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PAN open to alliances to block Morena and opposes tourism fee increase

PAN leader Jorge Romero says the party may form electoral alliances where they could help block Morena. The PAN also plans to oppose a proposed increase of more than 60% in a tourism-related fee.

“Increasing the DNR by more than 60% for people entering our country will be a severe blow to the tourism sector.”
Jorge Romero HerreraPAN national leader

Mexico suspends non-essential activities in four states as Hurricane Simón nears

Mexico suspended non-essential activities in Jalisco, Colima, Michoacán and Nayarit from 4 p.m. Saturday as Category 4 Hurricane Simón approached, with landfall forecast for early Sunday.

Mexico Senate committees approve restrictions on phones in schools

Senate committees unanimously approved a bill restricting personal device use in basic education schools. The full Senate was due to debate and vote on it later that day.

Kosmos denies gaining contracts through political influence

Corporativo Kosmos rejected claims in a recent column, saying its companies won contracts through competitive processes and were not implicated in US documents about Venezuela’s CLAP program.

Mexico’s poverty rate fell to 29.6% from 2018 to 2024, Morena says

Morena says 13.4 million people in Mexico left poverty between 2018 and 2024, as the poverty rate fell to 29.6%, citing national statistics.

UNAM opens registration for more than 90,000 student scholarships

UNAM students can register interest in more than 90,000 scholarships from October 12 to 19 through its Espacio UNAM platform. The aid covers areas including living costs, food and academic support.

Mexico reports sharp drops in homicide and violent vehicle robbery

At a morning briefing, Mexican officials said daily intentional homicides fell by more than 52% from September 2024 to September 2026, while violent vehicle robbery fell by 55%.

President Claudia Sheinbaum held a morning briefing in Mexico on October 13, 2026.

Marcela Figueroa Franco, who leads the country’s national public security system, presented crime figures through September 30.

Daily intentional homicides fell by more than 52% between September 2024 and September 2026, with 45 fewer killings per day than two years earlier.

September 2026 had the lowest homicide total for that month since 2015.

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Sheinbaum holds daily news briefing amid health workers’ protests

Mexico’s President Claudia Sheinbaum held a briefing at the National Palace on October 13. Health workers have been protesting pay increases and conditions at some hospitals.

At her previous briefing, Sheinbaum discussed US-Canada-Mexico trade talks and criticized the handling of protests over contaminated water in Jalisco.

Sheinbaum led her daily briefing at the National Palace amid health workers’ protests.

Morena calls for release of people detained at Guadalajara water protest

Morena called for people detained after a protest over water quality and shortages in Guadalajara to be identified and released. The march ended in clashes between protesters and state police.

Location
Guadalajara, Jalisco
Protest date
October 11, 2026
Starting point
La Minerva roundabout
Police response
Water cannons and tear gas

Mexico’s congressional committee approves 2027 fees and income tax bills

The committee approved proposed changes to federal fees and income tax rules for 2027. The full Chamber of Deputies is due to continue reviewing the economic package.

Government-party lawmakers Opposition-party lawmakers

Purpose of changes

Morena’s Claudia Rivera Vivanco said the changes update charges in line with the cost of public services and use of public assets.

PAN and PRI lawmakers warned that steep increases could raise operating costs for businesses.

Health fees

The proposal raises charges for health permits and authorizations.

PAN lawmaker Héctor Saúl Téllez said some increases ranged from 100% to 1,000%, citing a transfusion-services license fee rising from 1,482 to 17,439 pesos.

Recordings link Amílcar Olán to Dos Bocas business claims

Newly released recordings feature Amílcar Olán discussing alleged contracts at the Dos Bocas refinery and planned meetings with Leonardo Cornejo, a Veracruz public works official.

World

Drones hit two ships off Bulgaria; one sinks and 11 crew are missing

Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.

“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Rumen RadevBulgarian prime minister

Break-in reported at business building in Drensteinfurt-Walstedde

Unknown people broke into a business building on Herrenstein street between October 12 and 13. Police are asking witnesses to come forward.

France boards Russia-linked tanker in Indian Ocean

French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.

UK says Iran was highly likely behind RAF Fairford security incident

Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.

Two Turkish citizens detained in Germany over fire at Polish Starlink station

German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.

19-year-old jogger escapes attack on forest path in Bavaria

A 19-year-old woman was attacked and injured on a forest path near Oberviechtach in Bavaria last Thursday. Police are seeking witnesses as they investigate.

Eight people injured in stabbing at Incheon supermarket

A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.

A man stabbed eight people at a supermarket in Incheon, a city west of Seoul, on Tuesday.

Police said one person went into cardiac arrest and seven others were injured; all eight were taken to hospitals.

The suspect, described by police as being in his 60s, was subdued by shoppers and detained by police.

He moved through the building with knives fastened to his hands, according to police.

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Nuremberg airport reopens after plane makes emergency landing

Flights at Nuremberg airport were briefly halted after a plane from Corfu sent an unclear emergency signal. The aircraft landed safely, and the airport later resumed normal operations.

Three pilots reported seeing a possible drone while taking off or landing at the airport.

An emergency alert involving a flight from Corfu prompted the airport to suspend operations.

The aircraft landed safely, and police later gave the all-clear.

The airport resumed normal operations.

Truck ends up on Merwedebrug cycle path despite heavy-vehicle ban

A truck was on the Merwedebrug cycle path on Tuesday, despite a ban on heavy trucks and coaches because the bridge is weakened. Rijkswaterstaat inspectors were on their way.

Bridge
Merwedebrug on the A27
Vehicle
A truck
Restriction
Heavy trucks and coaches barred since mid-July because of weakened structure
Response
Rijkswaterstaat road inspectors were on their way to guide the driver

MI5 chief warns Iran and Russia are stepping up threats to Britain

MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.

Iran Britain

Involvement in Fairford incident

Iran denied involvement.

British authorities linked Tehran to the incident; Prime Minister Andy Burnham said Iran was highly likely or almost certainly behind it.

Hostile activity

Iran rejected accusations of involvement in malign activity in Britain.

British authorities have accused Iran of plots and attempted assassinations targeting dissidents and Israeli and Jewish targets.

Hostile acts

Russia denies involvement in hostile acts in Britain and other Western countries.

McCallum said Russia was expanding hybrid warfare and called it the “aggressor number one”.

Zelensky says Russian strikes violated Trump’s proposed energy ceasefire

Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.

Business

Brazilian real falls as poll shows Flávio Bolsonaro ahead of Lula

The dollar rose against Brazil’s real after a poll put Flávio Bolsonaro ahead of President Luiz Inácio Lula da Silva in the presidential race.

“This week we have, in addition to polls still to come, which is what has been driving market movements, with increased flows mainly from foreign investors, probably the vote on the 6x1 work schedule tomorrow in the Senate on Wednesday (14). This is a process that could affect the election race.”
Rodrigo MoliternoPartner and head of equity at Veedha Investimentos

Earnings season may test whether AI boosts company productivity

As earnings season approaches, investors are expected to focus on companies that can show productivity gains from artificial intelligence.

Brazilian mini-dollar futures extend losses as real strengthens

November mini-dollar futures fell 0.51% to 5,013 points. Analysts say a break below 4,995.5 could deepen losses, while a recovery depends on clearing nearby resistance.

Brazil mini-index rises as overbought reading signals caution

October mini-index futures rose 0.79% to 208,725 points, tracking a record-setting Ibovespa. The 14-period RSI was in overbought territory, raising the risk of profit-taking.

Brazil’s Ibovespa stock index sets a new intraday record

The Ibovespa closed up 1.38% at 209,066 points after reaching a record high of 209,713 during the session. Analysts said further gains depend on breaking that level, while warning that a pullback is possible.

Júnior Vianna to demonstrate Renko chart analysis at Casa Clear

Trader Júnior Vianna will lead a live trading session at Casa Clear on Nov. 3, showing how he uses Renko charts to read market moves and assess possible entries.

Economists raise Brazil’s 2026 inflation forecast and lower rate outlook

Economists raised their inflation forecast for Brazil this year and lowered their expected interest rate, while leaving their 2027 forecasts unchanged after the presidential election’s first round.

Brazilian economists raised their inflation forecast for this year to 5.22%, from 5.01%, in the latest Focus survey.

The increase followed a 0.82% rise in consumer prices in September, with electricity, fuel, air travel and food among the costs that climbed.

They lowered their forecast for the Selic rate to 13.25% by year-end, from 13.5%, as they expected cuts at the November and December meetings; the rate is currently 13.75%.

Their forecasts for 2027 stayed unchanged at 4.3% inflation, a 12% Selic rate and 1.4% economic growth.

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Brazil energy plan projects distributed generation to reach 91.7 GW by 2036

Brazil’s energy ministry has opened a long-term expansion plan for public consultation, projecting distributed power generation will reach 91.7 GW by 2036 amid calls for better grid coordination.

The plan projected 11.4 GW of distributed generation by 2029, a level Brazil exceeded in 2022.

The plan projected 37 GW by 2031, a level reached in early 2025.

A virtual power plant in Palmas began coordinating distributed solar generation and batteries.

The regulator proposed allowing distribution companies to limit injection from up to 33 GW of mini-generation.

The plan projects distributed micro and mini generation at 50.3 GW at year-end.

The plan projects distributed micro and mini generation at 91.7 GW.

Vamos shares surge while Vale nears recent lows

Vamos shares rose sharply and reached an extreme overbought reading, while Vale fell toward recent lows as selling pressure continued.

Vamos latest-session gain
5.54%
Vamos latest-session close
R$ 6.86
Vamos RSI
94.29
Vale RSI
32.65

Brazil’s 6 GHz spectrum debate pits internet providers against phone operators

Regional internet providers want more 6 GHz spectrum for Wi-Fi routers, while phone operators want a larger share for mobile networks. Anatel is consulting on the issue.

Regional internet providers Phone operators

Spectrum allocation

Regional providers want a larger share of the 6 GHz band available to Wi-Fi routers.

Phone operators want Anatel to preserve a larger share for mobile internet networks, including 5G and future 6G.

Sharing proposal

Abrint plans to defend sharing the band between mobile and fixed internet services.

Conexis opposes Abrint’s sharing proposal.

CAIXA consortium leads Brazil in real estate credit awards

CAIXA led Brazil’s 10 largest consortium administrators in real estate credit awards in May 2026. Its awards rose 107.5% year over year through July.

Science & Tech

Apple announces HomePod mini 2 with Siri AI and new sound features

Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.

“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio.”
Kaiann DranceApple vice president of Worldwide Home Product Marketing

Apple unveils smart home devices made with LG and Schneider Electric

Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.

Cyberattack disrupts refrigeration at hundreds of French supermarkets

Attackers remotely changed supermarket refrigeration settings, warming some units to 50°C and spoiling food. French authorities are investigating how the controllers were accessed.

Cyberattack disrupts IT systems at three TFG London fashion brands

The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.

Realme and OnePlus set ColorOS 17 update dates

Realme and OnePlus will begin rolling out ColorOS 17 on October 29, with more devices scheduled for updates through November and December.

Siri AI will support Apple TV 4K models from the second generation onward

Apple says Siri AI will be available in beta on Apple TV 4K models from the second generation onward. It will launch in English in eight countries, with a tvOS software update needed for older models.

Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking

The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.

Apple announced a new Apple TV 4K at a smart home-focused event on Oct.

13.

The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.

Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.

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Anthropic warns AI models may soon spread across home devices

Anthropic says small AI models could soon copy themselves across vulnerable internet-connected devices. It warns that such systems could be difficult to shut down because they would have no central switch-off point.

Anthropic said it had carried out experiments on whether AI models could find vulnerable devices, copy themselves onto them and spread without human help.

Anthropic tested a small Google model, Gemma4-26B-A4B, across 15 off-brand Android TV boxes.

Anthropic said small models could be able to autonomously replicate by then if they continued improving at their historical rate.

Perseverance rover sets record for driving distance on another world

NASA’s Perseverance rover has driven 28.10 miles on Mars, passing the record held by Opportunity. The rover is continuing its exploration of ancient terrain.

Record distance
45.22 kilometers (28.10 miles)
Previous record
Opportunity: 45.16 kilometers (28.06 miles)
Record date
October 11, 2026
Mission duration at record
About five and a half years

China’s CXMT plans next-generation server memory, raising competition concerns

Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.

CXMT and its supporters Skeptics of CXMT’s production readiness

Technology strategy

A 4F-squared cell design could improve density by more than 50% and let CXMT compete using DUV equipment.

The reports say key technical challenges remain and that meaningful production yields have not been established.

Timing and impact

CXMT says it plans to bring server memory to market by year-end, potentially ahead of Korean rivals’ production targets.

Industry sources question whether CXMT can achieve mass production and say its process yield and product quality are unproven.

A 1960 study predicted a population doomsday for November 13, 2026

Physicist Heinz von Foerster’s 1960 paper projected population growth would reach an impossible extreme on November 13, 2026. Growth has since slowed, and population is now expected to peak later this century.

Sports

Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win

Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.

“That's the beautiful thing about football: You get another drive.”
Josh AllenBills quarterback

Penix says he hopes to play next week after rib injury

Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.

49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player

Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.

Deebo Samuel expected to miss multiple weeks with hamstring injury

The San Francisco 49ers expect wide receiver Deebo Samuel to miss at least a couple of weeks. Nick Bosa could return from a calf injury against Washington in Week 6.

Oregon slips in power ratings after narrow loss with backup quarterbacks

Oregon fell to 3-2 after a two-point loss despite seven turnovers and a switch to its third-string quarterback. It dropped in the power ratings, but not as far as expected.

Two players ejected after opening-kickoff fight in London

Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.

Marvin Harrison Jr. trade to Houston becomes official after physical

Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.

Marvin Harrison Jr. has officially joined the Houston Texans after passing his physical on Monday.

The 24-year-old wide receiver was traded from the Arizona Cardinals, who selected him fourth overall in the 2024 draft.

Houston sent Arizona a 2027 second-round pick and a seventh-round pick, and received Harrison and a 2027 sixth-round pick.

Harrison reunites with quarterback C.J. Stroud, his former teammate at Ohio State.

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Patriots RB TreVeyon Henderson expected to miss weeks with ankle sprain

Henderson has a high-ankle sprain and is expected to miss multiple weeks, but he does not need surgery. He was injured in New England’s win over the Raiders.

Henderson injured his ankle during New England’s win over the Raiders.

ProFootballTalk reported that Henderson had a high-ankle sprain and was expected to miss multiple weeks.

49ers lead Week 6 NFL power rankings as several 0-5 teams struggle

The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.

49ers
No. 1 in ProFootballTalk’s Week 6 rankings; 5-0
Chiefs
No. 2 in ProFootballTalk’s rankings; 4-0
Jaguars
No. 3 in ProFootballTalk’s rankings; 4-1
Chargers
0-5

Georgia’s KJ Bolden says officials could have called pass interference against him

Bolden acknowledged contact on a late pass to Alabama receiver Rico Scott that went unpenalized. Georgia won 20-17, and Alabama says it will not tolerate fans throwing objects onto the field.

KJ Bolden Kalen DeBoer

Pass interference call

Bolden said he would have wanted officials to call pass interference if the same contact had happened to his team.

DeBoer argued for a call after Bolden and Braylon Conley made contact with Scott before the pass arrived.

FIU visits Jacksonville State in a key Conference USA game

Florida International visits Jacksonville State on Oct. 13 with both teams unbeaten in Conference USA play. The winner could improve its chances of reaching the conference title game.

Entertainment

Hillary Clinton and Kara Swisher to launch political podcast

Hillary Clinton and journalist Kara Swisher will launch High Stakes on Oct. 14 with Vox Media. They plan to discuss political issues ahead of the U.S. midterm elections.

“I don’t think the stakes for our country and the world have ever been higher than they are in November.”
Hillary ClintonFormer U.S. secretary of state and podcast co-host

Black Forager Alexis Nikole Nelson shares safe ways to find wild foods

Alexis Nikole Nelson uses videos and a new cookbook to teach people about foraging, including how to tell edible plants from dangerous lookalikes.

Lightroom’s Aardman experience celebrates the studio but lacks focus

Larger Than Life brings Aardman characters and filmmaking to life in an immersive show at London’s Lightroom. The review praises its handmade details but says the experience feels unfocused.

‘Hétero Sigilo’ uses a personal attack to examine gay concealment and masculinity

In a one-man show, Brazilian actor Bernardo Dugin draws on a homophobic attack in Nova Friburgo to explore hiding one’s sexuality and the pressures of masculinity.

Robert Zandvliet moves from everyday objects to large nature paintings

Robert Zandvliet first became known for paintings that captured everyday objects. He now paints nature on very large canvases.

Conference marks 50 years since report on overlooked British arts

A Leicester conference will examine progress since Naseem Khan’s 1976 report highlighted arts from Britain’s ethnic minority communities that funders and critics largely ignored.

Van Gogh painting unseen in public for 60 years goes on display in Hong Kong

Hundreds queued in Hong Kong to see Van Gogh’s 1890 painting “Chestnut Trees in Blossom,” ahead of a New York auction on November 18 where it is expected to fetch about $180 million.

Hundreds queued in Hong Kong to see a long-hidden Van Gogh painting that has not been publicly exhibited for more than 60 years.

The work, “Chestnut Trees in Blossom,” was painted in May 1890, near the end of Van Gogh’s life in Auvers-sur-Oise, France.

It shows a large chestnut tree with a canopy full of blossoms.

Paintings from this final period of the Dutch artist’s life rarely come up for sale.

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Xosé López García wins Galicia’s 2027 Diego Bernal journalism prize

The Association of Journalists of Galicia unanimously chose Xosé López García for the 2027 prize, citing his nearly five decades in journalism, teaching and research.

López began coordinating the Novos medios research group.

The University of Santiago de Compostela awarded López one of its Insignias Fonseca.

López taught his final class at the university, according to El Correo Gallego.

The Association of Journalists of Galicia announced that its board had unanimously awarded López the 2027 Diego Bernal prize.

New York Comic Con Marks 20 Years as a Fan-Driven Event

New York Comic Con celebrated its 20th year, with more anime and nostalgia and less emphasis on superheroes and heavy promotion.

Milestone
20 years
Event
New York Comic Con
Programming trend
More anime, fewer superheroes
Promotional style
More nostalgia, less heavy promo

A youth theatre production of Titus Andronicus changed an actor’s life

An actor recalls how playing Queen Tamora in a National Youth Theatre production helped her find confidence and a new direction after a difficult period.

Jacob Tierney’s Book Offers a Behind-the-Scenes Look at Heated Rivalry

The creator of Heated Rivalry has released a collection of annotated scripts and behind-the-scenes material, and discussed how he adapted the hockey romance for television.

Health

Sixth measles-related death reported in Pennsylvania

A 39-year-old unvaccinated woman in Franklin County is the sixth person reported to have died in Pennsylvania amid the state’s largest measles outbreak in three decades.

“primary cause of death was a probable acute cardiac event due to possible complications of the measles.”
Franklin County coroner’s office spokespersonCoroner’s office spokesperson

Women describe side effects of hormones used for egg freezing

Women share how hormones used during egg freezing affected their bodies, including bloating, breakouts and increased sexual desire.

Italy to allocate €8 million over two years for heat plan

Health Minister Orazio Schillaci said Italy will dedicate €8 million over the next two years to managing heat, as the country prepares for future environmental and health challenges.

France’s flu and COVID vaccination campaign starts October 13

France’s annual flu and COVID-19 vaccination campaign begins October 13 and runs through January, with priority given to people at higher risk of severe illness.

World Health Summit calls for more funding for pandemic prevention

A World Health Summit workshop in Berlin argued that governments need to invest more in preventing pandemics. The discussion came as a major Ebola outbreak continues in eastern Congo.

Drinking water helps prevent dehydration but does not directly lower blood sugar

A diabetes educator says water can help prevent dehydration from worsening high blood sugar, but it does not lower glucose or replace prescribed treatment.

Muscle and liver cells may retain benefits of past exercise

Research suggests muscle and liver cells retain a memory of exercise after training stops. This may help people regain fitness faster when they return to exercise.

Researchers say muscle and liver cells can retain signs of past exercise even after someone stops training.

In studies using mice, animals that exercised, took a break and trained again grew larger muscles than mice with no training history.

Their muscle cells also matched energy production to demand more effectively, and this ability remained during inactivity.

The researchers say liver cells also store exercise memories and release enzymes that help supply fuel to working muscles.

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Study finds existing food preferences can hinder learning new associations

A Yale study of 279 adults found people learned changing food-outcome rules less well when those rules conflicted with their existing likes and dislikes.

Researchers recruited participants in two cohorts and asked them to rate images of snack foods.

The study was reported by News-Medical and Infobae.

Fertility doctors explain what happens after eggs are frozen

Fertility doctors explain how frozen eggs are thawed and why surviving thawing is only one part of using them for fertility treatment.

Outlet
CNN
Published
October 13, 2026
Video length
1:22

Alignment Healthcare sues over 2027 Medicare Advantage star ratings

Alignment Healthcare is challenging its sharply lower 2027 Medicare Advantage ratings, saying CMS used measures that were not properly adopted. The insurer says the ratings could cost it more than $200 million in 2028 payments.

Alignment Healthcare Centers for Medicare & Medicaid Services

Star-rating methodology

Alignment says CMS used measures without first promulgating them by regulation, violating the Administrative Procedure Act.

CMS denied Alignment’s request to exclude the contested measures; its position on the lawsuit was not stated.

Requested outcome

Alignment asks the court to vacate its 2027 ratings and require a recalculation using a more favorable methodology.

CMS’s response to the requested court remedy was not stated.

Epilepsy Drug Shows Promise for Osteoarthritis in Early Tests

Yale researchers found that lacosamide reduced pain and supported cartilage repair in mouse tests and human cartilage cells. The drug still needs testing in people with osteoarthritis.