Archive · 2 Aug 2025
Dual-Medicine Combination Effective for High Blood Pressure
Scientists studied different pills with two medicines each to help people with high blood pressure.
They tested the pills on over a thousand people in India.
The pills worked well, lowering blood pressure for most people.
The study showed that using a single pill with two medicines is a safe and effective way to control high blood pressure.
Nearly 70% of patients were able to control their blood pressure.
The study can help doctors and policymakers choose the best treatments for people with high blood pressure.
AIIMS-led study found dual-medicine pills safe and effective for South Asians with hypertension.
The study compared amlodipine/perindopril, amlodipine/indapamide, and perindopril/indapamide combinations.
Over 1,200 patients in India participated in the trial across 32 hospitals.
All three combinations lowered blood pressure significantly after six months.
Nearly 70% of patients achieved controlled blood pressure using the two-drug therapies.
- Who
- The study was led by AIIMS and involved over 1,200 patients with hypertension.
- What
- A study found that combining two blood pressure medications in one pill is safe and effective for South Asians.
- When
- The study's results were published in the journal Nature Medicine.
- Where
- The study was conducted in India across 32 hospitals.
- Why
- To determine the effectiveness of different two-drug combinations for treating high blood pressure in South Asians.
- Lead Institution
- AIIMS, New Delhi
- Participants
- Over 1,200 patients
- Location
- 32 hospitals in India
- Combinations Tested
- Amlodipine/perindopril, amlodipine/indapamide, perindopril/indapamide
- Blood Pressure Reduction
- Around 14/8 mmHg (24-hour), 30/14 mmHg (clinic)
- Success Rate
- Nearly 70% achieved controlled blood pressure