Archive · 26 Jan 2026
Circadian Rhythm Linked to Dementia Risk
A big study with over 2,000 people aged around 79 found that those with a strong internal body clock, called the circadian rhythm, had a much lower chance of getting dementia.
The circadian rhythm helps control sleep, hormones, and other daily processes.
People with weaker or more disrupted rhythms were more likely to develop dementia over three years.
Poor sleep, which is often linked to disrupted rhythms, has been suspected to contribute to both dementia and heart disease.
The study considered factors like heart health and blood pressure but not sleep apnoea.
Addressing physical inactivity and improving sleep quality might help reduce dementia risk.
The immune system and the removal of toxic proteins from the brain during sleep are also being studied.
However, it's still not clear if sleep disruption alone causes dementia or if it's part of a bigger picture involving lifestyle and health factors.
The study suggests that improving sleep is important, but more research is needed to understand its role in preventing dementia.
A 2025 study of 2,000 people aged 79 on average found that a strong circadian rhythm nearly halved the risk of dementia.
People with weaker or more disrupted circadian rhythms were more likely to develop dementia over three years.
Poor sleep, often linked to disrupted rhythms, has been suspected to contribute to both dementia and heart disease.
The study accounted for factors like heart health and blood pressure but not sleep apnoea.
Improving physical activity and sleep quality may help reduce dementia risk through multiple pathways.
- Who
- People with an average age of 79
- What
- A study on the link between circadian rhythm and dementia risk
- When
- 2025 study with a 3-year follow-up
- Where
- Not specified
- Why
- To understand the impact of circadian rhythm on dementia risk
- Study Size
- 2,000 people
- Average Age
- 79
- Follow-Up Duration
- 3 years
- Risk Reduction
- Almost halved for strong circadian rhythm
- Key Factors
- Sleep, heart health, blood pressure
- Potential Interventions
- Exercise, light exposure, sleep scheduling
- Sleep Duration and Dementia
- No clear independent risk factor
- Medications and Dementia Risk
- Benzodiazepines linked to increased risk