1 week ago
Lung Cancer Is Rising Among People Who Never Smoked
Lung cancer can happen even to people who have never smoked.
Smoking is still the biggest known risk, but it is not the only one.
Pollution, smoke from other people, indoor cooking fires and some workplace materials may also raise risk.
Family history and changes in a person’s genes may matter too.
Doctors say lung cancer in never-smokers can be biologically different from cancer linked to smoking.
Some of these cancers may respond to medicines that target specific genetic changes.
Warning signs include a cough that lasts, trouble breathing, chest pain, coughing blood and unexplained weight loss.
These symptoms can look like ordinary illnesses, so they should not be ignored when they persist or return.
Doctors may use a chest X-ray and sometimes a CT scan to investigate unexplained symptoms.
National Institutes of Health studies cited in the article estimate that one in four lung cancer cases worldwide occurs among never-smokers, while a doctor cites a 15%–20% estimate.
Smoking remains the largest risk factor, but air pollution, second-hand smoke, biomass-fuel smoke, radon, asbestos, silica and diesel exhaust are also linked to risk.
Never-smokers’ lung cancers may involve specific genetic alterations and can respond well to targeted treatments when mutations are identified.
Women, younger patients, people with a family history, and those exposed to pollution or occupational hazards may face elevated risk.
Persistent cough, breathlessness, chest pain, coughing blood, weight loss, recurring infections, hoarseness or fatigue should prompt medical evaluation.
- Who
- Never-smokers who develop lung cancer, along with doctors and researchers discussing their risks and treatment.
- What
- The article examines the increasing recognition of lung cancer among never-smokers and the genetic and environmental factors associated with it.
- Where
- Worldwide, with India reporting nearly 60,000 lung cancer deaths annually and the highest prevalence in its North-East region.
- When
- The article says more than one million people die from lung cancer worldwide each year; a cough lasting more than three weeks is identified as a warning sign.
- Why
- Experts attribute cases among never-smokers to factors including genetic susceptibility, air pollution, second-hand smoke, biomass-fuel smoke, radon and occupational exposures.
Key facts
- Global annual deaths
- More than 1 million people die from lung cancer worldwide each year.
- Deaths in India
- Nearly 60,000 people die from lung cancer in India annually.
- Never-smoker estimate
- The article cites an NIH estimate that one in four worldwide lung cancer cases occurs in never-smokers.
- Alternative estimate
- A pulmonary-medicine consultant cited in the article estimates that 15%–20% of lung cancer patients worldwide have never smoked.
- Additional risk factors
- Air pollution, passive smoking, biomass-fuel smoke, radon, asbestos, silica and diesel exhaust are identified as risks.
- Warning signs
- Persistent cough, breathlessness, chest pain, coughing blood, unexplained weight loss, recurring chest infections, hoarseness and fatigue.
Quotes
Dr Vikas T. Talreja
Senior Consultant in Medical Oncology at Regency Health
“Strong scientific evidence links long-term exposure to air pollution, passive smoking, indoor smoke from biomass fuels, radon exposure, and occupational hazards such as asbestos, silica, and diesel exhaust with an increased risk.”
deccanchronicle.com
“Though smoking is still the biggest risk factor for lung cancer, there is a noticeable increase in cases among never-smokers”
deccanchronicle.com








