Health · Medical Research · 4 hrs ago
Study links several health issues to early-onset Alzheimer’s years before diagnosis
A Finnish study found several health issues were more common before early-onset Alzheimer’s diagnoses.
Researchers compared health records for 407 people diagnosed before age 65 with records for more than 4,000 people without progressive neurodegenerative disease.
The differences appeared as far as 15 years before diagnosis, and were strongest in the five years beforehand.
The more common conditions included vertigo, depression, headaches, brain injuries, thyroid disorders, alcohol-related disorders, epilepsy and stroke.
The study did not find higher rates of high blood pressure or high cholesterol, conditions often linked to late-onset Alzheimer’s.
Early-onset Alzheimer’s accounts for up to 10% of Alzheimer’s cases, and the reasons for these health patterns are not clear.
The findings do not mean these symptoms prove someone has Alzheimer’s, but experts advise discussing multiple unusual symptoms with a health care provider.
A study found that several health issues were more common among people later diagnosed with early-onset Alzheimer’s disease.
The conditions could appear as many as 15 years before diagnosis, and were most pronounced in the five years beforehand.
The analysis compared 407 people with early-onset Alzheimer’s disease with data from more than 4,000 people without progressive neurodegenerative disease.
The researchers did not find higher rates of high blood pressure or high cholesterol among those later diagnosed.
Experts cautioned that the symptoms do not prove someone has early-onset Alzheimer’s, and the reasons for the reported links remain unclear.
- Who
- Researchers studied 407 people with early-onset Alzheimer’s disease and compared them with more than 4,000 people without progressive neurodegenerative disease.
- What
- The study found several health issues were more common before an early-onset Alzheimer’s diagnosis.
- When
- The researchers examined the 15 years before diagnosis; the conditions were most pronounced in the five years beforehand.
- Where
- Participants with early-onset Alzheimer’s had visited one of two memory clinics in Finland.
- Why
- The study examined health issues that might be linked to early-onset Alzheimer’s before diagnosis. The reasons for the links are not yet clear.
This story does not have two clearly opposing sides.
The study examined health issues recorded during this period before participants were diagnosed with early-onset Alzheimer’s disease.
The differences in several health issues were most pronounced during this period.
Interactions with the healthcare system increased markedly.
- Study participants
- 407 people with early-onset Alzheimer’s disease
- Comparison group
- More than 4,000 people without progressive neurodegenerative disease
- Study setting
- Two memory clinics in Finland
- Period examined
- 15 years before diagnosis
- Vertigo
- 5.9% of early-onset Alzheimer’s patients versus 2.1% of the general population
What people are saying
Most previous studies have focused on late-onset Alzheimer’s disease, and considerably less is known about early-onset Alzheimer’s disease.










