Banting and Macleod shared the 1923 Nobel Prize for insulin discovery

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  Frederick G. Banting and John J.R. Macleod shared the 1923 Nobel Prize in Physiology or Medicine for the discovery of insulin.

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  Their research was conducted at the University of Toronto in the early 1920s.

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  Insulin regulates blood glucose and became a treatment for diabetes, which was often fatal in severe forms before insulin therapy.

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  Charles Best assisted Banting with experiments, and biochemist James Collip helped purify insulin for clinical use.

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  In January 1922, insulin treatment produced a marked improvement in Leonard Thompson, a 14-year-old boy with severe diabetes, after the preparation was further purified.

Who

Frederick G. Banting and John J.R. Macleod.

What

They shared the 1923 Nobel Prize in Physiology or Medicine for the discovery of insulin.

When

The Nobel Prize was awarded in 1923; the research took place in the early 1920s.

Where

The University of Toronto.

Why

Their work established insulin as a treatment for diabetes.

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