Health · Medical Research · 1 hr ago
Researchers examined diet patterns and lung cancer in 95,612 US adults
Researchers examined diet and lung cancer in 95,612 US adults who took part in a US cancer screening trial.
The trial enrolled adults aged 55 to 74 at 10 screening centers between 1993 and 2001.
Researchers used a food questionnaire to calculate a score for a diet pattern linked to sulfur-metabolizing gut bacteria.
They treated the score as a proxy because the study did not measure participants’ gut bacteria or sulfur compounds directly.
The researchers wanted to test whether this eating pattern was associated with lung cancer diagnoses and deaths.
Smoking remains the main risk factor for lung cancer, but risk also varies among smokers, and lung cancer occurs in people who have never smoked.
The study examined whether diet might offer another clue about lung cancer risk, but the available findings do not state what association, if any, the researchers found.
Researchers examined whether a sulfur microbial diet score was associated with lung cancer incidence and lung cancer-related mortality.
The prospective cohort study included 95,612 participants in the US Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
The score used dietary questionnaire data to estimate adherence to a food pattern linked to sulfur-metabolizing gut bacteria.
Researchers monitored lung cancer incidence through 2009 and lung cancer-related deaths through 2018.
The available article text does not report the study’s results.
- Who
- Researchers studied 95,612 participants in the PLCO Cancer Screening Trial.
- What
- They examined associations between a sulfur microbial diet score and lung cancer incidence and related mortality.
- When
- The trial enrolled participants from 1993 to 2001. Outcomes were monitored through 2009 for incidence and 2018 for mortality.
- Where
- The United States, across 10 screening centers.
- Why
- To examine whether a microbiome-linked dietary pattern was associated with lung cancer incidence and mortality.
This story does not have two clearly opposing sides.
The PLCO trial enrolled approximately 155,000 US adults aged 55–74 across 10 screening centers.
Participants completed a 124-item dietary questionnaire used to derive the sulfur microbial diet score.
Researchers monitored lung cancer incidence.
Researchers monitored lung cancer-related mortality.
- Analytic cohort
- 95,612 participants
- Trial enrollment
- Approximately 155,000 adults
- Participant ages
- 55–74 years
- Screening centers
- 10 in the United States
- Diet questionnaire
- 124 items
- Diet score components
- 25 food groups
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