Archive · 21 Aug 2026
Blood Group Mismatch No Longer Blocks Kidney Transplants
Some people need a kidney transplant but cannot use a family member’s kidney because their blood groups do not match.
Doctors can now reduce the patient’s antibodies before the operation.
They may also use a treatment called plasma exchange.
These steps can help the body accept a kidney from a family member with a different blood group.
Dr PS Vali said that many willing donors were previously rejected for this reason.
He said the newer approach can have success rates similar to regular transplants.
Families are being encouraged to discuss all possible donors with transplant specialists.
Yashoda Hospitals says it has facilities for complex transplants and advanced dialysis treatments.
ABO-incompatible kidney transplants can allow patients to receive kidneys from mismatched family donors.
Nearly 30% of willing family donors were previously rejected because of blood group incompatibility.
Pre-transplant antibody reduction and plasma exchange are used before transplantation.
Reported success rates are comparable to those of conventional kidney transplants.
Dr PS Vali urged families not to reject potential donors prematurely.
- Who
- Dr PS Vali, Senior Consultant Nephrologist at Yashoda Hospitals, Secunderabad, discussed ABO-incompatible kidney transplants.
- What
- Blood group mismatch can be addressed through pre-transplant antibody reduction and plasma exchange, allowing some mismatched family members to donate kidneys.
- When
- The report does not specify when the statement was made.
- Where
- The statement was reported from Anantapur and referred to Yashoda Hospitals in Secunderabad.
- Why
- The approach aims to expand the pool of possible family kidney donors, since nearly 30% were previously rejected because of blood group incompatibility.
- Procedure
- ABO-incompatible kidney transplantation
- Previous donor rejection
- Nearly 30% of willing family donors were previously rejected because of blood group incompatibility.
- Preparation
- Pre-transplant antibody reduction and plasma exchange
- Reported outcome
- Success rates comparable to conventional transplants
- Specialist quoted
- Dr PS Vali, Senior Consultant Nephrologist
- Hospital
- Yashoda Hospitals, Secunderabad
- Other facilities mentioned
- HDF and CRRT dialysis procedures