Archive · 11 Aug 2025
Study Pinpoints Potential Biomarker for Long Covid
Scientists may have found something in your blood that can show if you have long Covid.
They looked at tiny packages called EVs in the blood of people with long Covid.
Inside these packages, they found pieces of the Covid virus.
These pieces came from a special part of the virus called Pp1ab.
This is a unique protein found only in the virus, not in healthy cells.
This discovery could help doctors confirm if someone has long Covid and maybe even find new ways to treat it.
They are not sure yet if this means the virus is still making copies of itself in the body, but it does mean there is trash left from the virus.
More research is needed to fully understand this.
Researchers identified potential biomarker for long Covid.
The biomarker is SARS-CoV-2 protein fragments within extracellular vesicles (EVs).
Study analyzed blood samples from 14 patients over 12 weeks of exercise training.
Found 65 distinct SARS-CoV-2 protein fragments in the EVs of long Covid patients.
These fragments originate from the virus's Pp1ab protein.
- Who
- Researchers studied 14 long Covid patients.
- What
- Identified potential biomarker for long Covid using protein fragments.
- When
- The study was done over 12 weeks.
- Where
- The research was conducted at the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Centre.
- Why
- To develop better diagnostics and potential treatments.
Researchers' View
Uncertainties
Impact on Diagnostics and Treatment
Researchers' View
Researchers believe this new biomarker may lead to better diagnostics and treatments
Uncertainties
N/A
Virus Replication
Researchers' View
The peptides found in EVs could be 'trash' left over after viral protein formation
Uncertainties
It is currently unknown if the virus is still replicating itself.
- Research Focus
- Long Covid biomarker
- Biomarker Type
- SARS-CoV-2 protein fragments
- Location of Fragments
- Extracellular vesicles (EVs)
- Protein Source
- Pp1ab protein
- Study Duration
- 12 weeks
- Patient Count
- 14