Archive · 3 Sep 2025
Nasal Spray Shows Promise in Reducing COVID-19 Risk by 70%
Imagine a simple nasal spray, like the one you might use for allergies.
Scientists are studying if this spray, called azelastine, can also protect you from catching COVID-19.
The study found that people using the spray were much less likely to get infected with the virus.
Out of 450 adults, those using the spray got infected at a much lower rate than those who didn't.
This spray might offer an easy way to add extra protection.
It's available without a prescription in places like the US and Australia.
The most common side effects are a bad taste, occasional nosebleeds, and feeling tired.
The trial had some limitations like a smaller sample size, so scientists need to do more research.
Azelastine nasal spray reduced COVID-19 infections by approximately 70% in a clinical trial.
The study involved 450 healthy adults, most of whom were vaccinated.
Participants used the spray at least three times daily.
Researchers noted fewer symptomatic COVID-19 cases and overall respiratory infections in the azelastine group.
Common side effects include bitter taste, nosebleeds, tiredness and fatigue.
- Who
- Scientists from Saarland University in Germany conducted the trial.
- What
- Azelastine nasal spray was found to reduce COVID-19 infections by about 70% in a clinical trial.
- When
- The study is ongoing, with initial results released.
- Where
- The clinical trial took place at Saarland University in Germany.
- Why
- To evaluate the effectiveness of an over-the-counter nasal spray in preventing COVID-19 infection.
- Key Finding
- Azelastine nasal spray reduces COVID-19 infections by approximately 70%
- Study Participants
- 450 healthy adults (average age ~33), mostly vaccinated
- Spray Usage
- At least 3 times daily; up to 5 times daily if symptomatic or exposed
- Trial Location
- Saarland University, Germany
- Side Effects
- Bitter taste, occasional nosebleeds, tiredness/fatigue
- Availability
- OTC in US (Astepro Allergy) and Australia (Azep Nasal Spray)