Archive · 22 May 2025
Hospital-Made CAR-T Cell Therapy Shows Promise, Reduces Costs
Imagine your body has special cells that fight cancer.
Scientists can take these cells, train them to recognize cancer cells, and put them back in your body.
This is called CAR-T cell therapy.
A new study in India shows that this therapy can be made right at the hospital.
This makes it cheaper and faster.
The study found that it worked very well for some patients, even those who had tried other treatments.
This new method could help many more people get this life-saving treatment.
CAR-T cell therapy uses a patient's own cells to fight cancer.
The trial showed it could be safely manufactured and administered at CMC Vellore hospital in India.
The PoC approach reduced costs by approximately 90% compared to the global average.
The study included 10 patients with acute leukemia and lymphoma, who had failed other treatments.
Overall, eight of the ten patients remained cancer-free at a median follow-up of 15 months.
- Who
- Researchers at CMC Vellore, led by Dr. Vikram Mathews, conducted the trial.
- What
- A trial showed CAR-T cell therapy can be safely manufactured and administered in-hospital.
- When
- The study results were published on May 22, 2025.
- Where
- CMC Vellore hospital in India.
- Why
- To reduce costs, improve efficiency, and make CAR-T therapy more accessible.
- Therapy Type
- CAR-T Cell Therapy
- Location of Trial
- CMC Vellore, India
- Patient Ages
- 6-59 years
- Patients Treated
- 10
- Remission Rates for ALL
- 100%
- Remission Rates for LBCL
- 50%
- Cost Reduction
- Nearly 90% less than global average
- Production Time
- 9 days