Trending
SpaceX lists CRS-35 mission
SpaceX published a page titled “CRS-35 Mission.” It provides no further details.
Diddy Taken Out of Prison After Medical Emergency
Diddy was rushed out of prison after a medical emergency. No further details were provided.
Six Flags closes nine coasters after fatal incident in Georgia
One person died and several were injured in an incident involving a coaster at Six Flags Over Georgia. Six Flags closed nine similar rides at six parks while authorities investigate.
“We are deeply saddened by the guest incident at our park today”
Trump’s diesel deal with Russia draws anger from European allies
A U.S. diesel agreement with Russia has angered European officials. Ukraine’s president questioned Washington’s motives, while European allies said they would maintain pressure on Moscow.
Questions raised about presidential runs by Rubio, Ossoff and Ocasio-Cortez
A headline asks whether Rubio, Ossoff and Ocasio-Cortez will run for president. It gives no answer or further details.
Social Security’s 2027 cost-of-living increase forecast at 3.5%
A forecast puts Social Security’s 2027 cost-of-living adjustment at 3.5%, which would add about $68 a month to the average retiree’s benefit. The official figure is due Oct. 14.
Japan and US to review off-duty rules after Okinawa killing
Japan and the United States will review rules for US troops’ off-base conduct after a Marine was arrested on suspicion of killing a woman in Okinawa.
A US Marine was arrested on suspicion of killing an Okinawan woman at a hotel in Naha, the prefectural capital.
He has denied the allegations, and the case remains under investigation.
Japan and the United States have begun talks to review rules for troops off base and consider ways to prevent similar incidents.
The discussions will cover the military’s liberty policy, education and joint patrols by US forces and Japanese police.
Rays look to level ALCS against Guardians in Game 2
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS. The Rays host Game 2 on Tuesday, with Freddy Peralta set to start.
Cleveland beat Tampa Bay 7-3 in Game 1 of the ALCS.
The teams are scheduled to meet in Game 2 at 8 p.m. ET.
Hailee Steinfeld Shares Update on Baby Harper Before Bills-Rams Game
Hailee Steinfeld shared a photo and details about baby Harper’s milestones in her newsletter ahead of the Buffalo Bills’ game against the Los Angeles Rams.
- Daughter
- Harper Haize Allen
- Newsletter
- Beau Society
- Newsletter date
- October 9
- New food
- Harper had started solids and liked them except for sweet potato.
Rwanda signs 10-year deal to bring Formula 1 back to Africa
Formula 1 has agreed a 10-year deal for Rwanda to host the African Grand Prix in the early 2030s. A new circuit in Bugesera must be built and meet FIA requirements first.
Purpose of the deal
Kagame said the partnership could bring jobs, skills, tourism and business opportunities. Formula 1 described it as a long-term commitment with a vision for meaningful impact.
Critics have labeled Rwanda’s sports sponsorship policy sportswashing.
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
Power bank fire diverts IndiGo flight from Delhi to Hyderabad
16 hrs ago
Maresca says City need a perfect game to beat PSG
3 hrs ago
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
53 mins ago
Judge halts tree removal at Washington golf course project
18 hrs ago
First look shows Michael B. Jordan and Austin Butler in Miami Vice reboot
22 hrs ago
Brazilian axé singer Netinho dies at 60
37 mins ago
Politics
Japan’s prime minister plans to question Agriculture Minister Yanagi by phone
The prime minister said she wants Agriculture Minister Yanagi to explain by phone tonight about an issue involving a shuttle bus.
“I want to receive a report by phone by the end of tonight”
Japan PM says he may dismiss farm minister if illegality is found
Japan's prime minister said he would not hesitate to dismiss the farm minister if illegality is found.
Japan considers including railways in defense-related spending
Japan is considering counting railway upgrades as defense-related spending in revisions to three security documents due by year-end. The goal is to help move supplies and equipment during emergencies.
Takaichi to finalize Japan’s foreign resident policy by March
Takaichi plans to finalize Japan’s foreign resident policy by March, taking population projections into account as the country balances its need for foreign workers with a shrinking population.
Debate over agriculture minister's future continues as LDP seeks to calm tensions
Discussion in Japan's upper house over Agriculture Minister Yanagi's future is drawing attention as the LDP tries to ease tensions. Discontent remains inside and outside the party.
Oita to begin collecting lodging tax in June 2027
Oita Prefecture will charge guests a nightly tax based on room rates from June 1, 2027, with revenue intended to support tourism and local municipalities.
Komeito’s new chief calls for political realignment
Komeito leader Okamoto said he wants the party to unite lawmakers who share similar values and serve as a focal point for political realignment.
Komeito leader Okamoto called for political realignment.
He said he wants the party to become a rallying point for lawmakers with similar values.
His goal is to build a bloc of like-minded lawmakers.
The statement describes a political aim, not a completed alliance.
Farm minister Kazuo Yana accused of election violation
Opposition parties questioned the prime minister about newly appointed farm minister Kazuo Yana’s January election campaign, amid accusations of an election violation.
Kazuo Yana’s election campaign took place.
Opposition parties questioned the prime minister about the campaign and her policies.
Japanese lawmakers divided over nuclear submarine study in security documents
Lawmakers are split on whether Japan's security documents should include a study of nuclear submarines. Defense Minister Shinjiro Koizumi said the public understands the need for discussion.
- Country
- Japan
- Defense minister
- Shinjiro Koizumi
- Publication date
- October 13, 2026
- Security issue
- Study of nuclear submarines in security documents
Ichikawa mayor admits giving wrong reason for denying mosque prayers in park
Ichikawa Mayor Koh Tanaka acknowledged that he wrongly said a former neighbor moved because of the mosque. The city had denied the mosque permission to hold holiday prayers in a municipal park.
Permission
The city denied permission, saying it could not be certain the event would not interfere with public use of the park.
The congregation sought permission to hold group prayers in the park for an Islamic holiday.
Japan seeks tenfold increase in Cabinet public relations budget
The Takaichi administration requested 7.2 billion yen for public relations in fiscal 2027, about 10 times the previous year's budget. Critics warn the spending could promote the government rather than provide balanced information.
Opposition calls on Japan’s farm minister to resign over scandals
8 hrs ago
Kishida urges caution on tax breaks for Japanese government bonds
10 hrs ago
Japan considers separate quota to restart foreign meal-service worker intake
11 hrs ago
JCP draft manifesto voices concern over revival of militarism
12 hrs ago
Japan aims to improve care workers’ treatment in 2027 fee revision
13 hrs ago
Japan lawmakers begin debate on tax cuts and new benefit plan
16 hrs ago
World
Drones hit two ships off Bulgaria; one sinks and 11 crew are missing
Two cargo ships were hit by drones in the Black Sea off Bulgaria. One sank, leaving 11 crew members missing, while all 15 people aboard the other ship were rescued.
“This is absolutely unacceptable: yet another attack in close proximity to Bulgaria’s territorial waters”
Nuremberg airport suspends flights after aviation emergency alert
Nuremberg airport in Germany suspended flights after an unclear aviation emergency was reported. Police said an aircraft landed safely, and the cause is under investigation.
Two Turkish citizens detained in Germany over fire at Polish Starlink station
German police detained two Turkish citizens suspected of setting fire to a Starlink station in central Poland. Polish officials say they will face sabotage charges in Poland.
Court orders new hearing in case over passport error that stopped family’s Thailand trip
A passport error listing a child’s sex incorrectly stopped a Krasnodar family from travelling to Thailand. A court overturned earlier rulings and sent the compensation case back for a new hearing.
Hezbollah to offer up to $14,000 to Lebanese families with destroyed homes
Hezbollah says it will pay eligible Lebanese families whose primary homes were destroyed or made uninhabitable in the war with Israel, with payments spread over a year.
Polish foreign minister says a European army could form by 2030
Radosław Sikorski said a joint European force could be formed by 2030, possibly limited to the Baltic states and the eastern flank.
MI5 chief warns Iran and Russia are stepping up threats to Britain
MI5 chief Ken McCallum said Iran is seeking to target harder sites, including military locations, while Russia is increasing hybrid operations against Ukraine’s allies. He also warned that AI could help terrorists develop biological weapons.
MI5 chief Ken McCallum warned of growing state threats to Britain in a speech in London on Tuesday.
He said Iran had shifted towards targeting harder sites, including military locations, although he could not discuss an investigation into a suspected plot involving RAF Fairford.
British Prime Minister Andy Burnham said Tehran was highly likely to be behind that suspected plot, but Iran has denied involvement.
McCallum said Iran-linked operations had led to more than 50 arrests over the past year.
Eight people injured in stabbing at Incheon supermarket
A man stabbed eight people at a supermarket in Incheon, South Korea. Police detained the suspect and are investigating the attack.
A man attacked people with knives while moving on an escalator in the supermarket building.
Shoppers subdued the suspect, and police arrested him.
France boards Russia-linked tanker in Indian Ocean
French forces boarded the DF Peak, a sanctioned oil tanker suspected of using a false flag and carrying fuel illicitly. The vessel is being escorted to Réunion for further checks.
- Vessel
- DF Peak
- Location
- More than 450 nautical miles south of Réunion
- Flag
- Benin
- EU sanctions status
- Listed among the EU-sanctioned ships
UK says Iran was highly likely behind RAF Fairford security incident
Prime Minister Andy Burnham said Iran’s Revolutionary Guard almost certainly directed a suspected plot near RAF Fairford. Britain has sanctioned two people and says further sanctions may follow.
Responsibility
Burnham said the incident was highly likely to have been coordinated in Iran and almost certainly directed by the IRGC.
Iran rejected any suggestion it was involved and called the accusation unfounded and malicious speculation.
Evidence
British authorities cited their assessment and said investigators found accelerants but no viable explosives in vans.
Iran called on Britain to present evidence supporting its allegations.
Zelensky says Russian strikes violated Trump’s proposed energy ceasefire
Zelensky says Russian attacks hit Ukrainian energy facilities after Trump announced a mutual pause in such strikes. Russia has not confirmed agreeing to the ceasefire.
Israel turns back Ethiopian Airlines cargo flight over Indonesian pilot
1 hr ago
Japan and US to review off-duty rules after Okinawa killing
3 hrs ago
One killed in GC-2 crash as second collision snarls traffic near Las Palmas
29 mins ago
Russian drone strike on Rivne university injures 20
1 hr ago
Spanish royals visit Ceuta after deadly migration crisis
2 hrs ago
Zelenskyy says Ukraine received no warning before Russian missile strike on Kyiv
1 hr ago
Business
TotalEnergies promises diesel price cuts from early November
The company says diesel prices for private drivers will fall by 8 to 12 cents per litre, and non-road diesel by 20 cents, after France releases strategic stocks.
“La fourchette donnée par le premier ministre pour nous sera plutôt de 8 à 12, donc d’une dizaine de centimes”
Fonderie de Bretagne faces liquidation after no takeover offer is confirmed
No buyer confirmed an offer for Fonderie de Bretagne, putting its Caudan factory and 244 jobs at risk of liquidation. A commercial court in Lorient is expected to rule on Thursday.
French debt and political instability unsettle financial markets
France’s rising debt, large budget deficit and political uncertainty have pushed up borrowing costs and weakened the euro. Marine Le Pen has signalled support for greater budget discipline.
No takeover offers for Fonderie de Bretagne before deadline
No takeover offers were submitted for Fonderie de Bretagne by Monday’s deadline, according to a French lawmaker. The court is expected to order liquidation on Thursday unless there is a last-minute change.
BYD considers France for one of two planned European factories
BYD executive Stella Li said the Chinese automaker plans to build two more factories in Europe. France is on its shortlist, and the company is closely assessing the possibility of a plant there.
Orange.fr suspends article comments while it works to restore the feature
Orange.fr suspended comments on its articles from 29 September 2026. Readers can no longer read or post messages, while the team works to restore the feature.
Record number of investors avoids France’s stock market
A record number of investors are avoiding the French stock market. No reason or further details are provided.
A record number of investors are avoiding France’s stock market.
The available information does not say how many investors this involves or when the change occurred.
It gives no reason for investors’ decisions.
It also does not identify which investors or parts of the market are affected.
Drone deliveries from France to Alderney under study
DragonFlyPads and Alderney’s Chamber of Commerce are studying whether drones could deliver goods, including urgent medical supplies, from Cherbourg to the island.
DragonFlyPads and Alderney Chamber of Commerce explored the viability of drone deliveries to the island.
The chamber said it was reviewing islanders’ responses on feasibility and potential demand.
French state to become Eramet’s largest shareholder
France will increase its stake in struggling mining group Eramet and take part in a planned €500 million capital increase, becoming its largest shareholder.
- Capital increase
- €500 million
- Eramet 2025 net loss
- €477 million
- Duval family stake at end of 2025
- 37.22%
- French state stake at end of 2025
- A little over 27%
Agirc-Arrco pension increase expected from 1 November after 2025 freeze
About 14 million private-sector retirees are expected to receive a higher Agirc-Arrco pension from 1 November. Negotiators will set the increase on 14 October, with estimates ranging from 1.2% to 1.9%.
Fonderie de Bretagne heads toward liquidation with no takeover offers
No takeover offer has been filed for Fonderie de Bretagne in Morbihan, and the foundry is heading toward liquidation.
Rennes airport aims to reach one million passengers by 2030-31
6 hrs ago
Stellantis presents nine concept cars at the Paris Motor Show
1 day ago
Bouygues Telecom and iBASIS sign international services partnership
7 hrs ago
ABP shifts €29 billion from US bonds to European debt, excluding France
8 hrs ago
France’s startup focus may overshadow small-business owners
8 hrs ago
BFM Business segment asks whether a golden rule could protect public finances
8 hrs ago
Science & Tech
Apple announces HomePod mini 2 with Siri AI and new sound features
Apple unveiled the HomePod mini 2, its first refresh of the speaker since 2020. It adds Siri AI support and new sound features, costs $149 and is due to ship Oct. 30.
“HomePod mini 2 brings together Siri AI, gorgeous new colors, and incredible audio”
China’s CXMT plans next-generation server memory, raising competition concerns
Chinese chipmaker CXMT says it plans to release server memory using a new DRAM design by year-end. Experts say mass-production quality and yields remain unproven.
GitLab fixes maximum-severity flaw that could let attackers run server code
The flaw could let attackers run code on affected GitLab servers without logging in. GitLab urges users of self-managed systems to install patched versions.
Ledger links CryptoBilis wallet implants to confirmed crypto thefts
Ledger says all confirmed losses involve devices sold through Southeast Asian reseller CryptoBilis. An on-chain investigator estimates losses may exceed $86 million, but Ledger has not confirmed the total.
NASA’s Perseverance rover sets record with 45.2km driven on Mars
Perseverance has driven 45.2km on Mars, surpassing the previous record held by NASA’s Opportunity rover. NASA says the rover’s autonomous navigation system handles more than 90% of its driving.
Scientists call for stronger safeguards against AI hacking
An international group of scientists, including dozens of Canadians, is urging stronger safeguards for AI models after several reported hacking incidents.
Apple announces a $299 Apple TV 4K with hands-free Siri and remote tracking
The new Apple TV 4K adds an A19 chip, built-in microphones for hands-free Siri and a remote with Find My. It goes on sale Nov. 13 for $299.
Apple announced a new Apple TV 4K at a smart home-focused event on Oct.
13.
The streaming box looks much like its predecessor, last updated in 2022, but has an A19 chip and Wi-Fi 7 support.
Built-in microphones let users talk to Siri hands-free, without speaking into the remote or a HomePod.
Apple unveils smart home devices made with LG and Schneider Electric
Apple introduced cameras, a doorbell, a lock, thermostats and sensors developed with LG and Schneider Electric for its smart home ecosystem.
Apple unveiled the Apple Home Collection in collaboration with LG Electronics and Schneider Electric.
Availability of the lineup is scheduled to begin.
Some accessories are expected to launch.
Cyberattack disrupts IT systems at three TFG London fashion brands
The Foschini Group says a cyberattack affected systems at Phase Eight, Hobbs and Whistles in the UK. Stores remain open, but some online services and orders may be delayed.
- Affected brands
- Phase Eight, Hobbs and Whistles
- Incident identified
- Sunday, 11 October 2026
- Stores
- Remained open
- Other UK brands
- Inside Story and White Stuff were unaffected
Honeybee stingers keep pumping venom after detaching from the insect
Researchers at Macquarie University filmed detached honeybee stingers pumping venom into a gel that mimics skin. Their findings reveal how the stinger’s tiny valves and lancets keep the venom flowing.
Sony Announces Japan-Only Midnight Black PlayStation 5
Sony will release a matte-black PS5 Digital Edition in Japan on Nov. 19 for ¥55,000. Buyers will need a separate disc drive to play physical games.
SpaceXSI bundles X Premium, Grok and Cursor in one subscription
49 mins ago
Ahold Delhaize takes some systems offline after cyberattack
2 hrs ago
Pacific buoy recorded a 17.6-metre rogue wave nearly three times its neighbours
4 hrs ago
Dwarf Fortress creator Tarn Adams says he does not plan to use generative AI
57 mins ago
CISA adds five exploited software flaws amid China-linked espionage concerns
1 hr ago
Meta launches Muse Wonder AI models aimed at catching up with rivals
5 hrs ago
Sports
Bills beat Rams 37-34 in overtime as Josh Allen earns first OT win
Josh Allen led Buffalo to a 37-34 overtime win over Los Angeles, his first career victory in overtime. The Bills improved to 4-1, while the Rams fell to 2-3.
“That's the beautiful thing about football: You get another drive.”
FIU visits Jacksonville State in a key Conference USA game
Florida International visits Jacksonville State on Oct. 13 with both teams unbeaten in Conference USA play. The winner could improve its chances of reaching the conference title game.
49ers linebacker Dre Greenlaw ejected after headbutting Seahawks player
Dre Greenlaw was ejected in the second quarter against Seattle after a late hit on quarterback Sam Darnold led to a sideline confrontation and a headbutt to Ernest Jones IV.
Model backs Penn State and Auburn against the spread in Week 7
A computer model recommends Penn State to cover against Michigan and Auburn to cover against Georgia in Week 7. It simulates each FBS game 10,000 times.
Marvin Harrison Jr. trade to Houston becomes official after physical
Harrison passed his physical and is now a Houston Texan. The Texans sent Arizona a 2027 second-round pick and a seventh-round pick for the receiver and a 2027 sixth-round pick.
Titans stick with Cam Ward as they face a 2027 quarterback decision
Tennessee coach Robert Saleh says Cam Ward will not be benched after the Titans fell to 0-5. His early numbers raise questions about whether the team may draft another quarterback in 2027.
49ers lead Week 6 NFL power rankings as several 0-5 teams struggle
The 49ers remain No. 1 in one Week 6 ranking, while the Vikings rise and the 0-5 Chargers, Titans and Dolphins sit near the bottom.
Two Week 6 rankings assess the NFL after five weeks of the 2026 season.
One list keeps the San Francisco 49ers at No.
1, with the Kansas City Chiefs second and the Jacksonville Jaguars third.
The other ranking also puts the 49ers at the top and highlights the strength of the NFC West.
Jaguars left tackle Anton Harrison to have knee surgery
Anton Harrison will have arthroscopic surgery on his right knee after an injury against Philadelphia. His absence could last three to five weeks or the rest of the regular season.
Harrison injured his knee during Jacksonville’s 19-17 win over Philadelphia in London.
Reports said Harrison was set to have arthroscopic knee surgery, with his recovery timeline still uncertain.
Harrison is expected to have surgery when the Jaguars return from London.
The Jaguars are scheduled to play Houston at Wembley Stadium, with Walker Little expected to start at left tackle.
Dolphins and Browns lead NFL teams relying on rookies
After five weeks, Miami had 14 first-year contributors, while Cleveland rookies had played 1,401 snaps. The Ravens, Giants and Chargers also ranked among the top five teams in rookie playing time.
- Dolphins
- 14 first-year contributors, described as a near-record pace
- Browns
- 1,401 rookie snaps
- Giants
- 1,246 rookie snaps
- Chargers
- 1,301 rookie snaps
Penix says he hopes to play next week after rib injury
Atlanta quarterback Michael Penix Jr. left the Falcons’ overtime loss to Baltimore with a rib injury. He said he hopes to return next week, but further tests are planned.
Rams lose to Bills and look to reset before facing Cardinals
The Rams lost 37-34 to the Bills, leaving them 2-3 despite gaining 454 yards. Puka Nacua said the team must regroup and define its identity before hosting Arizona.
Two players ejected after opening-kickoff fight in London
1 day ago
Rams to review kicking unit after missed and blocked field goals
10 hrs ago
Rams' limited investment in special teams faces renewed scrutiny
2 hrs ago
Commanders and Giants tie 27-27 after Washington runs out of time in overtime
1 day ago
UCLA quarterback Nico Iamaleava expected to miss season with knee injury
19 hrs ago
Penix’s rib injury is not considered serious, but Falcons return remains uncertain
12 hrs ago
Entertainment
Selma Blair charged with assault after flight incident in New York
Selma Blair faces two second-degree assault charges over alleged attacks on a police officer and a nurse after a Delta flight landed at JFK. She was released on bail and has a court hearing scheduled for January.
“This was not an intentional assault.”
God of War Laufey Collector Box Costs $149.99 and Excludes the Game
Sony’s U.S. collector box for God of War Laufey costs $149.99 and includes merchandise, but no game disc or download code. It is due out with the game on Feb. 16, 2027.
Bryan Cranston mourns Breaking Bad co-star RJ Mitte, who died at 34
Cranston paid tribute to Mitte, who played his son on Breaking Bad, remembering his acting and disability advocacy. Accounts differ on whether his death was officially confirmed as suicide.
IDFA to open with film following Myanmar resistance recruits
The 39th International Documentary Film Festival Amsterdam will open with “White Tiger Column,” following young recruits as they train with Myanmar’s resistance movement. The festival runs Nov. 12 to 22.
The Social Reckoning opens to $5.5 million, far below its predecessor
Aaron Sorkin’s follow-up to The Social Network took in $5.5 million in its domestic opening weekend, against a reported production budget of about $30 million to $42 million.
RimWorld moves to its own engine, with faster performance and saves intact
Update 1.7 moves RimWorld from Unity to Ludeon Studios’ Waylith Engine. The studio says it runs two to four times faster, and existing saves and most mods still work.
Thélyson Orélien denies using AI to write novel, admits plagiarism
The Canadian-Haitian author says no sentence in his novel was created by AI, but apologized for plagiarizing other writers’ work.
Thélyson Orélien denies that AI wrote any sentence of his novel, “C’était ça ou mourir.”
The Canadian-Haitian writer says he used tools for research but wrote the book himself.
He apologized and accepted responsibility for plagiarizing texts by established authors after moving to Canada.
He says he began writing the novel in Quebec in 2017 and finished a first draft in 2019.
TNA ends Max Caster’s run after Riyadh attack reference at Bound for Glory
TNA said Max Caster will no longer wrestle for the company after his entrance rap at Bound for Glory referred to attacks in Riyadh. TNA apologized and removed the segment from replays and social media.
Wrestling Observer dated the attack at King Khalid International Airport in Riyadh to this day.
Caster performed an entrance rap referencing the Riyadh attacks before his match against Moose at Bound for Glory.
TNA announced Caster would no longer wrestle for the promotion and said it had removed the segment from replays and social media.
Raye manually reviews ticket sign-ups after 1.8 million apply for 5,000 seats
Raye says AI bots and scalpers overwhelmed sign-ups for her Royal Albert Hall show in London. Her team is manually selecting fans for presale access, with remaining tickets due to go on general sale.
- Sign-ups
- 1.8 million
- Venue capacity
- 5,000 seats
- Venue
- Royal Albert Hall, London
- Show date
- 23 October 2026
Collin Gosselin alleges abuse by mother Kate ahead of memoir release
Collin Gosselin says his mother, Kate, physically and emotionally mistreated him as a child. His memoir, “In the Shadow of Eight,” is due out Oct. 13.
Alleged treatment
Collin says his mother dragged him by the ear and mistreated him and his siblings.
Kate previously said reports of abuse were unfounded.
His placement in an institution
Collin says he was removed from the home and placed in an institution, with little contact with his family.
Kate said he was sent for treatment for educational and social challenges and that the decision was the best thing she could do for him.
Julianne Moore’s son Caleb Freundlich marries Kibriyaá Morgan
Caleb Freundlich and Kibriyaá Morgan have married after dating for nine years. His mother, actor Julianne Moore, shared the news on Instagram.
Amanda Seyfried says she is uncomfortable filming sex scenes for now
3 hrs ago
Taylor Swift’s ‘Patient Zero’ holds the No. 1 spot on the Hot 100
39 mins ago
God of War Laufey Collector’s Box Will Not Include the Game
1 hr ago
RTL removes Unter Uns morning reruns ahead of planned end
3 hrs ago
Apple announces Vision Pro horror film Remnants for October 16
1 hr ago
Hugh Grant backed out of replacing Charlie Sheen on Two and a Half Men
58 mins ago
Health
Early research links GLP-1 drugs to signs of slower biological aging
Early research suggests GLP-1 drugs may affect biological aging, but experts say the evidence is not strong enough to use them solely in hopes of living longer.
“My concern is that people could overread some of this stuff.”
UCLA specialists outline how doctors can choose between two MASH drugs
A UCLA-led review offers an algorithm to help doctors choose between resmetirom and semaglutide, the first two FDA-approved drugs for adults with MASH and moderate to advanced fibrosis.
Bimatoprost eye lens shows early promise for cataracts and glaucoma
A lens containing the glaucoma drug bimatoprost showed early promise in a randomized comparison with standard glaucoma therapy for people with cataracts and glaucoma.
Italian Registry Study Finds Avacopan Appeared Effective for AAV
An Italian registry study found that avacopan appeared strongly effective for ANCA-associated vasculitis, though the finding may not settle concerns about the treatment.
Inclisiran lowered LDL cholesterol more than bempedoic acid in a trial
In a study of 402 adults at high cardiovascular risk, inclisiran reduced LDL cholesterol more than bempedoic acid after 150 days. Similar overall rates of side effects were reported in both groups.
European groups issue guidance on two MASH treatments
Three European medical groups recommend considering resmetirom or semaglutide for some adults with non-cirrhotic MASH and significant liver fibrosis, alongside lifestyle changes and careful monitoring.
Syndax ends Niktimvo development for lung disease after Phase 2 failure
Syndax is ending development of Niktimvo for idiopathic pulmonary fibrosis after the treatment failed a mid-stage trial.
Syndax is ending development of Niktimvo as a treatment for idiopathic pulmonary fibrosis, or IPF.
IPF is a rare lung disease.
The treatment failed a Phase 2 trial, a mid-stage study of a medicine.
The result means Syndax will not continue developing Niktimvo for this disease.
Experts raise safety concerns about Neurocrine’s Prader-Willi drug
Vykat XR has been linked to seven deaths and nearly 100 hospitalizations since its approval, though case reports do not prove the drug caused them. Some experts are urging its withdrawal.
Vykat XR was approved to treat Prader-Willi syndrome.
An open letter about potential safety issues tied to the drug was released.
STAT reported growing alarm among patient advocates and some experts.
US FDA supports planned trial of StemSmart therapy for Crohn’s disease
The FDA supported most elements of NeuroScientific Biopharmaceuticals’ proposed phase two trial of its StemSmart cell therapy. The company aims to start the study in Australia and the US by the end of 2026.
- FDA response
- Positive responses to six of seven Pre-IND questions
- Earlier study
- 18 patients; 78 per cent overall clinical response rate
- Remission
- 44 per cent of patients in the earlier study
- Planned trial
- Phase two, in Australia and the US
Bristol Myers lung drug succeeds at lower dose, but higher dose misses target
Bristol Myers Squibb said admilparant slowed lung function decline in a Phase 3 trial of people with idiopathic pulmonary fibrosis, but only the lower dose met the main goal.
Dose response
The high-dose result was confounding and the lack of dose response raised questions about the drug's profile.
The lower-dose success could open a major commercial opportunity despite lingering questions.
Mirum reports late-stage trial success for Livmarli in rare liver diseases
Mirum Pharmaceuticals said Livmarli significantly reduced cholestatic pruritus in a late-stage trial involving ultra-rare liver diseases.
Bristol Myers reports two Phase 3 trial successes
23 hrs ago
Aficamten Improves Exercise Capacity in Nonobstructive Heart Condition Trial
23 hrs ago
GLP-1 drugs may have a role in addiction care, but questions remain
1 day ago
Coal tar shampoo can ease persistent dandruff and scalp psoriasis
1 day ago
John Oliver examines quality and supply problems with generic drugs
1 day ago