Archive · 27 Sep 2025
Paracetamol in Pregnancy: Autism Link Unproven, Guidelines Reaffirm
Some studies have looked at whether taking paracetamol (like Tylenol) during pregnancy could be linked to autism or ADHD in children.
These studies show mixed results.
The main thing is that taking paracetamol is considered safe, and the Australian government and medical professionals advise that pregnant women can safely take paracetamol to treat a fever.
A recent study found there was a marginally increased risk of autism, however, when comparing siblings with different exposures, researchers found no increased risk of autism.
It is very important to treat high fevers.
If you're pregnant and have a fever, talk to your doctor.
Paracetamol is commonly used to relieve pain and reduce fever during pregnancy.
Australia's Therapeutic Goods Administration reaffirms paracetamol's safety for pregnant women.
Studies have examined the association between paracetamol use and neurodevelopmental disorders.
A recent study suggests a marginally increased risk of autism and ADHD, but no risk among siblings with different exposures.
Experts recommend using the lowest effective dose of paracetamol for the shortest time and treating fever.
- Who
- Researchers, pregnant women, medical professionals
- What
- The association between paracetamol use during pregnancy and neurodevelopmental disorders, such as autism.
- When
- Research reviewed studies published from 1995 to 2024, with the most notable study published in 2024.
- Where
- Studies conducted internationally, including a large study in Sweden.
- Why
- To assess potential links between paracetamol and neurodevelopmental disorders in offspring, and to provide up-to-date advice to pregnant women.
Advice and Studies
Perspective on Guidelines
Safety of Paracetamol
Advice and Studies
There is no clear evidence paracetamol is harmful during pregnancy.
Perspective on Guidelines
Pregnancy and fever needs to be treated as risk factors
- Drug Name
- Paracetamol (Acetaminophen/Tylenol)
- Use
- Pain and fever relief during pregnancy
- Pregnancy Category
- Category A (safe for all stages)
- Recent Studies
- Some studies suggest possible links with autism and ADHD
- 2024 Study
- Marginally increased risk; no evidence in sibling pairs
- Expert Recommendation
- Use lowest effective dose, treat fevers.
