Trending
Apple unveils $299 HomeView smart home hub
Apple unveiled HomeView, a smart home hub with a display for device controls, calls and media. Pre-orders begin today, and it goes on sale November 13.
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Agreement
The U.S. reached a diesel agreement with Russia.
European officials recoiled from the agreement, and Ukraine called it “a gift” to Putin.
Response to Moscow
Not stated.
Allies vowed to keep pressure on Moscow.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
Power bank fire diverts IndiGo flight from Delhi to Hyderabad
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Maresca says City need a perfect game to beat PSG
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Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
42 mins ago
Judge halts tree removal at Washington golf course project
18 hrs ago
First look shows Michael B. Jordan and Austin Butler in Miami Vice reboot
22 hrs ago
Brazilian axé singer Netinho dies at 60
25 mins agoPolitics
L. Murugan resigns as minister and plans to focus on BJP in Tamil Nadu
L. Murugan has resigned as a Union minister and said he will give his full time to strengthening the BJP in Tamil Nadu ahead of the 2029 general election.
“With humility and grateful heart, I therefore request you to relieve me of my responsibility as MoS and permit me to relinquish my membership of the Rajya Sabha, so that I may dedicate full time to strengthening the party in Tamil Nadu”
Former Turkish deputy minister jailed pending trial in fund investigation
Mustafa Aksu, a former deputy agriculture minister, was jailed pending trial in an investment fund investigation. Turkey’s regulator ordered 131 funds liquidated after a market crisis.
Federal agents search Ilhan Omar’s Washington home
Agents searched the home of Democratic Rep. Ilhan Omar as part of an ongoing criminal investigation. Omar called the search political intimidation; no charges against her were announced.
King Felipe VI and Queen Letizia begin first official visit to Ceuta
Felipe VI and Letizia began their first official visit to Ceuta, months after a mass arrival of migrants from Morocco. They are staying overnight in the city.
Spain's government criticizes political dispute over overseas voters' suspension
Spain's Supreme Court kept a suspension affecting more than 163,000 overseas voters in place. The government is considering whether to challenge the decision in the Constitutional Court.
Spanish expatriate councils defend voting rights for descendants of exiles
Nearly 30 councils representing Spaniards abroad say a court order could prevent some newly naturalized descendants of exiles from voting in Spain’s 29 November elections.
Greta Thunberg joins French students protesting school conditions
Greta Thunberg joined students in Saint-Denis as protests over teacher shortages, crowded classes and poor school buildings spread across France. Officials said about 200 schools were closed.
Greta Thunberg joined French students protesting in Saint-Denis, a suburb north of Paris, on Tuesday.
The students are demanding action on teacher shortages, overcrowded classes and deteriorating school buildings.
The movement began in late September and has led to marches and blockades at schools across the country.
Unions and some left-wing groups support the protests, while officials said about 200 schools were closed on Tuesday.
Italian Chamber approves majority budget resolutions
Italy’s Chamber of Deputies approved majority resolutions on a budget deviation and the public finance plan, including calls to support household purchasing power and investment.
The government approved the public finance planning document.
The Chamber approved the majority resolution on the budget deviation and a separate resolution on the public finance planning document.
The Senate approved majority resolutions on the document and the budget deviation.
Hungary removes anti-LGBT+ provisions from 2021 law
Hungary’s parliament voted to remove provisions restricting references to homosexuality and gender identity for minors from a 2021 child-protection law. It is the first significant reversal of such restrictions since Peter Magyar took power in May.
- Vote
- 139 in favor, 51 against
- Law amended
- 2021 Child Protection Law
- Former leader
- Viktor Orbán
- Prime minister
- Péter Magyar
TSE review found no alleged fake news in Janones's WhatsApp channel
A technical team at Brazil’s top electoral court found no copies of the alleged fake news in André Janones’s WhatsApp channel. A temporary order to suspend it was later reversed.
Alleged content
The campaign alleged that the channel circulated claims about Flávio Bolsonaro that the TSE had previously ruled to be disinformation.
The TSE technical review found no matching or substantially equivalent claims in the posts it examined.
Channel suspension
The campaign sought action over the alleged content.
Janones’s channel was restored after the suspension was reversed, with Cueva citing freedom of expression.
Spain moves to add 500 judges and 200 prosecutors in 2027
The government is starting an urgent process to create 500 judge posts and 200 prosecutor posts for 2027, adding to a similar expansion approved in July.
Ministry says nearly 150 education staff hurt in student protests
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Philippine Senate accepts withdrawal of three charges against Sara Duterte
3 hrs ago
BJP women MPs ask President to intervene over Congress MP’s suspension
1 hr ago
Indonesia Says It No Longer Needs Forests for Rice, but Project Future Is Unclear
1 hr ago
Poilievre to press for tariff-free trade during Detroit visit
4 mins ago
Italy gives go-ahead to autonomy agreements with three regions
6 mins agoWorld
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Nuremberg airport suspends flights after aviation emergency alert
Nuremberg airport in Germany suspended flights after an unclear aviation emergency was reported. Police said an aircraft landed safely, and the cause is under investigation.
Two Turkish citizens detained in Germany over fire at Polish Starlink station
German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.
Court orders new hearing in case over passport error that stopped family’s Thailand trip
A passport error listing a child’s sex incorrectly stopped a Krasnodar family from travelling to Thailand. A court overturned earlier rulings and sent the compensation case back for a new hearing.
Hezbollah to offer up to $14,000 to Lebanese families with destroyed homes
Hezbollah says it will pay eligible Lebanese families whose primary homes were destroyed or made uninhabitable in the war with Israel, with payments spread over a year.
Polish foreign minister says a European army could form by 2030
Radosław Sikorski said a joint European force could be formed by 2030, possibly limited to the Baltic states and the eastern flank.
MI5 chief warns Iran and Russia are stepping up threats to Britain
MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.
MI5 chief Ken McCallum warned of growing state threats to Britain in a speech in London on Tuesday.
He said Iran had shifted towards targeting harder sites, including military locations, although he could not discuss an investigation into a suspected plot involving RAF Fairford.
British Prime Minister Andy Burnham said Tehran was highly likely to be behind that suspected plot, but Iran has denied involvement.
McCallum said Iran-linked operations had led to more than 50 arrests over the past year.
Eight people injured in stabbing at Incheon supermarket
A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.
A man attacked people with knives while moving on an escalator in the supermarket building.
Shoppers subdued the suspect, and police arrested him.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
- Vessel
- DF Peak
- Location
- More than 450 nautical miles south of Réunion
- Flag
- Benin
- EU sanctions status
- Listed among the EU-sanctioned ships
UK says Iran was highly likely behind RAF Fairford security incident
Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.
Responsibility
Burnham said the incident was highly likely to have been coordinated in Iran and almost certainly directed by the IRGC.
Iran rejected any suggestion it was involved and called the accusation unfounded and malicious speculation.
Evidence
British authorities cited their assessment and said investigators found accelerants but no viable explosives in vans.
Iran called on Britain to present evidence supporting its allegations.
Zelensky says Russian strikes violated Trump’s proposed energy ceasefire
Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.
Japan and US to review off-duty rules after Okinawa killing
3 hrs ago
Russian drone strike on Rivne university injures 20
55 mins ago
Spanish royals visit Ceuta after deadly migration crisis
2 hrs ago
Zelenskyy says Ukraine received no warning before Russian missile strike on Kyiv
1 hr ago
Israel turns back Ethiopian Airlines cargo flight over Indonesian pilot
1 hr ago
Bus and tram collide in Marseille, leaving four people injured
3 hrs agoBusiness
Japanese firms offer personalized bath products and training
Japanese companies are promoting tailored bath products made with regional ingredients, while a new online certification course teaches people about bathing culture.
“share the joy of bathing”
Workplace expert offers advice on building better ties with junior colleagues
A workplace development expert explains why people may feel uneasy around junior colleagues and offers advice informed by the real-life experiences of Kishitaka no.
IMF raises Japan’s 2026 growth forecast to 0.7%
The IMF raised its forecast for Japan’s economic growth in 2026 to 0.7% and expects growth to stabilize next year.
Aeon's net profit nearly tripled as drugstore business performed well
Japanese retailer Aeon said its net profit for the six-month interim period was 13.3 billion yen, about three times the level a year earlier. Strong drugstore business helped drive the increase.
Aeon’s net profit triples to 13.3 billion yen in March-August period
Aeon reported net profit of 13.3 billion yen for March to August 2026, 3.3 times the year-earlier figure, as shopping malls and drugstores performed well.
Aeon’s first-half profit rises 1.7%, but second-quarter profit falls 23.5%
Aeon reported first-half recurring profit of ¥108.2 billion, up 1.7% from a year earlier. Profit in the three months to August fell 23.5%.
Japan’s 2026 rice harvest forecast to fall 1%
Japan’s 2026 rice harvest is projected to fall 1%. The forecast is relatively high despite concerns about prolonged rain in September.
Japan's 2026 rice harvest is projected to fall 1%.
The forecast is still described as relatively high.
The outlook comes amid concerns about prolonged rain in September.
Those concerns relate to the rain's possible impact on the harvest.
Nissin to relaunch Black Pepper Crab Cup Noodles in Japan
Nissin Foods will launch its revamped Black Pepper Crab Cup Noodles nationwide in Japan on October 26, inspired by a Singapore crab dish.
Nissin launched Black Pepper Crab Cup Noodles.
Nissin announced the product’s return.
The product is scheduled to go on sale nationwide in Japan.
Japan-controlled tankers return to the Middle East after months away
Japan-controlled tankers have returned to the Middle East after months away, during more than seven months of conflict in the Persian Gulf.
- Tankers
- Japan-controlled
- Return
- Middle East
- Conflict duration
- More than seven months
Hyogo company offers plant-based alternative to Akashi octopus
A company in Hyogo Prefecture has begun offering a plant-based substitute for Akashi-brand octopus after its price rose sharply.
Japan has 1.55 million borrowers with three or more unsecured loans
At the end of fiscal 2025, 1.55 million people in Japan had three or more unsecured, unguaranteed loans from moneylenders, the highest number in 12 years.
Singapore venture firm plans startup academy in Japan's Iwate Prefecture
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Boeing plans first 737 MAX delivery to ANA from December
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Uniqlo to release four monochrome Miffy UT designs in December
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Nomura funds lead Japan’s 10-year investment trust returns
11 hrs ago
Ferrari Amalfi Spider debuts as an entry model priced above 40 million yen
11 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
Apple reportedly plans HomeView smart home hub for November
Apple is expected to unveil its Siri-focused HomeView display on October 13 and begin shipping it around mid-November. A new Apple TV and HomePod mini are also expected.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Scientists call for stronger safeguards against AI hacking
An international group of scientists, including dozens of Canadians, is urging stronger safeguards for AI models after several reported hacking incidents.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
SpaceXSI bundles X Premium, Grok and Cursor in one subscription
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Ahold Delhaize takes some systems offline after cyberattack
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Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
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Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
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CISA adds five exploited software flaws amid China-linked espionage concerns
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A 1960 study predicted a population doomsday for November 13, 2026
1 hr agoSports
Bills beat Rams 37-34 in overtime for Josh Allen’s first OT win
Buffalo beat Los Angeles 37-34 in overtime after Josh Allen led a late drive and Tyler Bass kicked the winning field goal. It was Allen’s first career overtime victory.
“Guys kept chipping away, defense kept going out there making plays, special teams was big tonight”
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
- Suspension
- One game without pay
- Teams
- San Francisco 49ers and Seattle Seahawks
- Players involved
- Dre Greenlaw and Ernest Jones IV
- Game result
- San Francisco won 32-29
Rams' limited investment in special teams faces renewed scrutiny
After another overtime loss, coach Sean McVay again criticized the Rams' special teams. The team has ranked near the bottom in several measures of investment in that unit.
Two players ejected after opening-kickoff fight in London
Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.
Commanders and Giants tie 27-27 after Washington runs out of time in overtime
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UCLA quarterback Nico Iamaleava expected to miss season with knee injury
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Bills stay in Los Angeles before short-week game in Las Vegas
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Penix’s rib injury is not considered serious, but Falcons return remains uncertain
12 hrs ago
Huntley leads Ravens comeback for 30-23 overtime win over Falcons
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Kenneth Walker III and Mike Evans lead early NFL free-agent rankings
3 hrs agoEntertainment
Selma Blair charged with assault after flight incident in New York
Selma Blair faces two second-degree assault charges over alleged attacks on a police officer and a nurse after a Delta flight landed at JFK. She was released on bail and has a court hearing scheduled for January.
“This was not an intentional assault.”
God of War Laufey Collector Box Costs $149.99 and Excludes the Game
Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.
IDFA to open with film following Myanmar resistance recruits
The 39th International Documentary Film Festival Amsterdam will open with “White Tiger Column,” following young recruits as they train with Myanmar’s resistance movement. The festival runs Nov. 12 to 22.
The Social Reckoning opens to $5.5 million, far below its predecessor
Aaron Sorkin’s follow-up to The Social Network took in $5.5 million in its domestic opening weekend, against a reported production budget of about $30 million to $42 million.
Bryan Cranston mourns Breaking Bad co-star RJ Mitte, who died at 34
Cranston paid tribute to Mitte, who played his son on Breaking Bad, remembering his acting and disability advocacy. Accounts differ on whether his death was officially confirmed as suicide.
RimWorld moves to its own engine, with faster performance and saves intact
Update 1.7 moves RimWorld from Unity to Ludeon Studios’ Waylith Engine. The studio says it runs two to four times faster, and existing saves and most mods still work.
Thélyson Orélien denies using AI to write novel, admits plagiarism
The Canadian-Haitian author says no sentence in his novel was created by AI, but apologized for plagiarizing other writers’ work.
Thélyson Orélien denies that AI wrote any sentence of his novel, “C’était ça ou mourir.”
The Canadian-Haitian writer says he used tools for research but wrote the book himself.
He apologized and accepted responsibility for plagiarizing texts by established authors after moving to Canada.
He says he began writing the novel in Quebec in 2017 and finished a first draft in 2019.
TNA ends Max Caster’s run after Riyadh attack reference at Bound for Glory
TNA said Max Caster will no longer wrestle for the company after his entrance rap at Bound for Glory referred to attacks in Riyadh. TNA apologized and removed the segment from replays and social media.
Wrestling Observer dated the attack at King Khalid International Airport in Riyadh to this day.
Caster performed an entrance rap referencing the Riyadh attacks before his match against Moose at Bound for Glory.
TNA announced Caster would no longer wrestle for the promotion and said it had removed the segment from replays and social media.
Raye manually reviews ticket sign-ups after 1.8 million apply for 5,000 seats
Raye says AI bots and scalpers overwhelmed sign-ups for her Royal Albert Hall show in London. Her team is manually selecting fans for presale access, with remaining tickets due to go on general sale.
- Sign-ups
- 1.8 million
- Venue capacity
- 5,000 seats
- Venue
- Royal Albert Hall, London
- Show date
- 23 October 2026
Collin Gosselin alleges abuse by mother Kate ahead of memoir release
Collin Gosselin says his mother, Kate, physically and emotionally mistreated him as a child. His memoir, “In the Shadow of Eight,” is due out Oct. 13.
Alleged treatment
Collin says his mother dragged him by the ear and mistreated him and his siblings.
Kate previously said reports of abuse were unfounded.
His placement in an institution
Collin says he was removed from the home and placed in an institution, with little contact with his family.
Kate said he was sent for treatment for educational and social challenges and that the decision was the best thing she could do for him.
Julianne Moore’s son Caleb Freundlich marries Kibriyaá Morgan
Caleb Freundlich and Kibriyaá Morgan have married after dating for nine years. His mother, actor Julianne Moore, shared the news on Instagram.
Amanda Seyfried says she is uncomfortable filming sex scenes for now
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Taylor Swift’s ‘Patient Zero’ holds the No. 1 spot on the Hot 100
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God of War Laufey Collector’s Box Will Not Include the Game
1 hr ago
RTL removes Unter Uns morning reruns ahead of planned end
3 hrs ago
Apple announces Vision Pro horror film Remnants for October 16
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Hugh Grant backed out of replacing Charlie Sheen on Two and a Half Men
46 mins agoHealth
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
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