3 weeks ago

Scientists identify 'motivation cells' that keep us working for rewards

Scientists identify 'motivation cells' that keep us working for rewards
‘Motivation cells’ discovered: Scientists identify neurons that help us keep working for rewards · indianexpress.com

Scientists in Japan found a special group of brain cells that help us keep going when a task is hard.

These cells are called orexin neurons, and they are also known for helping with sleep and appetite.

The scientists studied rats that had to touch a screen many times to get food.

When the rats expected food, these brain cells became very active.

If the rats did not get the food they expected, the cells stayed active.

When scientists turned the cells on, the rats worked harder and for longer.

When the cells were switched off, the rats gave up much sooner.

This means these cells act like a 'keep going' switch in the brain.

The discovery might one day help people who struggle to stay motivated, such as those with depression or ADHD.

Key facts

Research institution
Nagoya University, Japan
Publication
Proceedings of the National Academy of Sciences (PNAS)
Lead researchers
Associate Professor Hiroyuki Mizoguchi and Professor Emeritus Kiyofumi Yamada
Neurons studied
Orexin neurons, known for regulating sleep, appetite, and energy balance
Animal model
Genetically engineered 'orexin-Cre' rats
Key experiment
Progressive ratio test requiring increasing touchscreen responses for food rewards
Key measure
Breakpoint, the point at which an animal stopped trying
Potential implications
Depression, ADHD, and substance addiction

Sources

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