Health · Fitness & Nutrition · 1 day ago
Dermatologist weighs evidence for collagen, peptides and PDRN in skin care
Dermatologist Mamina Turegano discussed skin-care ingredients with doctor and host Mark Hyman on his show.
She said there is evidence that collagen supplements may help, but some favorable studies had industry support.
She explained that collagen peptides do not go straight to the skin; they may signal the body to make its own collagen.
Topical peptides can be used in products such as serums and moisturizers, though their effects vary and are not equivalent to Botox.
Turegano said most data on PDRN, a compound she described as derived from salmon sperm, concerns injections, while evidence for creams is less strong.
She stressed that supplements and skin products do not replace sun protection, sleep, exercise, a healthy diet and stress management.
She recommended establishing basic skin care first, including cleansing, moisturizing and sunscreen, before adding ingredients such as peptides.
Dermatologist Mamina Turegano said collagen peptides may have benefits, while warning that they are not a stand-alone solution for skin ageing.
She said some studies with favourable results on collagen had industry support.
Turegano said sleep, sun protection, exercise, diet and stress management should take priority over supplements or serums.
She described topical peptides as ingredients that may signal cells to produce more collagen or increase hydration.
She said most data on PDRN concerns injections, while evidence for topical formulations is less solid.
- Who
- Dermatologist Mamina Turegano discussed the ingredients with doctor and host Mark Hyman.
- What
- They discussed evidence and limits for collagen peptides, topical peptides and PDRN in skin care.
- When
- The article was published on 2026-10-11; the interview date was not stated.
- Where
- The discussion took place on The Dr. Hyman Show.
- Why
- Hyman asked whether collagen supplements have supporting data or are only about appearance.
This story does not have two clearly opposing sides.
This story does not have a timeline yet.
- Dermatologist
- Mamina Turegano
- Host
- Mark Hyman
- Outlet
- Infobae
- Publication date
- 2026-10-11
- PDRN
- Polydesoxyribonucleotide, described as derived from salmon sperm
- Research caveat
- Some favourable collagen studies had industry support
What people are saying
In general, yes, I think there is enough data to support taking collagen
Taking collagen peptides does not mean that collagen goes directly to the skin
I would prefer someone to sleep better, use sun protection, reduce stress and strength train before adding collagen peptides
Most of the data on PDRN concerns injections into the skin
Sources
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