Archive · 25 Oct 2025
Semaglutide Shows Cardiovascular Benefits Beyond Weight Loss
Imagine a medicine called semaglutide.
Scientists did a big study and found that it helps people with heart problems, even if they don't lose much weight.
Semaglutide seems to protect the heart in other ways, like by shrinking the waistline, which reduces belly fat.
This is important because it lowers the chances of having a heart attack or stroke.
The medicine works by helping your body feel full, so you eat less.
Doctors now see that this medicine can help people with heart issues, and it might open doors to new treatments to prevent heart problems.
A new analysis confirms semaglutide lowers heart problems risk.
The SELECT trial included over 17,000 adults with heart disease.
Heart protection occurs regardless of weight loss.
Shrinking waist size was linked to better heart outcomes.
Semaglutide reduced heart attack/stroke risk by 20% in people with obesity and heart disease.
- Who
- Researchers studying the SELECT trial.
- What
- Confirmed cardiovascular benefits of semaglutide beyond weight loss.
- When
- The study was published on October 22.
- Where
- The study was conducted, and the results were published in The Lancet.
- Why
- To examine the cardiovascular effects of semaglutide in obese individuals with existing heart disease.
- Drug Name
- Semaglutide
- Trial Name
- SELECT
- Participants
- Over 17,000 adults
- Participants Criteria
- Heart disease and BMI of 27 or higher
- Reduced Risk of Heart Attack/Stroke
- 20%
- Published in
- The Lancet
- Publication Date
- October 22