Archive · 1 Sep 2025
Clopidogrel Superior to Aspirin in CAD: New Study Results
Doctors are studying clopidogrel, a medicine for people with heart problems.
Aspirin is often used, but new research suggests clopidogrel may be better.
Researchers looked at about 29,000 people with heart disease.
They found clopidogrel helped prevent heart attacks and strokes more than aspirin, without increasing the risk of bleeding.
The study showed people taking clopidogrel had a lower risk of heart problems.
This means clopidogrel might be a better choice than aspirin for many people with heart disease.
However, experts say it is important to speak with your doctor about switching medications.
Study showed clopidogrel is superior to aspirin in preventing heart attacks and strokes in CAD patients.
The study involved nearly 29,000 patients with coronary artery disease.
Clopidogrel reduced major cardiovascular events by 14% compared to aspirin.
Rates of major bleeding were similar between clopidogrel and aspirin.
Experts suggest clopidogrel may be preferred long-term antiplatelet therapy for CAD.
- Who
- Researchers and medical experts
- What
- Compared clopidogrel and aspirin for CAD treatment
- When
- Unspecified
- Where
- International study, reported at the European Society of Cardiology congress in Madrid
- Why
- To determine the effectiveness of clopidogrel versus aspirin
- Drug
- Clopidogrel
- Study Focus
- Coronary Artery Disease (CAD)
- Participants
- Nearly 29,000 patients
- Result
- Clopidogrel reduced heart/stroke risk by 14%
- Bleeding Risk
- Similar to aspirin
- Study Published
- The Lancet