Archive · 11 Dec 2025
Talk Therapy Effective for Depression, Study Finds
A new study found that slowly reducing the dose of antidepressants while receiving talk therapy can help people with depression stay well.
The study looked at 17,000 adults and found that this method prevents one relapse in every five people compared to stopping medication abruptly.
Doctors say that both medication and talk therapy are important, but the best approach depends on the individual.
Talk therapy takes time to show results but can be a good option for those who prefer not to take medication.
The study also warns against using antidepressants for loneliness in the elderly without a proper diagnosis.
A study in The Lancet Psychiatry found that slowly tapering antidepressants combined with psychological support can prevent one relapse in every five people.
The study involved 17,000 adults and examined antidepressant de-prescribing strategies up to April 2025.
Slow tapering with psychological support is as effective as continuing antidepressants at standard doses in preventing depression relapse.
Doctors emphasize that both medication and psychotherapy are effective, and the best approach should be tailored to each individual.
Talk therapy, such as cognitive behavior therapy (CBT), takes time to show results but can be a good option for those who prefer not to take medication.
- Who
- Adults with depression, particularly those who have experienced multiple episodes
- What
- A study on the effectiveness of slow tapering of antidepressants combined with psychological support
- When
- The study examined data up to April 2025
- Where
- The study was conducted by researchers from the University of Verona, University of Rennes, Universitaire de France, and the University of Padova
- Why
- To address concerns about overprescribing, long-term use, and withdrawal symptoms of antidepressants
- Study Source
- The Lancet Psychiatry
- Study Participants
- 17,000 adults
- Effectiveness of Slow Tapering
- Prevents one relapse in every five people
- Recommended Treatment Duration
- 6-9 months after first episode, up to 2 years for recurring episodes
- Treatment Options
- Antidepressants, psychotherapy, or a combination
- Psychotherapy Types
- Cognitive behaviour therapy (CBT)
- Study Lead Author
- Professor Giovanni Ostuzzi, University of Verona
- Psychiatrist Consulted
- Dr. Nishikant Thorat, B.J. Government Medical College