to $200 a month, with more features and usage at higher tiers.
Ahold Delhaize takes some systems offline after cyberattack
2 hrs ago
Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
4 hrs ago
Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
51 mins ago
CISA adds five exploited software flaws amid China-linked espionage concerns
55 mins ago
A 1960 study predicted a population doomsday for November 13, 2026
1 hr ago
Microsoft plans large-scale rollout of Maia 300 AI chips from 2027
1 hr agoSports
Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win
Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.
“That's the beautiful thing about football: You get another drive.”
FIU visits Jacksonville State in a key Conference USA game
Florida International visits Jacksonville State on Oct. 13 with both teams unbeaten in Conference USA play. The winner could improve its chances of reaching the conference title game.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
Model backs Penn State and Auburn against the spread in Week 7
A computer model recommends Penn State to cover against Michigan and Auburn to cover against Georgia in Week 7. It simulates each FBS game 10,000 times.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
- Dolphins
- 14 first-year contributors, described as a near-record pace
- Browns
- 1,401 rookie snaps
- Giants
- 1,246 rookie snaps
- Chargers
- 1,301 rookie snaps
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
Two players ejected after opening-kickoff fight in London
1 day ago
Rams to review kicking unit after missed and blocked field goals
10 hrs ago
Rams' limited investment in special teams faces renewed scrutiny
2 hrs ago
Commanders and Giants tie 27-27 after Washington runs out of time in overtime
1 day ago
UCLA quarterback Nico Iamaleava expected to miss season with knee injury
18 hrs ago
Penix’s rib injury is not considered serious, but Falcons return remains uncertain
12 hrs agoEntertainment
K-pop Groups Face Backlash for Covering BTS’s “Dynamite”
A cover of BTS’s “Dynamite” at Music Bank in Barcelona drew criticism online, with fans saying the vocals fell short of the original.
“The number one reason K-Pop is dying is the decline in vocal ability.”
Hirosaki launches a new manga
Hirosaki is launching a new manga titled The Heroic Tale of the Villainous Prince. Further details are not provided.
SSS-Class Revival Hunter Premiere Called Worst Seen at NYCC 2026
A reviewer described the SSS-Class Revival Hunter premiere at New York Comic Con 2026 as the worst premiere they had seen there.
Voice Actor Manaka Iwami Announces Marriage and Birth of First Child
Voice actor Manaka Iwami announced that she is married and has had her first child.
Junji Itō’s “The Hanging Balloons” to Get a Thai Film Adaptation
Junji Itō’s short manga “The Hanging Balloons” is being adapted into a Thai film. No release or production details are provided.
South Korea lets registered music companies rate their own videos
A new law lets registered entertainment agencies and platforms assign age ratings to music videos and release them without waiting for government review. The system includes oversight to protect minors.
Red Riding Hood: A Detective Story Opens With a Question About Murder
The first episode of Red Riding Hood: A Detective Story asks what murder in a children's story would look like.
Red Riding Hood: A Detective Story begins by asking what murder in a children's story would look like.
The question combines the idea of a children's tale with a detective story.
The episode's focus is how murder might fit that kind of story.
The available details do not say who the characters are or what happens in the episode.
MAMA Song of the Year criteria draw criticism over Hwasa and BTS
After the 2026 MAMA nominations were announced, fans questioned the Song of the Year criteria, saying its global-reach weighting could disadvantage Hwasa and favor BTS.
Nominations for the 2026 MAMAs were announced, and the Song of the Year criteria were reported.
Fans posted criticism of the criteria and compared predictions for Hwasa’s “Good Goodbye” and BTS’s “SWIM.
Koreaboo published its article about the criticism.
The Coppersmith's Bride Manga to End in Three Chapters
The Coppersmith's Bride manga is set to conclude after three more chapters.
- Chapters remaining
- 3
- Report date
- October 13, 2026
- Outlet
- Anime News Network
FES☆TIVE apologizes after festival performance is stopped
FES☆TIVE said its set at a festival in Gunma was stopped at the organizers’ decision after dangerous audience behavior. The group apologized and said it plans another event soon.
Reason for interruption
The group said the organizers decided to stop the performance.
Critics said the interruption was warranted because of audience members’ dangerous behavior.
Apology and statement
The group apologized for the sudden interruption and announced plans for a festival without restrictions.
Critics questioned why the statement did not address the reported disruptive behavior and raised concerns about safety.
Lisa’s comments about singing in a documentary draw online mockery
A clip of BLACKPINK’s Lisa discussing her fears about singing has spread online, prompting mockery and debate about her abilities and training.
‘SSS-Class Suicide Hunter’ anime set for release next January
12 hrs ago
Matsuda Genta's Drama Kiss Scene Draws Fan Attention
5 hrs ago
Hirayasumi Anime Announces Five More Cast Members
5 hrs ago
New Chiikawa film illustration draws attention as screenings continue
5 hrs ago
TWICE fans criticize Sana’s photos in season’s greetings product
5 hrs ago
Kim Ji-won and Kim You-jung lead rival weekend dramas
5 hrs agoHealth
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
23 hrs ago
Aficamten Improves Exercise Capacity in Nonobstructive Heart Condition Trial
23 hrs agoGLP-1 drugs may have a role in addiction care, but questions remain
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Coal tar shampoo can ease persistent dandruff and scalp psoriasis
1 day ago
John Oliver examines quality and supply problems with generic drugs
1 day ago