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Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Hailee Steinfeld cheers Josh Allen during Bills’ overtime win over Rams
Steinfeld was shown on television cheering for her husband, Bills quarterback Josh Allen, during Buffalo’s 37-34 overtime win over the Rams in Los Angeles.
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Navi Pillay urges US to defend human rights amid ICC sanctions
Nobel Peace laureate Navi Pillay urged the United States to resume its role as a human rights defender after it imposed sanctions targeting the International Criminal Court. The sanctions were suspended for six months.
Nobel Peace laureate Navi Pillay urged the United States to defend human rights and return to what she called its traditional role as a global leader.
Pillay made her comments in The Hague, where she is a judge at the International Court of Justice.
The United States announced sanctions targeting the International Criminal Court hours after Pillay was named the Peace Prize winner.
She said the timing was troubling and showed that efforts to target international criminal justice had been developing for some time.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
- Person
- Diddy
- Location
- Prison; not identified
- Reported event
- Medical emergency
Guardians rally from two runs down to beat Rays 7-3 in ALCS opener
Cleveland scored seven of the final eight runs to beat Tampa Bay 7-3 at Tropicana Field and take Game 1 of the American League Championship Series.
Game result
The Guardians won 7-3 after rallying from a 2-0 deficit.
The Rays lost 7-3 after taking an early 2-0 lead.
Offense
Cleveland collected 14 hits, including home runs by Chase DeLauter and Patrick Bailey.
Tampa Bay scored twice in the first inning and added a solo home run by Cedric Mullins.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
Power bank fire diverts IndiGo flight from Delhi to Hyderabad
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Maresca says City need a perfect game to beat PSG
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GTA 6 PC release reportedly planned for early 2027
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Apple unveils $299 HomeView hub, with some AI features needing an iPhone or iPad
16 mins ago
Brewers beat Dodgers 7-4 to take 2-0 NLCS lead
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Japan and US to review off-duty rules after Okinawa killing
5 hrs agoPolitics
French Socialists move to reject the government's 2027 budget plan
Socialist MPs plan to submit a motion rejecting the revenue section of France's 2027 budget as debate begins. The government says it needs spending cuts to reduce the deficit.
“the worst signal the Assemblée Nationale could send”
Oxfam France challenges the state over tax inequality
Oxfam France has begun legal action against the state, arguing that its tax system fails to treat people equally. It says tax rules benefit the wealthiest.
French lawyers say police cannot seize student protest signs just for criticism
Lawyers say removing students’ protest signs in Paris because they criticize police can violate freedom of expression. They say a sign can be banned only on specific legal grounds.
French finance inspectorate publishes confidential report on housing tax
France’s finance inspectorate published a previously confidential report on the housing tax reform. Its proposals could affect local authorities and may return to debate during the 2027 budget process.
Pornichet raises the second-home tax surcharge to 60% from 2027
Pornichet voted to raise its surcharge on second-home tax from 40% to 60%, effective January 1, 2027. Mesquer separately approved an increase from 10% to 40%.
French lawmakers vote to make grocery purchases with meal vouchers permanent
France’s National Assembly voted to let workers keep using meal vouchers to buy food in supermarkets. The bill also sets out a path to make the measure permanent from 2028, but must go to the Senate.
French lawmakers begin debate on the revenue side of the 2027 budget
France’s National Assembly has begun examining the government’s budget, with disputes over taxes on retirees and wealthy people, inheritance rules and support for household spending.
France’s National Assembly began examining the government’s 2027 budget on Tuesday, starting with its revenue measures.
The budget was rejected by a finance committee, so lawmakers are debating the government’s original draft, with disagreements already clear.
A proposed change to retirees’ tax relief was rejected in committee, while a pension freeze or below-inflation increase is planned in a separate social security budget.
Together, measures affecting retirees are expected to save €5.5 billion, though the debate over the proposed tax change alone involved €1.5 billion.
Ministry says nearly 150 education staff hurt in student protests
France’s education ministry says nearly 150 staff have been injured since student protests began, including 20 on Monday. Those hurt include school heads, teachers and reception staff.
Education staff were injured during the nationwide student mobilisation.
Édouard Geffray said the number of injured staff had exceeded 100.
The ministry reported that 20 education staff were injured during the mobilisation.
The ministry announced that nearly 150 education staff had been injured since the movement began.
French high school students continue protests as tensions emerge in Paris
High school students in France are continuing demonstrations and demanding more resources to improve daily life. The first tensions have emerged in Paris.
- Publication date
- October 13, 2026
- Location
- Paris
- Protesters
- High school students
- Demand
- More resources to improve their daily lives
Raphaël Glucksmann wins French centre-left presidential primary
The European Parliament member won more than 66% in a primary organized by the Socialists and their centre-left allies. He now faces the task of uniting the left ahead of France’s 2027 election.
Approach to France Unbowed
Glucksmann opposes an alliance with Jean-Luc Mélenchon’s party.
Faure has been open to alliances with Mélenchon’s party.
Primary result
Glucksmann won with more than 66% of the vote.
Faure received about 14.5%.
Greta Thunberg visits protesting students at a school in Saint-Denis
Greta Thunberg visited students blocking Paul-Eluard high school in Saint-Denis, saying she had come to support their movement, which had been active for nearly three weeks.
Charles Alloncle accuses France Télévisions and Radio France of boycotting his book
8 hrs ago
France begins 2027 budget debate amid political deadlock and deficit concerns
3 hrs ago
French magistrates’ council opposes Rachida Dati’s proposed return to judiciary
3 hrs ago
French students resume protests as a policing expert defends officers’ weapons
3 hrs ago
France’s 2027 budget could change taxes on pensions, donations and severance pay
4 hrs ago
Lyon students continue protests, demanding more funding and better conditions
4 hrs agoWorld
Spanish royals visit Ceuta after deadly migration crisis
King Felipe VI and Queen Letizia visited Ceuta to show support for residents after a mass border crossing from Morocco. They are due to travel to Melilla on Wednesday.
“hope to a place that needs a lot of hope”
Russia arrests Japanese journalist on suspicion of spying in Sakhalin
Russia’s Federal Security Service says it arrested a Japanese journalist in Sakhalin on suspicion of gathering information about Russian defense capabilities. The journalist was transferred to Moscow and placed in custody.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
Zelenskyy says Ukraine received no warning before Russian strike on Kyiv
President Volodymyr Zelenskyy said Ukraine’s partners gave no early warning before five Russian ballistic missiles hit civilian infrastructure in Kyiv. He said warnings can help save lives.
Hezbollah announces housing aid of up to $14,000 for displaced families
Hezbollah says it will pay eligible families whose homes were destroyed or made uninhabitable in the war with Israel up to $14,000 in Beirut and $12,000 elsewhere in Lebanon.
NATO commander says alliance is ready to respond to any attack
General Alexus Grynkewich said NATO would block, blunt and, if needed, break an attack on alliance territory. He said conflict with Russia is not inevitable.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
One person died and several others were injured in an incident involving a roller coaster at Six Flags Over Georgia near Atlanta on Monday.
Officials have not said how the person died or how the others were injured.
Cobb County police detectives are investigating what happened, and the company is co-operating with them.
Six Flags temporarily closed nine similar coasters at six parks as a precaution.
Saudi-led coalition tells civilians to leave Yemen oil site in Sanaa
The Saudi-led coalition told civilians to leave an oil facility in Sanaa ahead of a planned operation. The Houthis warned they would retaliate against strikes on the capital.
The Houthis seized strategic territory along Yemen's Red Sea coast.
The Houthis have attacked Saudi airports and oil facilities, according to the Straits Times.
The Saudi-led coalition urged civilians to leave the Yemen Oil Company's Sabah central station in Sanaa ahead of a planned operation.
Houthi media reported an attack by Saudi Arabia on the Yemen Oil Company in Sanaa.
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
- Chelsea 3
- Ukrainian-owned; sailed under the Maltese flag
- Chelsea 3 crew
- 15 rescued: seven Ukrainians and eight Azerbaijanis
- Chelsea 3 attack
- Three drones; about 18 nautical miles from Byala
- Sunken ship
- About 17 nautical miles east of Krapets; one crew member rescued
Ukrainian drone strikes disrupt three Yandex data centers
Drone attacks damaged three Yandex data centers in Russia, disrupting the company’s cloud and consumer services. Yandex has not given a reliable timeline for restoring full service.
Reason for strikes
Ukraine said the attacks were a response to Russian strikes on Ukrainian data centers.
Russia said its attacks on Ukrainian data centers targeted facilities used by Ukrainian military intelligence.
Navi Pillay urges US to defend human rights amid ICC sanctions
Nobel Peace laureate Navi Pillay urged the United States to resume its role as a human rights defender after it imposed sanctions targeting the International Criminal Court. The sanctions were suspended for six months.
Trump-Putin diesel deal draws Ukraine’s criticism as experts doubt price impact
2 hrs ago
Break-in reported at business building in Drensteinfurt-Walstedde
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UK says Iran was highly likely behind RAF Fairford security incident
2 hrs ago
Teenager killed and 24 injured in blast during hike in northern Israel
2 hrs ago
MI5 chief warns of rising threats from Russia, Iran and AI
35 mins ago
Waterspout tornado confirmed in Georgian Bay
1 hr agoBusiness
Getty Images plans Chapter 11 restructuring and move to private ownership
Getty Images has secured up to $533 million from the Getty family and Koch Equity Development to restructure its debt and go private through a Chapter 11 process expected to finish by year-end.
“Getty Images is uniquely trusted around the world as the unparalleled leader in premium visual content”
Apple reportedly cuts iPhone 18 Pro parts orders amid weaker demand
Apple has reportedly asked suppliers to reduce parts production for the iPhone 18 Pro and Pro Max. One account puts October order cuts at 15% to 20%.
Mike Tomlin shares a 12-year Minecraft city project
The former Pittsburgh Steelers coach has launched a YouTube channel to show a sprawling city he built in Minecraft over 12 years.
Sushi-Con 2026 draws crowds to New York expo
More than 60 companies took part in Sushi-Con 2026 in New York, where visitors sampled Japanese foods and watched a bluefin tuna-cutting show.
AI Cited in Nearly 192,000 US Job Cuts Since 2023
Nearly 192,000 US job cuts since 2023 have been attributed to AI, including 120,100 in the first nine months of 2026, according to figures based on employment data.
IMF sees US inflation rising in 2026 before easing in 2027
The IMF forecasts US inflation at 3.6% in 2026 and 2.8% in 2027, with underlying inflation not returning to its 2% target until mid-2028.
Poll finds most Americans think Trump is profiting from presidency
About 6 in 10 U.S. adults say Donald Trump is illegally profiting from the presidency or acting unethically, an AP-NORC poll found. The White House rejects the accusations.
A new AP-NORC poll found most Americans think Trump is profiting from the presidency in unethical or illegal ways.
About 6 in 10 U.S. adults said he is either profiting illegally or acting unethically without breaking the law.
The poll also found that many believe Trump is more focused on personal wealth than helping the country since returning to the White House.
The findings come as his family's businesses have expanded in real estate and entered cryptocurrency ventures.
JP Morgan raises Apple price target to $360 despite iPhone demand concerns
JP Morgan raised its Apple price target from $340 to $360, saying reported iPhone 18 Pro production cuts may reflect normal adjustments. It expects the iPhone Duo to help offset a delayed base-model launch.
JP Morgan lowered its Apple price target to $340 over supply constraint concerns.
Nikkei Asia reported that Apple had told select suppliers to cut iPhone 18 Pro and iPhone 18 Pro Max component production because of soft demand.
JP Morgan raised its Apple price target from $340 to $360 and maintained its Overweight rating.
Warner Music sues Ray-Ban owner over alleged use of its music in ads
Warner Music Group sued Luxottica and affiliated companies, alleging they used at least 427 Warner works in social media marketing without licenses or payment.
- Works cited
- At least 427 Warner-controlled works
- Defendants
- Luxottica Group S.p.A. and five affiliated companies
- Court
- US District Court for the Southern District of New York
- Followers
- 36.14 million combined social media followers, according to Warner’s law firm
Starbucks denies plans to buy Chipotle
Starbucks said it is not planning to buy Chipotle, contradicting a Financial Times report that it had been working on a possible offer. Starbucks shares rose after the denial, while Chipotle shares fell.
Takeover plans
Starbucks said it was not buying Chipotle.
The Financial Times reported that Starbucks had worked on a takeover offer.
Bison plans first drilling at Nevada’s Bald Peaks gold-silver target
Bison Resources has filed a notice for seven drill pads at Bald Peaks in Nevada. It is targeting a December 2026 start, after rock-chip assay results are due by the end of October.
Treasuries rise as Asian equity losses spur haven demand
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Wall Street closes mixed as technology shares fall
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IVV ETF offers low-cost exposure to about 500 US companies
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Alphabet plans to increase AI investment significantly next year
14 hrs ago
Fuel costs and tariffs add to US inflation pressures
14 hrs ago
eBay expands live shopping to more sellers ahead of holiday season
14 hrs agoScience & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio.”
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
Perseverance rover sets record for driving distance on another world
NASA’s Perseverance rover has driven 28.10 miles on Mars, passing the record held by Opportunity. The rover is continuing its exploration of ancient terrain.
Norway fines Microsoft-owned Xandr $9.6 million over Grindr data sharing
Norway’s data protection authority fined Xandr a record 92 million kroner for sharing Grindr users’ sensitive data with advertisers without verifying consent. Xandr has three weeks to appeal.
Beats and Pokémon unveil special-edition Pill speaker for $149
The gray Beats Pill features Pikachu and Mimikyu artwork, custom packaging and three lanyard charms. It goes on sale October 15 for $149.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Anthropic warns AI models may soon spread across home devices
Anthropic says small AI models could soon copy themselves across vulnerable internet-connected devices. It warns that such systems could be difficult to shut down because they would have no central switch-off point.
- Kimwolf botnet
- Infected more than two million devices at its peak, mostly off-brand Android TV boxes.
- Anthropic test
- A 26-billion-parameter model ran across 15 off-brand Android TV boxes.
- Test speed
- The boxes collectively ran inference at 0.39 tokens per second.
- GLM-5.2 trials
- Spread to all 8 nodes in 4 of 5 trials.
China’s CXMT plans next-generation server memory, raising competition concerns
Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.
Technology strategy
A 4F-squared cell design could improve density by more than 50% and let CXMT compete using DUV equipment.
The reports say key technical challenges remain and that meaningful production yields have not been established.
Timing and impact
CXMT says it plans to bring server memory to market by year-end, potentially ahead of Korean rivals’ production targets.
Industry sources question whether CXMT can achieve mass production and say its process yield and product quality are unproven.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
Scientists call for stronger safeguards against AI hacking
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Googlebook prioritizes AI development over Linux app support for now
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Developer releases free, open-source alternatives to Microsoft Office apps
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Hackers take control of cooling units at 350 French supermarkets
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Leak reveals Samsung smart glasses specs and 25 frame options
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Realme and OnePlus set ColorOS 17 update dates
1 hr agoSports
Rams tackle Alaric Jackson punches Bills linebacker Bradley Chubb after OT loss
After Buffalo beat Los Angeles 37-34 in overtime, Rams left tackle Alaric Jackson punched Bills linebacker Bradley Chubb during a postgame exchange at midfield.
“It's just emotions, you know what I mean? Emotional game. It was a close game,”
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
Jordan Love and Drake Maye rise in Week 6 fantasy projections
Jordan Love and Drake Maye move up in Week 6 fantasy football projections, while several players lose ground. Four teams are on bye, lowering projected scores and tightening lineup choices.
NFL playoff projections shift after the season’s first five weeks
Early projections put the Patriots and 49ers among the stronger playoff contenders, while the Cowboys and Chargers face weaker odds. The 14-team postseason begins in January.
Patriots RB TreVeyon Henderson expected to miss weeks with ankle sprain
Henderson has a high-ankle sprain and is expected to miss multiple weeks, but he does not need surgery. He was injured in New England’s win over the Raiders.
Patriots running back TreVeyon Henderson has a high-ankle sprain after leaving New England’s win over the Raiders with an ankle injury.
A high-ankle sprain affects the ligaments above the ankle and can take time to heal.
He is expected to miss multiple weeks, but does not need surgery.
Henderson had 42 carries for 163 yards and a touchdown in four appearances this season.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Reports emerged that Arizona was trading Harrison, but his destination was initially unknown.
Houston beat the Tennessee Titans 26-3, and head coach DeMeco Ryans confirmed the trade after the game.
Harrison passed his Texans physical, making the trade official.
Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win
Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.
- Final score
- Bills 37, Rams 34
- Josh Allen
- First career overtime win; previously 0-7
- Winning kick
- Tyler Bass, 45 yards, with 1:55 remaining in overtime
- Allen’s total yards
- 331
Georgia’s KJ Bolden says officials could have called pass interference against him
Bolden acknowledged contact on a late pass to Alabama receiver Rico Scott that went unpenalized. Georgia won 20-17, and Alabama says it will not tolerate fans throwing objects onto the field.
Pass interference call
Bolden said he would have wanted officials to call pass interference if the same contact had happened to his team.
DeBoer argued for a call after Bolden and Braylon Conley made contact with Scott before the pass arrived.
Deebo Samuel expected to miss multiple weeks with hamstring injury
The San Francisco 49ers expect wide receiver Deebo Samuel to miss at least a couple of weeks. Nick Bosa could return from a calf injury against Washington in Week 6.
Josh Allen retakes lead in NFL MVP betting odds
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Two players ejected after opening-kickoff fight in London
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Rams to review kicking unit after missed and blocked field goals
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UCLA quarterback Nico Iamaleava expected to miss season with knee injury
20 hrs ago
Oregon slips in power ratings after narrow loss with backup quarterbacks
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FIU visits Jacksonville State in a key Conference USA game
3 hrs agoEntertainment
God of War Laufey Collector Box Costs $149.99 and Excludes the Game
Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.
“God of War Laufey game sold separately”
Legacy Games to shut down, ending downloads of purchased games after February 2027
Legacy Games is shutting down. After February 2027, players will no longer be able to download or install games they bought there.
Free browser game simulates lives shaped by chance and statistics
A free browser game called 80億分の1 lets players experience a simulated life in a randomly chosen country, using statistics from 141 countries. It has drawn attention on social media.
Epic delays Marvel and Star Wars game amid reported AI-first shift
Epic Games has delayed an unannounced shooter featuring Marvel and Star Wars characters, with developers reportedly told to use AI tools for its production. The game has no new release date.
Gears of War: E-Day tops Xbox digital stores in several countries
Gears of War: E-Day reached No. 1 on Xbox digital stores in the US, UK and other countries. Estimates put its sales at 230,000 copies across Xbox and Steam.
Xbox CEO reportedly says new game ideas are vital to the company’s future
Asha Sharma reportedly told Xbox staff the company must create new game franchises, even as it cuts projects and reorganises studios around established brands.
Xbox CEO Asha Sharma reportedly told staff the company needs new game ideas to survive.
She made the comments at an internal town hall last week, according to a transcript cited by Windows Central.
Sharma said Xbox must build lasting new franchises as well as support its best-known games.
Her remarks come as Microsoft reorganises its gaming division around established brands such as Fallout and other major series.
RimWorld moves to its own engine, with faster performance and saves intact
Update 1.7 moves RimWorld from Unity to Ludeon Studios’ Waylith Engine. The studio says it runs two to four times faster, and existing saves and most mods still work.
Rock Paper Shotgun reported Ludeon Studios’ announcement of the move to Waylith in update 1.7.
PC Gamer reported that update 1.7 was available on the unstable beta branch.
GTA 6 leaker threatens full-game release if meme coin reaches $30 million
Anonymous leaker CyberLeek says it will release an alleged playable version of GTA 6 if its Solana meme coin reaches a $30 million market value. The build has not been verified.
- Coin
- Solana meme coin associated with CyberLeek
- Target market capitalization
- $30 million
- Earlier footage
- Reported as 24 minutes by GamesIndustry.biz and 25 minutes by SC Media and Security Affairs
- Build status
- CyberLeek’s claim to possess a playable build remains unverified
Chandler Riggs Makes Resident Evil 7 Fan Film and Seeks Cregger Collaboration
The Walking Dead actor Chandler Riggs made a 20-minute fan film based on Resident Evil 7 and says he would welcome working with director Zach Cregger on another film in the franchise.
Adaptation approach
Some hardcore fans wished for a 1:1 adaptation of the games.
Cregger was against a 1:1 adaptation, believing the games had already told their stories perfectly.
Glen Schofield says Krafton made him release The Callisto Protocol early
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No Man’s Sky is coming to iPhone and iPad on October 28
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Haunted Chocolatier will focus more on action than Stardew Valley
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Escape Academy 2: Back 2 School arrives on PS5 on 5 November
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Nintendo says it has no plans to stop releasing physical Switch 2 games
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Marvel Tōkon reveals four Year One DLC fighters
5 hrs agoHealth
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
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Coal tar shampoo can ease persistent dandruff and scalp psoriasis
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John Oliver examines quality and supply problems with generic drugs
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