Archive · 11 Sep 2026
Persistent High Blood Sugar May Require Diabetes Treatment Changes
Metformin is a medicine that helps the body use insulin better.
It also helps the liver make less sugar.
Sometimes, blood sugar can still stay high while someone takes it.
This does not automatically mean metformin has stopped working.
Type 2 diabetes can change over time.
The pancreas may gradually make less insulin.
Because of this, one medicine may no longer be enough.
A doctor may need to review the treatment and consider changes when glucose targets are not reached.
Blood sugar around or above 200 mg/dL while taking metformin does not necessarily mean the medicine has stopped working.
Metformin improves insulin sensitivity and reduces glucose production by the liver.
Type 2 diabetes can progress as the pancreas produces less insulin over time.
One medicine may eventually be insufficient to maintain good glucose control.
Dr. Pranav Ghody said treatment may need closer review and intensification when glucose targets are not met.
- Who
- Dr. Pranav Ghody, consultant endocrinologist and diabetologist at Wockhardt Hospitals, discussed the issue.
- What
- Persistent blood sugar around or above 200 mg/dL while taking metformin may indicate that diabetes treatment needs reassessment.
- When
- The article does not specify when the blood sugar readings or treatment change occurred.
- Where
- The comments were reported by indianexpress.com; Dr. Ghody works at Wockhardt Hospitals, Mumbai Central.
- Why
- Type 2 diabetes may progress, causing the pancreas to produce less insulin, while metformin primarily improves insulin sensitivity and reduces liver glucose production.
- Blood sugar level discussed
- Around or above 200 mg/dL
- Medicine
- Metformin
- How metformin works
- Improves insulin sensitivity and reduces glucose production by the liver
- Condition
- Type 2 diabetes
- Possible reason for persistent high glucose
- The pancreas may produce less insulin as diabetes progresses
- Potential treatment response
- A closer review and possible treatment intensification
- Expert cited
- Dr. Pranav Ghody, consultant endocrinologist and diabetologist