Archive · 1 Aug 2025
Mounjaro Found Superior to Dulaglutide for Heart Health
Eli Lilly's drug Mounjaro (tirzepatide), originally for diabetes, helps with weight loss and may protect the heart.
A recent study showed Mounjaro lowers the risk of heart attacks, strokes, and death compared to another diabetes drug, dulaglutide.
This trial suggests Mounjaro helps people with diabetes and obesity have better heart health and live longer.
The drug works differently than older drugs and is becoming increasingly important in treating diabetes and obesity-related issues.
Mounjaro (tirzepatide) showed an 8% lower risk of major cardiovascular events than dulaglutide.
Tirzepatide reduced the risk of all-cause mortality by 16% compared to dulaglutide.
The trial included over 13,000 adults, evaluating heart health outcomes.
Tirzepatide slowed the decline of kidney function compared to dulaglutide.
The drug led to greater reductions in blood glucose levels and weight loss.
- Who
- The study involved over 13,000 adults.
- What
- A trial comparing the cardiovascular benefits of tirzepatide (Mounjaro) to dulaglutide.
- When
- The trial results were recently announced.
- Where
- The trial involved participants from over 30 countries.
- Why
- To assess the cardiovascular benefits of tirzepatide compared to dulaglutide in people with type 2 diabetes.
Focus on Weight loss and benefits
Drug efficacy and effects
Cardiovascular Benefits
Focus on Weight loss and benefits
Mounjaro has significant benefit against heart attack or stroke, and also improves blood glucose.
Drug efficacy and effects
Dulaglutide benefits focus more on blood sugar and weight-loss
- Drug Tested
- Mounjaro (tirzepatide) and dulaglutide
- Company
- Eli Lilly
- Participants
- Over 13,000
- Cardiovascular Events Reduction
- 8% lower risk with tirzepatide
- All-Cause Mortality Reduction
- 16% lower risk with tirzepatide
- Drug Class
- GLP-1 and GIP receptor agonist
Sources
Landmark head-to-head trial reveals cardiovascular benefits of Eli Lilly’s diabetes drug Mounjaro
Weight Loss Drug Mounjaro May Help Diabetics Live Longer, Protect The Heart & Kidneys: Eli Lilly
