1 month ago

GLP-1 Drugs Risk Muscle Loss Without Proper Guidance

GLP-1 Drugs Risk Muscle Loss Without Proper Guidance
GLP-1 drugs like Ozempic, Mounjaro may cause muscle loss without proper guidance, warn experts · firstpost.com

Scientists in India say that medicines called GLP‑1, like Ozempic and Mounjaro, can help people lose weight and protect their hearts.

But if people take them without a doctor’s help, they might lose muscle instead of just fat.

The doctors made a guide that says you should eat enough protein, drink plenty of water, and do strength exercises while on these medicines.

They also warned that people should not use these drugs just to look slimmer.

The guide is special for Indians because they usually have less muscle and eat more simple carbs.

The doctors hope that by following the guide, people can keep their muscles strong and stay healthy.

Key facts

Drug names
Ozempic (semaglutide), Mounjaro (tirzepatide)
Muscle loss risk
25-40% of weight loss may be lean body mass
Protein recommendation
1.2-1.5 g/kg body weight during therapy
Target population
Indian patients
Consensus source
Journal of the Association of Physicians of India (JAPI)

Quotes

Dr. Shashank Joshi

Endocrinologist and expert involved in the consensus

“"Most people focus on losing fat, but far fewer pay attention to preserving muscle. Yet, up to 25 percent of the weight lost with GLP‑1‑based therapies can come from lean body mass, making muscle preservation a critical aspect of obesity management."”
firstpost.com
“"GLP‑1 medicines are highly evidence‑based drugs with proven benefits apart from weight loss, including protection of the heart and kidneys. They should be prescribed under expert medical supervision and not used simply for cosmetic weight loss."”
firstpost.com

Sources

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