Archive · 28 Sep 2025
Coffee and Medications: What You Should Know
Coffee, a common pick-me-up, can mix poorly with some medicines.
Some cold and flu medicines and coffee can both speed things up in your body, which can make you feel shaky or have a fast heartbeat.
Thyroid medicine, when taken with coffee, might not work as well.
Coffee can also make some medicines for depression and painkillers not work as well.
If you take any medication, check with your doctor about drinking coffee.
Caffeine, a stimulant, is found in coffee and many medications.
Combining caffeine with cold and flu medicines can cause jitters and other side effects.
Coffee reduces the effectiveness of thyroid medication if taken together.
Caffeine can make some antidepressants less effective.
Coffee combined with painkillers might increase risks of side effects.
- Who
- Experts
- What
- Warning about interactions between coffee and specific medications.
- When
- Not specified
- Where
- Not specified
- Why
- To inform the public about potential negative interactions and side effects.
- Caffeine Effect
- Stimulant that boosts energy and speeds up the central nervous system.
- Medication Interaction: Cold/Flu
- Combining caffeine with pseudoephedrine may cause jitters, headaches, rapid heart rate.
- Medication Interaction: Thyroid
- Coffee before levothyroxine reduces absorption and effectiveness.
- Medication Interaction: Antidepressants
- Caffeine can reduce the effectiveness of some antidepressants.
- Medication Interaction: Painkillers
- Combining with caffeine can speed absorption, increase side effect risks.