Trending
Apple unveils $299 HomeView smart home hub
Apple unveiled HomeView, a smart home hub with a display for device controls, calls and media. Pre-orders begin today, and it goes on sale November 13.
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Agreement
The U.S. reached a diesel agreement with Russia.
European officials recoiled from the agreement, and Ukraine called it “a gift” to Putin.
Response to Moscow
Not stated.
Allies vowed to keep pressure on Moscow.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
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Judge halts tree removal at Washington golf course project
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26 mins agoPolitics
Trump’s Russian diesel deal draws bipartisan criticism in Congress
Trump says he struck a deal with Putin to import Russian diesel to lower U.S. fuel prices. Lawmakers say it could support Russia’s war in Ukraine and violate U.S. law.
“The harm to the Ukrainians is real”
Los Angeles moves to make some nitrous oxide sales a crime
The Los Angeles City Council unanimously approved a ban on cannabis and tobacco retailers selling or distributing nitrous oxide. The mayor plans to sign it, and violations could bring jail time.
Katie Zacharia begins term as White House press secretary
Katie Zacharia is starting her term as White House press secretary. President Trump said she will hold an introductory news conference Tuesday at 9:30 a.m.
Trump’s plan to import Russian diesel draws bipartisan criticism
Trump says Russia will supply diesel to help ease high fuel prices, but seven senators say the plan conflicts with a 2022 ban on Russian energy imports.
Judge orders halt to taxpayer-funded ads promoting Trump
A federal judge temporarily barred the Trump administration from airing taxpayer-funded ads promoting the president and ordered it to cancel the remaining advertising purchase.
Trump says he may meet North Korea's Kim in November
Trump said he may meet Kim Jong Un during a November trip to Asia, which includes stops in Manila and Shenzhen. No meeting has been confirmed.
Federal agents search Ilhan Omar’s Washington home
Agents searched the home of Democratic Rep. Ilhan Omar as part of an ongoing criminal investigation. Omar called the search political intimidation; no charges against her were announced.
Federal agents searched the Washington home of Ilhan Omar, a Democratic member of Congress from Minnesota.
The Justice Department said the search was carried out under a court-authorised warrant as part of an ongoing criminal investigation, but did not name Omar or explain the investigation.
News reports linked the search to a fraud inquiry about immigration paperwork filed by Omar’s late father when she was a child; officials have not confirmed that link.
Omar, who came to the United States from Somalia as a child, said the search was an attempt to target political opponents.
Elon Musk gives more than $276 million to Republican groups since July
Musk has donated more than $276 million to Republican groups since July, making him the biggest known donor of the 2026 midterm elections. The largest share went to a group backing Republican Senate candidates.
Musk said he planned to do less political spending in the future.
Musk gave more than $276 million to Republican groups.
News outlets reported the newly disclosed donations, ahead of a federal filing deadline.
Political committees are due to report their third-quarter finances.
Republicans face elections as they seek to hold their congressional majorities.
Former DOGE staff raise at least $500 million for private firms
At least two dozen former DOGE staff have moved into private businesses, and firms they co-founded or invested in have raised at least $500 million.
- Funding raised
- At least $500 million
- Former staffers identified
- At least two dozen
- DOGE operating period
- January 20 to July 4, 2025
- DOGE claimed savings
- $215 billion
US archbishop urges Catholic soldiers to avoid planned Hasan execution
Archbishop Timothy Broglio told Catholic service members to seek exemption from the planned firing squad execution of Nidal Hasan, which the Pentagon wants to livestream in December.
Purpose of public broadcast
Broglio questioned the value of broadcasting the execution and said it could harm the military’s reputation.
Hegseth said making the event public would help people understand the serious consequences of such acts.
Participation by Catholic service members
Broglio urged Catholics assigned to the firing squad to request exemption because participation would violate Church teaching.
Hegseth described using military members to carry out the execution; the sources do not state his view on religious exemptions.
Tillis says Trump’s Russian diesel deal may break the law
Senator Thom Tillis says Trump’s decision to ease sanctions on Russian diesel may violate US law. Tillis says the move could affect his support for year-end funding.
Poll finds most Americans see Trump as profiting unethically or illegally
3 hrs ago
Federal agents search Ilhan Omar’s Washington home in immigration paperwork probe
18 hrs ago
Johnson says he would stay on as House GOP leader if party loses majority
21 hrs ago
Poll puts Democrats 7 points ahead on generic congressional ballot
4 hrs ago
Fort Hood families oppose plan to livestream Hasan’s execution
11 hrs ago
Appeals court confirms Justice owes nearly $30 million to bond provider
4 hrs agoWorld
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Nuremberg airport suspends flights after aviation emergency alert
Nuremberg airport in Germany suspended flights after an unclear aviation emergency was reported. Police said an aircraft landed safely, and the cause is under investigation.
Two Turkish citizens detained in Germany over fire at Polish Starlink station
German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.
Court orders new hearing in case over passport error that stopped family’s Thailand trip
A passport error listing a child’s sex incorrectly stopped a Krasnodar family from travelling to Thailand. A court overturned earlier rulings and sent the compensation case back for a new hearing.
Hezbollah to offer up to $14,000 to Lebanese families with destroyed homes
Hezbollah says it will pay eligible Lebanese families whose primary homes were destroyed or made uninhabitable in the war with Israel, with payments spread over a year.
Polish foreign minister says a European army could form by 2030
Radosław Sikorski said a joint European force could be formed by 2030, possibly limited to the Baltic states and the eastern flank.
MI5 chief warns Iran and Russia are stepping up threats to Britain
MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.
MI5 chief Ken McCallum warned of growing state threats to Britain in a speech in London on Tuesday.
He said Iran had shifted towards targeting harder sites, including military locations, although he could not discuss an investigation into a suspected plot involving RAF Fairford.
British Prime Minister Andy Burnham said Tehran was highly likely to be behind that suspected plot, but Iran has denied involvement.
McCallum said Iran-linked operations had led to more than 50 arrests over the past year.
Eight people injured in stabbing at Incheon supermarket
A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.
A man attacked people with knives while moving on an escalator in the supermarket building.
Shoppers subdued the suspect, and police arrested him.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
- Vessel
- DF Peak
- Location
- More than 450 nautical miles south of Réunion
- Flag
- Benin
- EU sanctions status
- Listed among the EU-sanctioned ships
UK says Iran was highly likely behind RAF Fairford security incident
Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.
Responsibility
Burnham said the incident was highly likely to have been coordinated in Iran and almost certainly directed by the IRGC.
Iran rejected any suggestion it was involved and called the accusation unfounded and malicious speculation.
Evidence
British authorities cited their assessment and said investigators found accelerants but no viable explosives in vans.
Iran called on Britain to present evidence supporting its allegations.
Zelensky says Russian strikes violated Trump’s proposed energy ceasefire
Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.
Japan and US to review off-duty rules after Okinawa killing
3 hrs ago
Russian drone strike on Rivne university injures 20
56 mins ago
Spanish royals visit Ceuta after deadly migration crisis
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Zelenskyy says Ukraine received no warning before Russian missile strike on Kyiv
1 hr ago
Israel turns back Ethiopian Airlines cargo flight over Indonesian pilot
1 hr ago
Bus and tram collide in Marseille, leaving four people injured
3 hrs agoBusiness
McDonald’s Switzerland brings back The Prime for its 50th anniversary
The burger, created by TV chef René Schudel, won a fan vote and is returning to McDonald’s restaurants across Switzerland for a limited time, while stocks last.
Henry Schirmer to become Cofra CFO in January 2027
Cofra has named Henry Schirmer as its next CFO, starting 1 January 2027, subject to regulatory approval. He will succeed Florian Brenninkmeyer.
More vacant homes point to slight easing in Zurich rental market
Zurich’s vacancy rate rose from 0.48% to 0.52% in 2026, as lower net migration and more construction eased pressure. The market remains tight.
“In the canton of Zurich, after rising pressure, the first signs of easing are emerging. There is no all-clear, but the market is moving away from maximum scarcity.”
UBS customers receive overnight activation-code texts after technical problem
A UBS customer received two texts asking her to use an activation code after midnight. The bank reportedly told her the messages were linked to a technical problem.
UBS veteran Claudio Scarfone to retire at the end of October
Claudio Scarfone, a UBS executive who worked with independent wealth managers for more than 25 years, will retire at the end of October 2026.
Flexbase’s Aargau data centre and battery face financing and permit questions
Flexbase is building a data centre in Laufenburg, Switzerland, alongside a huge battery. The project faces questions over its financing, technology and missing permits for the battery and grid connection.
S&P cuts Zurich’s outlook to negative, keeps top credit ratings
S&P lowered Zurich’s outlook from stable to negative but kept its AAA long-term and A-1+ short-term ratings. It cited rising debt, spending and investment plans.
S&P Global Ratings has changed its outlook for the city of Zurich from stable to negative.
It has not lowered the city’s credit ratings, which remain AAA for long-term debt and A-1+ for short-term debt.
The agency says rising spending and a large investment programme could make it harder for Zurich to control deficits and debt.
It projects that debt could reach about 90% of the city’s current revenue by 2028, up from 63% in 2023.
Givaudan's third-quarter organic growth accelerates to 8.6%
The Swiss fragrance and flavour maker reported faster growth in the third quarter, with its flavour business recovering and fragrance sales continuing to lead.
Givaudan recorded organic growth of 3.6%; Taste & Wellbeing grew by 0.5%.
Organic growth reached 8.6%, with Taste & Wellbeing up 3.5% and Fragrance & Beauty up 13.5%.
Sales totalled 5.89 billion Swiss francs, with organic growth of 5.2%.
Bank Syz appoints new private banking head and chief operating officer
Marc Brodard will lead private banking at Bank Syz, while Martin Freiermuth becomes COO, overseeing operations, technology and security.
- Private banking head
- Marc Brodard
- Chief operating officer
- Martin Freiermuth
- Brodard’s reporting line
- Philippe Turrian, head of wealth management
- Freiermuth’s reporting line
- CEO Nicolas Syz
NZZ editor succession reportedly pits Mark Dittli against Benedict Neff
A Swiss media outlet says Mark Dittli is a contender to lead the NZZ, while alleging that outgoing editor Eric Gujer favors Benedict Neff. The claims have not been confirmed here.
Suitability
Inside Paradeplatz presents Dittli as a candidate with business experience from founding The Market.
The article says Gujer wants Neff, an NZZ editor, installed as his successor.
Political profile
The article says Zimmermann portrayed Dittli as left-wing because he briefly led Republik in 2018.
The article describes Neff as aligned with Gujer, but gives no account of Neff’s own political views.
Schweiter names Stefan Boenders as its new CFO
Stefan Boenders will become CFO of Schweiter Technologies on November 1, 2026, succeeding Urs Scheidegger, who is leaving at the end of December.
Schlatter technology chief Daniel Fransson dies in holiday accident
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Givaudan quarterly organic sales beat market expectations on fragrance strength
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Phoeniqs expands Swiss-based AI infrastructure for banks and businesses
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Zurich Zoo drops its iconic red “h” after 30 years
10 hrs ago
Swiss 10-year fixed mortgage rates reach highest level since March 2025
11 hrs ago
Negotiation coach advises workers to name their target salary, not their minimum
18 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
Apple reportedly plans HomeView smart home hub for November
Apple is expected to unveil its Siri-focused HomeView display on October 13 and begin shipping it around mid-November. A new Apple TV and HomePod mini are also expected.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Scientists call for stronger safeguards against AI hacking
An international group of scientists, including dozens of Canadians, is urging stronger safeguards for AI models after several reported hacking incidents.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
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Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
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Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
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A 1960 study predicted a population doomsday for November 13, 2026
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Bills beat Rams 37-34 in overtime for Josh Allen’s first OT win
Buffalo beat Los Angeles 37-34 in overtime after Josh Allen led a late drive and Tyler Bass kicked the winning field goal. It was Allen’s first career overtime victory.
“Guys kept chipping away, defense kept going out there making plays, special teams was big tonight”
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
- Suspension
- One game without pay
- Teams
- San Francisco 49ers and Seattle Seahawks
- Players involved
- Dre Greenlaw and Ernest Jones IV
- Game result
- San Francisco won 32-29
Rams' limited investment in special teams faces renewed scrutiny
After another overtime loss, coach Sean McVay again criticized the Rams' special teams. The team has ranked near the bottom in several measures of investment in that unit.
Two players ejected after opening-kickoff fight in London
Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.
Commanders and Giants tie 27-27 after Washington runs out of time in overtime
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UCLA quarterback Nico Iamaleava expected to miss season with knee injury
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Bills stay in Los Angeles before short-week game in Las Vegas
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Penix’s rib injury is not considered serious, but Falcons return remains uncertain
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Huntley leads Ravens comeback for 30-23 overtime win over Falcons
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Kenneth Walker III and Mike Evans lead early NFL free-agent rankings
3 hrs agoEntertainment
Collin Gosselin alleges abuse by mother Kate ahead of memoir release
Collin Gosselin says his mother, Kate, physically and emotionally mistreated him as a child. His memoir, “In the Shadow of Eight,” is due out Oct. 13.
“Simply put, my whole life that I lived was a lie,”
Silvia Salis says assisted fertility led to her son’s birth
The mayor of Genoa says she and her husband, Fausto Brizzi, turned to assisted fertility after a year of trying for a child. Their son Eugenio was born in 2023 and has his mother’s surname.
Sean Lennon says he and Julian received equal inheritances
Sean Lennon said he and his half brother Julian inherited the same amount from their father, John Lennon, with Julian’s trust slightly larger by a negligible amount.
Prithvi Shaw and Akriti Agarwal reconcile after calling off engagement
Actor Akriti Agarwal said she and Indian cricketer Prithvi Shaw have chosen to be together again, weeks after ending their engagement. She said outside opinions influenced her decision.
Sean Combs returned to Fort Dix after reported head injury
Sean “Diddy” Combs was taken by ambulance from a New Jersey prison for treatment of a reported head injury and later returned. His listed release date is now March 2, 2028.
Jai Arrow and Berina Colakovic hold second wedding in Sicily
South Sydney Rabbitohs player Jai Arrow and Berina Colakovic held an intimate wedding ceremony in Sicily after marrying in Sydney in July. The couple celebrated with 65 guests.
Julianne Moore’s son Caleb Freundlich marries Kibriyaá Morgan
Caleb Freundlich and Kibriyaá Morgan have married after dating for nine years. His mother, actor Julianne Moore, shared the news on Instagram.
Caleb Freundlich and Kibriyaá Morgan are married after nine years together.
Freundlich is the son of actor Julianne Moore and director Bart Freundlich, and Morgan is his longtime partner.
Moore shared the news on Instagram on October 12, posting a video of the newlyweds dancing after their ceremony.
The couple met while studying at Davidson College and announced their engagement in August 2024.
Harry Styles urges people to look after each other after ICE shooting
At a Madison Square Garden show, Styles named Oscar Belgal, who was shot by an ICE agent in the Bronx while his five-year-old son was in the car. Belgal survived and is being held in detention.
NME reported that Belgal was shot in his car while his five-year-old son was in the back seat.
Mayor Zohran Mamdani held a press conference and condemned the shooting and the agents’ tactics, according to Billboard.
Styles spoke about Belgal at night 21 of his Madison Square Garden residency, according to Billboard.
Billboard published its report on Styles’ speech.
NME published its report on Styles’ tribute.
Kelly Clarkson disputes Brooklyn store’s account of shopping encounter
Kelly Clarkson says a Brooklyn store employee offered her a cheaper alternative to a singing bird listed with a price tag. The store says the bird is a wall fixture and was not for sale.
- Store
- Art of Play
- Location
- Brooklyn, New York
- Item
- Molly, a singing and dancing bird automaton
- Price Clarkson said she was quoted
- $15,000
Russell Brand’s London trial begins with jury selection
Brand denies seven charges of rape and sexual offences involving six women. Jury selection began at Southwark Crown Court, with prosecutors expected to open their case on Wednesday.
Charges
Brand has pleaded not guilty and denies wrongdoing.
Prosecutors allege he committed rape, sexual assault and indecent assault against six women.
Tobey Maguire officiates ex-wife Jennifer Meyer’s Hawaii wedding
Jewellery designer Jennifer Meyer married music executive Geoff Ogunlesi in Hawaii on October 10. Her former husband, Tobey Maguire, officiated the ceremony weeks after their divorce was finalised.
Ferran Adrià says he earned the equivalent of €2,000 a month at elBulli
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Keegan Allen Robbed at Gunpoint Outside West Hollywood Grocery Store
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Devon Sawa says he has learned to embrace his role in Casper
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Matthew Lowe and Emily Markus marry in Santa Barbara
1 day ago
Cindy Crawford and Rande Gerber seen together after son’s death
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Meghan shares video of Archie and Lilibet walking in the English countryside
21 hrs agoHealth
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
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