Archive · 21 Jul 2026
Sonali Bendre's 20-hour fast for autophagy: Experts weigh in
Sonali Bendre, a well-known actor, recently shared that she follows an 18 to 20-hour fast to promote autophagy, which is the body's way of repairing and recycling cells.
This has sparked a lot of interest in extended fasting and its health benefits.
Experts, however, say the science is more complex than it seems.
Autophagy is a natural process where the body breaks down damaged parts and reuses them to keep cells healthy.
While animal studies suggest autophagy can help with healthy aging and protecting against diseases, there isn't strong evidence that a specific duration of fasting triggers it in humans.
Dr. Sanjay Raina, a medical expert, explains that factors like age, genetics, and metabolic health play a role.
Intermittent fasting can still be beneficial for weight management and improving health markers, but very long fasts aren't necessary.
Prolonged fasting can be risky for certain groups, like people with diabetes or eating disorders.
The best approach to long-term health includes regular exercise, good sleep, a balanced diet, and avoiding harmful habits like smoking.
Sonali Bendre follows an 18 to 20-hour fast to promote autophagy.
Autophagy is the body's natural process of cellular repair and recycling.
There is no robust human evidence that a specific duration of fasting triggers autophagy.
Intermittent fasting can benefit weight management and health markers.
Prolonged fasting can be risky for certain groups and should be done under medical supervision.
- Who
- Sonali Bendre, Dr. Sanjay Raina, Yoshinori Ohsumi
- What
- The effectiveness and risks of extended fasting for autophagy.
- When
- Recently, with Sonali Bendre's comments sparking interest.
- Where
- Globally, with specific mention of Amrita Hospital, Faridabad.
- Why
- To understand the health benefits and risks of extended fasting.
Proponents of Extended Fasting
Medical Experts
Effectiveness of Extended Fasting
Proponents of Extended Fasting
Extended fasting, such as 18 to 20 hours, is believed to trigger autophagy, the body's natural process of cellular repair, leading to significant health benefits.
Medical Experts
There is no robust human evidence that identifies a specific duration of fasting at which clinically meaningful autophagy begins. The benefits are more nuanced and depend on various factors.
Suitability for Everyone
Proponents of Extended Fasting
Extended fasting can be beneficial for everyone seeking health improvements.
Medical Experts
Prolonged fasting is not appropriate for some people, including those with diabetes, pregnant or breastfeeding women, frail older adults, underweight individuals, and those with a history of eating disorders.
- Autophagy
- The body’s natural process of cellular repair and recycling.
- Sonali Bendre
- Actor who follows an 18 to 20-hour fast for autophagy.
- Dr. Sanjay Raina
- Head of Internal Medicine at Amrita Hospital, Faridabad.
- Yoshinori Ohsumi
- Japanese cell biologist who received the Nobel Prize in Physiology or Medicine in 2016 for his discoveries relating to autophagy.
- Benefits of Intermittent Fasting
- Body weight, insulin sensitivity, blood pressure, fatty liver disease, and inflammatory markers in overweight people.
- Risks of Prolonged Fasting
- Hypoglycemia, dehydration, muscle loss, fatigue, and nutritional deficiencies.