Archive · 23 Dec 2025
Men's Brains Age Faster Than Women's, Study Finds
A new study found that men's brains age faster than women's.
Researchers looked at brain scans from over 4,700 healthy adults and found that men's brains showed more decline in areas like touch, memory, and movement.
This is interesting because women are almost twice as likely to get Alzheimer's disease, a type of dementia.
Scientists thought this might be because women's brains age faster, but this study suggests that's not the case.
Instead, other factors like genes and hormones might play a bigger role.
For example, a gene called Kdm6a, which women have two copies of, might cause more inflammation in the brain after menopause.
So, while men's brains age faster, women's higher risk of Alzheimer's might be due to other reasons.
Men's brains show more rapid decline in volume and structure than women's.
The postcentral cortex declines 2% per year in men, compared to 1.2% in women.
Women's ventricles expand more rapidly, a marker of brain tissue loss.
The study challenges the theory that women's higher Alzheimer's risk is due to faster brain ageing.
Other factors like the Kdm6a gene and oestrogen levels may contribute to women's higher Alzheimer's risk.
- Who
- Researchers at the University of Oslo and an international team
- What
- Studied brain ageing differences between men and women
- When
- Over an average of 3 years
- Where
- Using MRI scans of 4,700 adults
- Why
- To understand why women have a higher risk of Alzheimer's disease
- Study Participants
- 4,700 adults aged 17-95
- Study Duration
- Average of 3 years
- Key Brain Region
- Postcentral cortex
- Annual Decline in Men
- 2% per year
- Annual Decline in Women
- 1.2% per year
- Alzheimer's Risk in Women
- Almost twice as likely
- Gene Linked to Inflammation
- Kdm6a
- Hormone Linked to Protection
- Oestrogen