Archive · 24 Dec 2025

New Monoclonal Antibody Shows Promise for Rare Liver Disease

New Monoclonal Antibody Shows Promise for Rare Liver Disease

Doctors found a new medicine called nebokitug that might help people with a rare liver disease called PSC.

This disease makes the liver ducts scarred and inflamed, which can be very serious.

The medicine is a special kind of antibody that stops a protein called CCL24, which causes inflammation and scarring.

In a test with 76 patients, the medicine was safe and helped reduce liver damage, especially in people with more advanced disease.

Right now, there's no good treatment for PSC, so this is exciting news for patients who need better options.

The medicine is given through an IV every few weeks, and doctors hope it can improve the lives of people with PSC.

Sources