Archive · 2 Nov 2025
COVID-19 in Pregnancy Linked to Higher Autism Risk in Children
Scientists studied babies whose moms got COVID-19 while they were pregnant.
They found that these babies had a slightly higher chance of having problems with how their brains developed, like trouble talking, autism, or moving their bodies, by the time they were three years old.
This might happen because the mom's sickness could affect how the baby's brain grows in the womb.
The risk was higher if the mom got sick later in her pregnancy.
Even though the risk is higher, the overall number of babies with these issues is still small.
This research shows it's important for pregnant people to try and avoid getting COVID-19.
COVID-19 infection during pregnancy is linked to a 29% higher risk of neurodevelopmental conditions in children by age 3.
Affected conditions include speech delays, autism, and motor disorders.
The study analyzed 18,124 mother-child pairs from March 2020 to May 2021.
Risk was highest when infection occurred during the third trimester and was greater in males.
Researchers suggest immune activation during pregnancy may disrupt fetal brain development, emphasizing the importance of preventing COVID-19 infection in pregnant individuals.
- Who
- Researchers from Mass General Brigham
- What
- COVID-19 infection during pregnancy may be associated with a higher risk of neurodevelopmental conditions in children by age 3, including autism and motor disorders.
- When
- March 2020 to May 2021
- Where
- US (Mass General Brigham)
- Why
- Potential disruption of foetal brain development due to immune activation during pregnancy.
- Study Population
- 18,124 mother-child pairs
- COVID-19 Exposure Group
- 861 mothers tested positive during pregnancy
- Control Group
- 17,263 mothers tested negative during pregnancy
- Neurodevelopmental Diagnosis Rate (COVID-19 group)
- 16.3% by age 3
- Neurodevelopmental Diagnosis Rate (Control group)
- 9.7% by age 3
- Associated Risk Increase
- 29% higher odds of neurodevelopmental condition
- Highest Risk Period
- Third trimester of pregnancy