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Apple unveils $299 HomeView smart home hub
Apple unveiled HomeView, a smart home hub with a display for device controls, calls and media. Pre-orders begin today, and it goes on sale November 13.
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Agreement
The U.S. reached a diesel agreement with Russia.
European officials recoiled from the agreement, and Ukraine called it “a gift” to Putin.
Response to Moscow
Not stated.
Allies vowed to keep pressure on Moscow.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
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26 mins agoPolitics
Alberta referendum advance polls set to open this week
Elections Alberta says it is ready to deliver the referendum as advance polls are set to open this week.
Former rivals Notley and Kenney to appear together before separation vote
Former political rivals Notley and Kenney are set to attend an event ahead of a vote on separation.
Carney urges Alberta to stay in Canada ahead of separation vote
Albertans vote on October 19 on whether to begin the process of holding a binding referendum on leaving Canada. Prime Minister Mark Carney is urging them to remain in the country.
“A week from today, Albertans will have the opportunity to make an important decision about their future, whether to remain part of Canada or begin a long and uncertain process through which Alberta could separate from Canada.”
Canada’s military faces aging equipment and years of neglect
Canada’s military faces aging equipment and concerns about readiness as the country plans billions of dollars in new defence spending.
Retired general says Canada lacks staff for two fighter fleets
Canada is considering adding Swedish Gripen fighters to its planned F-35 purchase. A retired air force lieutenant general says running both programs would stretch personnel.
Benchmark Canada compares more than 40 measures of the country’s performance
The Macdonald-Laurier Institute has launched Benchmark Canada, a project that compares more than 40 measures of Canada’s performance with those of countries facing similar issues.
Kenney and Notley to oppose Alberta leaving Canada at event
Former Alberta premiers Jason Kenney and Rachel Notley will speak at an Edmonton event opposing separation, days before voters decide on 10 referendum questions.
Former Alberta premiers Jason Kenney and Rachel Notley will unite against separation at an event in Edmonton.
The Edmonton Chamber of Commerce is hosting them on Tuesday.
The former political rivals led opposing parties: Kenney’s United Conservative Party defeated Notley’s NDP government in 2019.
Albertans will vote on 10 referendum questions on Monday.
Alberta advance voting opens for 10-question referendum
Advance voting runs Tuesday to Saturday ahead of Alberta’s Oct. 19 referendum on 10 questions about immigration, constitutional issues and the province’s future in Canada.
The Government of Canada listed the Pacific Link pipeline as a project of national interest.
Elections Alberta advised voters to mail special ballots by this date to ensure they arrived by the return deadline.
Advance voting for the Alberta referendum takes place.
The deadline for Elections Alberta to receive mail-in ballots is 5 p.m.
Alberta referendum voting day takes place.
Carney urges Alberta to stay in Canada ahead of referendum vote
Mark Carney urged Albertans to stay in Canada in a video filmed at his former high school, a week before voters decide whether to pursue a binding referendum on leaving.
- Video location
- St. Francis Xavier High School, Edmonton
- Ballot questions
- 10
- Polls on staying in Canada
- 70 per cent or more of Albertans reportedly wanted to stay
- Vote timing
- The following Monday, according to the article
Poll finds broad Canadian support for closer ties with the EU
Nearly eight in 10 Canadians surveyed supported or somewhat supported associate EU membership if it boosted trade and defence co-operation. The EU has no such legal membership category now.
Purpose
Supporters favour associate membership to increase co-operation on trade and defence.
Heubner said the poll may reflect frustration with the United States, not a genuine desire for formal EU ties.
Sovereignty
Associate membership would stop short of full EU membership.
Heubner said EU membership involves giving up political power and decision-making in key areas; Nanos said Canadians do not want to give up sovereignty to diversify the economy.
Brandon seeks a way to deal with long-vacant downtown buildings
Brandon’s abandoned McKenzie Seeds building has resisted repeated redevelopment efforts. The city says vacant properties create safety risks, but its options are limited when owners keep paying property taxes.
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Canadian tech leaders ask Carney for tax incentives in next budget
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Quebec premier-elect vows to pursue independence referendum by 2030
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Canada’s military faces new operational spending review despite rising defence funds
10 hrs agoWorld
EU adds €25 million for migration cooperation in eastern Libya
The EU has signed an additional €25 million for border management, search-and-rescue and anti-smuggling work in eastern Libya, as it seeks to curb irregular migration to Europe.
“Libya remains the top country of departure for illegal crossings to the EU”
At least 72 gold miners killed in strike near Sudan-Egypt border
A Sudanese rights group says air strikes killed at least 72 gold miners near the Egypt-Sudan border. It blamed Egypt, which has not commented, but the claim has not been independently verified.
At least 139 migrants dead after boat capsizes off Djibouti
A boat carrying 305 people from Djibouti to Yemen capsized near Obock. At least 139 people died, 84 are missing and 82 survived.
Oil and gas eruption in eastern Niger causes severe environmental incident
An oil and gas eruption at a Nigerien oil site has been under way since September 25. Two workers were injured, and authorities say it is only partly contained.
AKA and Tibz murder trial adjourned as defence challenges firearm evidence
The trial over the 2023 murders of rapper AKA and businessman Tibz in Durban was adjourned as the defence challenged evidence linking a firearm to one accused.
G-24 urges cheaper financing as developing economies face high debt costs
G-24 chair Taiwo Oyedele said developing economies face high borrowing costs and debt risks, and urged the IMF and World Bank to offer vulnerable countries more affordable financing.
Attacks push Kaduna residents from homes and drive up city rents
Kidnappings and attacks are driving residents from communities outside Kaduna, Nigeria, into the city, where demand for apartments has pushed rents higher.
Repeated kidnappings and attacks are driving residents from communities outside Kaduna into areas they consider safer within the city.
Some homeowners have left properties they spent years building, while others are trying to sell at prices they consider too low.
Rents have risen as more people seek homes in the city; some three-bedroom apartments along Gwamna Road now cost 3 million to 3.5 million naira, up from 1.2 million to 1.5 million.
These newer communities had offered lower-income residents a way to buy land and build homes gradually.
Egypt’s Baha’i community faces a shortage of burial space
Cairo’s last remaining cemetery for Egypt’s Baha’i community is nearly full, while requests for burial grounds in other cities have been rejected, according to community members.
Baha’i merchants brought the faith to Egypt.
A court ruling allowed people outside Islam, Christianity and Judaism to leave a dash in the religion field on identity documents.
Hanan Kamal El-Din won an individual court ruling recognising her Baha’i marriage.
A higher court overturned that ruling.
The Straits Times reported that Egypt’s Baha’i community’s last remaining burial place was quickly running out of room.
African Union holds Kigali talks to advance eastern DRC peace process
Three former African presidents met Rwandan officials and regional representatives in Kigali to discuss security, refugee protection and cooperation as fighting continues in eastern DRC.
- Kigali consultations
- October 6; year not stated
- Goma meetings
- October 5; eastern DRC
- AU delegation
- Sahle-Work Zewde, Uhuru Kenyatta and Mokgweetsi Masisi
- Washington Peace Agreement
- Signed by the DRC and Rwanda on June 27, 2025
Climate activists protest African Energy Week in Cape Town
Greenpeace Africa and Extinction Rebellion campaigners protested in Cape Town against new oil and gas exploration in Africa. Police removed the protesters.
New oil and gas exploration
Activists called for an end to new oil and gas exploration across the continent.
The government is seeking to expand oil and gas development to attract investment and bolster energy security.
Role of natural gas
Activists said expanding fossil fuel use would conflict with climate commitments to reduce emissions.
The government presents natural gas as a complement to renewable energy, saying gas-fired plants could provide electricity when wind and solar output drops.
Sánchez confirms Moroccan warships entered Ceuta waters in July
Pedro Sánchez confirmed that Moroccan warships entered waters near Ceuta on 30 and 31 July, as large numbers of migrants arrived from Morocco. Spain sent naval ships to the area.
Islamic Development Bank Group and Nigeria strengthen development partnership
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Saudi Crown Prince Congratulates Abiy Ahmed on Re-election as Ethiopia’s Prime Minister
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Flights to Mekelle resume after Ethiopian forces retake city
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Local NGO to co-manage wildlife reserve in the DRC for the first time
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Africa's energy wealth contrasts with 560 million people without electricity
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Rights group warns Senegal crackdown is deterring HIV care
22 hrs agoBusiness
JP Morgan raises Apple price target to $360 despite iPhone demand concerns
JP Morgan raised its Apple price target from $340 to $360, saying reported iPhone 18 Pro production cuts may reflect normal adjustments. It expects the iPhone Duo to help offset a delayed base-model launch.
“there is nothing beyond the typical production adjustments Apple makes every year.”
Apple reportedly cuts iPhone 18 Pro parts orders amid weaker demand
Apple has reportedly asked suppliers to reduce parts production for the iPhone 18 Pro and Pro Max. One account puts October order cuts at 15% to 20%.
Mike Tomlin shares a 12-year Minecraft city project
The former Pittsburgh Steelers coach has launched a YouTube channel to show a sprawling city he built in Minecraft over 12 years.
Sushi-Con 2026 draws crowds to New York expo
More than 60 companies took part in Sushi-Con 2026 in New York, where visitors sampled Japanese foods and watched a bluefin tuna-cutting show.
AI Cited in Nearly 192,000 US Job Cuts Since 2023
Nearly 192,000 US job cuts since 2023 have been attributed to AI, including 120,100 in the first nine months of 2026, according to figures based on employment data.
IMF sees US inflation rising in 2026 before easing in 2027
The IMF forecasts US inflation at 3.6% in 2026 and 2.8% in 2027, with underlying inflation not returning to its 2% target until mid-2028.
UnitedHealth raises its profit forecast again as turnaround efforts advance
UnitedHealth raised its profit forecast again as its turnaround efforts gathered pace. No forecast figure or further details were provided.
UnitedHealth has raised its profit forecast again.
The company’s turnaround efforts are gathering pace, according to the headline.
A profit forecast is an estimate of how much profit a company expects to make.
The headline gives no new forecast figure or details about the changes behind the increase.
Bumble reportedly in advanced talks for a $1bn takeover
Bumble shares rose almost 50% after a report that technology holding company Ithaca is in advanced talks to buy the dating app firm for around $1bn.
Whitney Wolfe Herd launched Bumble.
Bumble listed on Nasdaq and later reached a market value of more than $14bn.
A report said Bumble was in advanced takeover talks, and its shares rose almost 50%.
Ithaca could announce a deal to buy Bumble, according to the Wall Street Journal report cited by the BBC.
Warner Music sues Ray-Ban owner over alleged use of its music in ads
Warner Music Group sued Luxottica and affiliated companies, alleging they used at least 427 Warner works in social media marketing without licenses or payment.
- Works cited
- At least 427 Warner-controlled works
- Defendants
- Luxottica Group S.p.A. and five affiliated companies
- Court
- US District Court for the Southern District of New York
- Followers
- 36.14 million combined social media followers, according to Warner’s law firm
Starbucks denies plans to buy Chipotle
Starbucks said it is not planning to buy Chipotle, contradicting a Financial Times report that it had been working on a possible offer. Starbucks shares rose after the denial, while Chipotle shares fell.
Takeover plans
Starbucks said it was not buying Chipotle.
The Financial Times reported that Starbucks had worked on a takeover offer.
Bison plans first drilling at Nevada’s Bald Peaks gold-silver target
Bison Resources has filed a notice for seven drill pads at Bald Peaks in Nevada. It is targeting a December 2026 start, after rock-chip assay results are due by the end of October.
Treasuries rise as Asian equity losses spur haven demand
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Wall Street closes mixed as technology shares fall
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IVV ETF offers low-cost exposure to about 500 US companies
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Alphabet plans to increase AI investment significantly next year
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Fuel costs and tariffs add to US inflation pressures
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eBay expands live shopping to more sellers ahead of holiday season
13 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
Apple reportedly plans HomeView smart home hub for November
Apple is expected to unveil its Siri-focused HomeView display on October 13 and begin shipping it around mid-November. A new Apple TV and HomePod mini are also expected.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Scientists call for stronger safeguards against AI hacking
An international group of scientists, including dozens of Canadians, is urging stronger safeguards for AI models after several reported hacking incidents.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
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Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
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Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
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CISA adds five exploited software flaws amid China-linked espionage concerns
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A 1960 study predicted a population doomsday for November 13, 2026
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Bills beat Rams 37-34 in overtime for Josh Allen’s first OT win
Buffalo beat Los Angeles 37-34 in overtime after Josh Allen led a late drive and Tyler Bass kicked the winning field goal. It was Allen’s first career overtime victory.
“Guys kept chipping away, defense kept going out there making plays, special teams was big tonight”
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
- Suspension
- One game without pay
- Teams
- San Francisco 49ers and Seattle Seahawks
- Players involved
- Dre Greenlaw and Ernest Jones IV
- Game result
- San Francisco won 32-29
Rams' limited investment in special teams faces renewed scrutiny
After another overtime loss, coach Sean McVay again criticized the Rams' special teams. The team has ranked near the bottom in several measures of investment in that unit.
Two players ejected after opening-kickoff fight in London
Jacksonville’s Bryan Thomas Jr. and Philadelphia’s Jeremiah Trotter Jr. were ejected after fighting during the opening kickoff. A 90-yard Jaguars return for a touchdown was called back because of penalties.
Commanders and Giants tie 27-27 after Washington runs out of time in overtime
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Bills stay in Los Angeles before short-week game in Las Vegas
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Penix’s rib injury is not considered serious, but Falcons return remains uncertain
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Huntley leads Ravens comeback for 30-23 overtime win over Falcons
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Kenneth Walker III and Mike Evans lead early NFL free-agent rankings
3 hrs agoEntertainment
Selma Blair charged with assault after flight incident in New York
Selma Blair faces two second-degree assault charges over alleged attacks on a police officer and a nurse after a Delta flight landed at JFK. She was released on bail and has a court hearing scheduled for January.
“This was not an intentional assault.”
God of War Laufey Collector Box Costs $149.99 and Excludes the Game
Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.
IDFA to open with film following Myanmar resistance recruits
The 39th International Documentary Film Festival Amsterdam will open with “White Tiger Column,” following young recruits as they train with Myanmar’s resistance movement. The festival runs Nov. 12 to 22.
The Social Reckoning opens to $5.5 million, far below its predecessor
Aaron Sorkin’s follow-up to The Social Network took in $5.5 million in its domestic opening weekend, against a reported production budget of about $30 million to $42 million.
Bryan Cranston mourns Breaking Bad co-star RJ Mitte, who died at 34
Cranston paid tribute to Mitte, who played his son on Breaking Bad, remembering his acting and disability advocacy. Accounts differ on whether his death was officially confirmed as suicide.
RimWorld moves to its own engine, with faster performance and saves intact
Update 1.7 moves RimWorld from Unity to Ludeon Studios’ Waylith Engine. The studio says it runs two to four times faster, and existing saves and most mods still work.
Thélyson Orélien denies using AI to write novel, admits plagiarism
The Canadian-Haitian author says no sentence in his novel was created by AI, but apologized for plagiarizing other writers’ work.
Thélyson Orélien denies that AI wrote any sentence of his novel, “C’était ça ou mourir.”
The Canadian-Haitian writer says he used tools for research but wrote the book himself.
He apologized and accepted responsibility for plagiarizing texts by established authors after moving to Canada.
He says he began writing the novel in Quebec in 2017 and finished a first draft in 2019.
TNA ends Max Caster’s run after Riyadh attack reference at Bound for Glory
TNA said Max Caster will no longer wrestle for the company after his entrance rap at Bound for Glory referred to attacks in Riyadh. TNA apologized and removed the segment from replays and social media.
Wrestling Observer dated the attack at King Khalid International Airport in Riyadh to this day.
Caster performed an entrance rap referencing the Riyadh attacks before his match against Moose at Bound for Glory.
TNA announced Caster would no longer wrestle for the promotion and said it had removed the segment from replays and social media.
Raye manually reviews ticket sign-ups after 1.8 million apply for 5,000 seats
Raye says AI bots and scalpers overwhelmed sign-ups for her Royal Albert Hall show in London. Her team is manually selecting fans for presale access, with remaining tickets due to go on general sale.
- Sign-ups
- 1.8 million
- Venue capacity
- 5,000 seats
- Venue
- Royal Albert Hall, London
- Show date
- 23 October 2026
Collin Gosselin alleges abuse by mother Kate ahead of memoir release
Collin Gosselin says his mother, Kate, physically and emotionally mistreated him as a child. His memoir, “In the Shadow of Eight,” is due out Oct. 13.
Alleged treatment
Collin says his mother dragged him by the ear and mistreated him and his siblings.
Kate previously said reports of abuse were unfounded.
His placement in an institution
Collin says he was removed from the home and placed in an institution, with little contact with his family.
Kate said he was sent for treatment for educational and social challenges and that the decision was the best thing she could do for him.
Julianne Moore’s son Caleb Freundlich marries Kibriyaá Morgan
Caleb Freundlich and Kibriyaá Morgan have married after dating for nine years. His mother, actor Julianne Moore, shared the news on Instagram.
Amanda Seyfried says she is uncomfortable filming sex scenes for now
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RTL removes Unter Uns morning reruns ahead of planned end
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Apple announces Vision Pro horror film Remnants for October 16
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Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
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