Archive · 5 Dec 2025
Chronic Kidney Disease Affects Men and Women Differently
A new study found that chronic kidney disease can make people's thinking skills worse over time, but it affects men and women differently.
Men with this disease have more problems with their thinking and their heart doesn't work as well as women with the same disease.
The researchers think this is because the connection between the kidneys, heart, and brain works differently in men and women.
This could help doctors find better ways to treat people with chronic kidney disease, especially if they pay attention to these differences between men and women.
The study was done by researchers at Marshall University and was published in a science journal.
Chronic kidney disease accelerates cognitive decline, with different effects in men and women.
Men with chronic kidney disease experience higher cognitive impairment and greater reduction in heart function.
The study suggests a stronger heart-brain link in men, leading to more severe cognitive effects.
Researchers propose sex-specific targets for early diagnosis and treatment.
The findings could prompt innovative pharmacological interventions tailored to sex differences.
- Who
- Researchers from Marshall University
- What
- Chronic kidney disease accelerates cognitive decline differently in men and women
- When
- Not specified
- Where
- Rural population in the US
- Why
- Due to damage to the heart-brain link triggered by chronic kidney disease
- Study Focus
- Cognitive decline in chronic kidney disease patients
- Key Finding
- Men experience higher cognitive impairment and heart function reduction
- Publication
- American Journal of Physiology-Heart and Circulatory Physiology
- Researchers
- Marshall University
- Population Studied
- Rural community-dwelling population in the US
- Lead Author
- Sneha S Pillai
- Lead Researcher
- Komal Sodhi