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SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
Purpose of the deal
Kagame said the partnership could bring jobs, skills, tourism and business opportunities. Formula 1 described it as a long-term commitment with a vision for meaningful impact.
Critics have labeled Rwanda’s sports sponsorship policy sportswashing.
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
Power bank fire diverts IndiGo flight from Delhi to Hyderabad
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Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
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Judge halts tree removal at Washington golf course project
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37 mins agoPolitics
Nearly 5,000 Dutch students have debts of at least €100,000
Nearly 5,000 students and former students in the Netherlands had study debts of €100,000 or more in 2026, up from more than 3,000 a year earlier. High debts can reduce how much borrowers can get for a mortgage.
“Repaying a hundred thousand in study debt is manageable for the average student.”
Dutch domestic violence hotline warns it cannot keep up with reports
Veilig Thuis says rising reports and staff shortages are causing long waits to assess possible domestic violence and child abuse, and is asking the government for more funding.
Rising interest rates add pressure to heavily indebted governments
Higher US borrowing is pushing up interest rates worldwide, increasing the burden on governments with large debts. France is especially exposed because it has high debt and weak growth.
First stone laid for Agnetentuin redesign in Sittard
A first stone has been laid for the redesign of Agnetentuin in Sittard. No details about the changes or timetable are given.
Two-way shipping resumes on the IJssel between Arnhem and Zutphen
Ships can again travel in both directions on the IJssel after rising water levels ended a one-way restriction. The change means inland vessels no longer need to make long detours.
Wadden Sea centre faces bankruptcy after public funding offer withdrawn
The municipality of Het Hogeland and Groningen province say they will not help keep the Wadden Sea centre in Lauwersoog financially afloat. Its directors will seek a rescue plan over the next two weeks or apply for bankruptcy.
Dutch cabinet maintains ban on takeover of DigiD manager Solvinity
The Dutch cabinet is holding to its ban on a takeover of Solvinity, which manages DigiD.
The Dutch cabinet is keeping its ban on a takeover of Solvinity.
Solvinity is identified as the manager of DigiD.
The decision means the takeover remains prohibited.
The information available does not name the proposed buyer or explain the cabinet’s reason.
The Netherlands will not add more dental school places despite a growing shortage
Education Minister Rianne Letschert rejected advice to expand dentist training, citing its cost. The government will instead add places for dental hygienists from 2027-28.
The Capacity Body recommended raising dental school places to 386 per year.
Education Minister Rianne Letschert announced she would not add more dental school places, citing the cost of expansion.
The number of dental school places will rise from 270 to 290.
An additional 28 students will be allowed to start dental hygienist training, bringing the total to 381.
Dutch government legal costs rose 14% to €51.1 million in 2025
The Dutch government spent 14% more on law firm Pels Rijcken in 2025, bringing the total to €51.1 million. Justice and Defence were among the ministries paying more.
- Year
- 2025
- Legal firm
- Pels Rijcken
- Government spending
- €51.1 million
- Increase
- Nearly 14%
Dutch official must review whether three pig farms broke tail-docking rules
A Dutch court ruled that the state secretary for agriculture must assess whether three pig farmers met the conditions for docking piglets’ tails and whether enforcement is needed.
Reason for tail docking
Farmers say shortening pigs’ tails is needed to prevent them from biting each other.
The group says better living conditions can prevent tail biting.
Enforcement request
Erkens rejected the group’s requests, citing uncertainty about the standards for enforcement.
The group sought action against three farmers for docking tails despite the general legal ban.
Column says Pim Fortuyn’s rise cost politics a valuable tool
A weekly political column says Pim Fortuyn’s rise coincided with the loss of a valuable political tool and argues that behind-the-scenes politics could use support.
Dutch provinces have planted only 4,000 hectares under national forest plan
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Page explains how to search and follow news topics
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Dutch water board chief expects emergency drought measures in coming summers
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Dutch tax plan faces broad opposition in parliament
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The Netherlands prepares for emergencies amid fears of power loss
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Opposition parties oppose tax increase in government plan
20 hrs agoWorld
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Nuremberg airport suspends flights after aviation emergency alert
Nuremberg airport in Germany suspended flights after an unclear aviation emergency was reported. Police said an aircraft landed safely, and the cause is under investigation.
Two Turkish citizens detained in Germany over fire at Polish Starlink station
German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.
Court orders new hearing in case over passport error that stopped family’s Thailand trip
A passport error listing a child’s sex incorrectly stopped a Krasnodar family from travelling to Thailand. A court overturned earlier rulings and sent the compensation case back for a new hearing.
Hezbollah to offer up to $14,000 to Lebanese families with destroyed homes
Hezbollah says it will pay eligible Lebanese families whose primary homes were destroyed or made uninhabitable in the war with Israel, with payments spread over a year.
Polish foreign minister says a European army could form by 2030
Radosław Sikorski said a joint European force could be formed by 2030, possibly limited to the Baltic states and the eastern flank.
MI5 chief warns Iran and Russia are stepping up threats to Britain
MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.
MI5 chief Ken McCallum warned of growing state threats to Britain in a speech in London on Tuesday.
He said Iran had shifted towards targeting harder sites, including military locations, although he could not discuss an investigation into a suspected plot involving RAF Fairford.
British Prime Minister Andy Burnham said Tehran was highly likely to be behind that suspected plot, but Iran has denied involvement.
McCallum said Iran-linked operations had led to more than 50 arrests over the past year.
Eight people injured in stabbing at Incheon supermarket
A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.
A man attacked people with knives while moving on an escalator in the supermarket building.
Shoppers subdued the suspect, and police arrested him.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
- Vessel
- DF Peak
- Location
- More than 450 nautical miles south of Réunion
- Flag
- Benin
- EU sanctions status
- Listed among the EU-sanctioned ships
UK says Iran was highly likely behind RAF Fairford security incident
Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.
Responsibility
Burnham said the incident was highly likely to have been coordinated in Iran and almost certainly directed by the IRGC.
Iran rejected any suggestion it was involved and called the accusation unfounded and malicious speculation.
Evidence
British authorities cited their assessment and said investigators found accelerants but no viable explosives in vans.
Iran called on Britain to present evidence supporting its allegations.
Zelensky says Russian strikes violated Trump’s proposed energy ceasefire
Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.
Israel turns back Ethiopian Airlines cargo flight over Indonesian pilot
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Japan and US to review off-duty rules after Okinawa killing
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One killed in GC-2 crash as second collision snarls traffic near Las Palmas
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Russian drone strike on Rivne university injures 20
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Spanish royals visit Ceuta after deadly migration crisis
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Zelenskyy says Ukraine received no warning before Russian missile strike on Kyiv
1 hr agoBusiness
ILO and Switzerland provide Rp584.3 billion in support to Indonesian small businesses
A program backed by the ILO and Switzerland has helped 25,378 Indonesian small businesses access Rp584.3 billion in financing and formal savings. A third phase is being prepared.
“The most important thing is not just how many people gain access, but the behavioral changes and economic resilience that they experience.”
Hashim says Indonesia could raise an additional Rp 1,500 trillion a year
Hashim Djojohadikusumo says Indonesia collects less than it could because revenue is about 12% of GDP. The government aims to lift the ratio to 18% within two to three years.
Pertamina brings 30 local businesses to Indonesia Grand Prix in Lombok
Thirty small businesses took part in a bazaar at the 9–11 October Grand Prix in Lombok. Their food, crafts and personal-care products were presented to local and international visitors.
Businesses push back against sweeping halal rules in major Muslim nation
Businesses are facing sweeping halal rules in the world’s biggest Muslim nation, prompting a backlash.
Rupiah weakens as US dollar rises to around 17,900
The rupiah fell at the start of trading on Tuesday as the US dollar strengthened. Reports put the dollar at 17,920 to 17,948 rupiah.
Indonesia’s main stock index falls 2.59% to a three-month low
The Jakarta Composite Index fell 2.59% on Monday, reaching its lowest level in three months as investors sold shares and weighed global risks.
Pertamina adjusts fuel supplies amid queues in Bondowoso
Pertamina says Pertalite use in Bondowoso rose 16–20%, while road congestion linked to dock repairs slowed deliveries. The company is redirecting supplies and tightening checks.
Vehicles queued at several fuel stations in Bondowoso, a district in East Java, as demand for Pertalite rose.
Pertamina Patra Niaga says consumption of the subsidized fuel was about 16–20% above normal.
The company links the increase to more public activity and some customers switching from non-subsidized fuel.
At the same time, traffic congestion on the Ketapang–Banyuwangi route, where a dock is being repaired, has made delivery timing harder.
PGUN Says It Was Not Involved in Share Pledges by Three Major Shareholders
PGUN says three major shareholders pledged all their shares as security for credit arranged by its affiliate, Jhonlin Baratama, with Bank Mandiri. PGUN says it gave no guarantees and will receive none of the funds.
The three shareholders were reported to have pledged all their PGUN shares to Bank Mandiri; the articles give different dates.
The pledge was disclosed through information filed with the Indonesia Stock Exchange.
Tamlikho’s statement was cited in a PGUN disclosure, according to CNN Indonesia.
Detik reported PGUN’s explanation, citing an Indonesia Stock Exchange disclosure.
Jakarta Plans Rp4.24 Trillion in Regional Bonds for 2027
Jakarta plans to issue Rp4.24 trillion in regional bonds in 2027 and Rp1.38 trillion in 2028 to help fund infrastructure and public services.
- 2027 planned issuance
- Rp4,239,353,292,725
- 2028 planned issuance
- Rp1,382,070,000,000
- Two-year planned total
- Rp5,621,423,292,725
- Announcement date
- October 13, 2026
Fuel queues persist in Bali as Pertamina boosts supplies
Long queues continued at some Bali gas stations despite resumed deliveries. Pertamina says rising Pertalite use drove the shortage and has brought in more fuel, with further shipments scheduled.
PLN Batam Denies Claim of Three-Day Power Outage
PLN Batam says a viral graphic claiming power would be cut for three days is false. The company also denies plans to limit electricity to six hours a day.
Dharma Polimetal Commissioner Sells 143,300 Shares
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Jhonlin Baratama Completes Purchase of 30.25% Stake in Bayan Resources
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Rupiah weakens to 17,948 per US dollar in Tuesday morning trading
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GoTo shareholders to consider capital reduction and deputy CEO’s resignation
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Antam 1-gram gold price falls Rp20,000 to Rp2.574 million
12 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
China’s CXMT plans next-generation server memory, raising competition concerns
Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Scientists call for stronger safeguards against AI hacking
An international group of scientists, including dozens of Canadians, is urging stronger safeguards for AI models after several reported hacking incidents.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
SpaceXSI bundles X Premium, Grok and Cursor in one subscription
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Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
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Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
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CISA adds five exploited software flaws amid China-linked espionage concerns
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Meta launches Muse Wonder AI models aimed at catching up with rivals
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Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win
Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.
“That's the beautiful thing about football: You get another drive.”
FIU visits Jacksonville State in a key Conference USA game
Florida International visits Jacksonville State on Oct. 13 with both teams unbeaten in Conference USA play. The winner could improve its chances of reaching the conference title game.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
Model backs Penn State and Auburn against the spread in Week 7
A computer model recommends Penn State to cover against Michigan and Auburn to cover against Georgia in Week 7. It simulates each FBS game 10,000 times.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
- Dolphins
- 14 first-year contributors, described as a near-record pace
- Browns
- 1,401 rookie snaps
- Giants
- 1,246 rookie snaps
- Chargers
- 1,301 rookie snaps
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Two players ejected after opening-kickoff fight in London
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Commanders and Giants tie 27-27 after Washington runs out of time in overtime
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Penix’s rib injury is not considered serious, but Falcons return remains uncertain
12 hrs agoEntertainment
Selma Blair charged with assault after flight incident in New York
Selma Blair faces two second-degree assault charges over alleged attacks on a police officer and a nurse after a Delta flight landed at JFK. She was released on bail and has a court hearing scheduled for January.
“This was not an intentional assault.”
God of War Laufey Collector Box Costs $149.99 and Excludes the Game
Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.
Bryan Cranston mourns Breaking Bad co-star RJ Mitte, who died at 34
Cranston paid tribute to Mitte, who played his son on Breaking Bad, remembering his acting and disability advocacy. Accounts differ on whether his death was officially confirmed as suicide.
IDFA to open with film following Myanmar resistance recruits
The 39th International Documentary Film Festival Amsterdam will open with “White Tiger Column,” following young recruits as they train with Myanmar’s resistance movement. The festival runs Nov. 12 to 22.
The Social Reckoning opens to $5.5 million, far below its predecessor
Aaron Sorkin’s follow-up to The Social Network took in $5.5 million in its domestic opening weekend, against a reported production budget of about $30 million to $42 million.
RimWorld moves to its own engine, with faster performance and saves intact
Update 1.7 moves RimWorld from Unity to Ludeon Studios’ Waylith Engine. The studio says it runs two to four times faster, and existing saves and most mods still work.
Thélyson Orélien denies using AI to write novel, admits plagiarism
The Canadian-Haitian author says no sentence in his novel was created by AI, but apologized for plagiarizing other writers’ work.
Thélyson Orélien denies that AI wrote any sentence of his novel, “C’était ça ou mourir.”
The Canadian-Haitian writer says he used tools for research but wrote the book himself.
He apologized and accepted responsibility for plagiarizing texts by established authors after moving to Canada.
He says he began writing the novel in Quebec in 2017 and finished a first draft in 2019.
TNA ends Max Caster’s run after Riyadh attack reference at Bound for Glory
TNA said Max Caster will no longer wrestle for the company after his entrance rap at Bound for Glory referred to attacks in Riyadh. TNA apologized and removed the segment from replays and social media.
Wrestling Observer dated the attack at King Khalid International Airport in Riyadh to this day.
Caster performed an entrance rap referencing the Riyadh attacks before his match against Moose at Bound for Glory.
TNA announced Caster would no longer wrestle for the promotion and said it had removed the segment from replays and social media.
Raye manually reviews ticket sign-ups after 1.8 million apply for 5,000 seats
Raye says AI bots and scalpers overwhelmed sign-ups for her Royal Albert Hall show in London. Her team is manually selecting fans for presale access, with remaining tickets due to go on general sale.
- Sign-ups
- 1.8 million
- Venue capacity
- 5,000 seats
- Venue
- Royal Albert Hall, London
- Show date
- 23 October 2026
Collin Gosselin alleges abuse by mother Kate ahead of memoir release
Collin Gosselin says his mother, Kate, physically and emotionally mistreated him as a child. His memoir, “In the Shadow of Eight,” is due out Oct. 13.
Alleged treatment
Collin says his mother dragged him by the ear and mistreated him and his siblings.
Kate previously said reports of abuse were unfounded.
His placement in an institution
Collin says he was removed from the home and placed in an institution, with little contact with his family.
Kate said he was sent for treatment for educational and social challenges and that the decision was the best thing she could do for him.
Julianne Moore’s son Caleb Freundlich marries Kibriyaá Morgan
Caleb Freundlich and Kibriyaá Morgan have married after dating for nine years. His mother, actor Julianne Moore, shared the news on Instagram.
Amanda Seyfried says she is uncomfortable filming sex scenes for now
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Taylor Swift’s ‘Patient Zero’ holds the No. 1 spot on the Hot 100
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God of War Laufey Collector’s Box Will Not Include the Game
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RTL removes Unter Uns morning reruns ahead of planned end
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Apple announces Vision Pro horror film Remnants for October 16
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Hugh Grant backed out of replacing Charlie Sheen on Two and a Half Men
58 mins agoHealth
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
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