Sports · American Football · 15 hrs ago
Seahawks favored to beat unbeaten 49ers in Week 5 matchup
The Seattle Seahawks host the San Francisco 49ers on Sunday in an NFL Week 5 game at Lumen Field.
San Francisco is 4-0, while Seattle is 3-1 and has scored at least 30 points in three straight games.
The teams are division rivals, and Seattle beat San Francisco 41-6 in last season’s Divisional Round before going on to win the Super Bowl.
The 49ers’ quarterback, Brock Purdy, has the league’s highest passer rating and has not been sacked this season.
Seattle’s defense has allowed the fewest total and passing yards per game, and no opposing starting quarterback has thrown for 200 yards against it this season.
San Francisco is also dealing with injuries on both sides of the ball.
The prediction is that Seattle will win by more than three points, but the game will determine whether the 49ers’ unbeaten start continues.
The Seattle Seahawks are favored to beat the unbeaten San Francisco 49ers in a Week 5 matchup.
San Francisco is 4-0, while Seattle enters the game at 3-1.
The game is scheduled for Sunday, Oct. 11, at Lumen Field in Seattle.
Fox Sports cites Seattle’s strong defense and offense, as well as injuries to the 49ers, in backing the Seahawks to cover the spread.
- Who
- The Seattle Seahawks and San Francisco 49ers.
- What
- The teams are scheduled to meet in a Week 5 NFL game.
- When
- Sunday, Oct. 11, 2026, at 4:25 p.m. ET.
- Where
- Lumen Field in Seattle, Washington.
- Why
- It is a Week 5 matchup between division rivals. Fox Sports’ prediction favors Seattle, citing its performance and injuries affecting San Francisco.
This story does not have two clearly opposing sides.
No direct quotes in the coverage so far.
Seattle beat San Francisco 41-6 in the Divisional Round.
The article lists betting odds for the matchup as of this date.
The Seahawks and 49ers are scheduled to play at 4:25 p.m. ET.
- San Francisco record
- 4-0
- Seattle record
- 3-1
- Seahawks moneyline
- -174
- Point spread
- Seahawks -3
- Game venue
- Lumen Field, Seattle, Washington
- Kickoff
- Oct. 11, 2026, at 4:25 p.m. ET
Sources
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