Archive · 30 May 2025
Researchers Develop Colon-Targeted Drug Delivery System
Scientists have created a new way to deliver cancer medicine directly to the colon.
They used a natural resin called mastic gum to make tiny particles that carry the drug 5-fluorouracil (5-FU).
This drug is used to fight colon cancer.
The new particles protect the medicine until it reaches the colon, where it releases the drug slowly.
This helps the medicine work better and reduces harm to the rest of the body.
The particles are very efficient at carrying and releasing the drug where it's needed.
Researchers developed a colon-targeted drug delivery system for cancer treatment.
The system uses cross-linked nanoparticles from mastic gum, a natural resin.
The drug delivery system targets 5-fluorouracil (5-FU), a chemotherapy drug.
The formulation showed an 83.5% encapsulation efficiency and 95.2% drug release in the colon.
The approach aims to improve chemotherapy efficacy for colon cancer, reducing side effects.
- Who
- Researchers from Andhra Pradesh, India, with collaborators in Saudi Arabia and the UAE.
- What
- A colon-targeted drug delivery system.
- When
- The research was published in 'Nature Scientific Reports'.
- Where
- The research was conducted in Andhra Pradesh, India.
- Why
- To enhance chemotherapy efficacy and reduce systemic toxicity for colon cancer.
- Drug Delivery System
- Colon-targeted nanoparticles
- Material
- Mastic gum
- Drug
- 5-fluorouracil (5-FU)
- Encapsulation Efficiency
- 83.5%
- Drug Release in Colon
- 95.2%
- Particle Size
- 240 nanometres