Archive · 14 Jan 2026
Nobel Laureate Jack Szostak on Telomeres, Ageing, and Cancer
Telomeres are special sequences at the ends of chromosomes that help keep them intact.
Nobel Laureate Jack Szostak and his team discovered that telomeres play a crucial role in ageing and cancer.
Long-term stress can shorten telomeres, which can lead to cell death and contribute to ageing.
The team also found an enzyme called telomerase that can add DNA to telomeres, making them longer.
This research is important for understanding how to live healthier lives and develop treatments for diseases.
Szostak is also studying how life began on Earth, focusing on the first cells called protocells.
The Genome India Project is using this knowledge to create a genetic database of Indians to understand their health and history.
Telomeres are special genetic sequences at the ends of chromosomes that protect them and play a role in ageing and cancer.
Long-term stress can shorten telomeres, leading to cell death and contributing to ageing.
The enzyme telomerase adds DNA sequences to telomeres, counteracting the shortening that occurs during cell division.
Nobel Laureate Jack Szostak, along with Elizabeth Blackburn and Carol Greider, discovered the role of telomeres and telomerase.
The Genome India Project aims to create a genetic database of Indians to understand their health and history.
- Who
- Nobel Laureate Jack Szostak, along with Elizabeth Blackburn and Carol Greider
- What
- Discovery of telomeres and their role in ageing and cancer
- When
- Nobel Prize awarded in 2009, with initial discoveries in the 1980s
- Where
- Research conducted at various institutions, including the University of Chicago and University of California
- Why
- To understand the role of telomeres in ageing, cancer, and the origins of life
- Nobel Laureate
- Jack Szostak
- Discovery
- Telomeres protect chromosomes
- Impact of Stress
- Shortens telomeres, contributes to ageing
- Genome India Project
- Aims to create a genetic database of Indians
- Telomerase
- Enzyme that adds DNA sequences to telomeres
- First Evidence of Telomerase
- Discovered by Elizabeth Blackburn and Carol Greider in 1984
- Current Research Focus
- Origins of life and first cells (protocells)