Archive · 18 Jul 2025
Gene Essential for Vitamin D Absorption May Boost Cancer Treatment
Scientists found a gene called SDR42E1 that helps your body use vitamin D. This gene is important for taking vitamin D from food and using it.
They discovered that if they stopped this gene from working in cancer cells, the cancer cells died.
This suggests that blocking the gene could be a new way to treat cancer, but more research is needed.
A mutation in this gene is also connected to low vitamin D levels in people.
Scientists think this discovery could help treat other diseases where vitamin D is important.
Scientists identified the SDR42E1 gene, essential for vitamin D absorption.
The gene is crucial for taking up and metabolizing vitamin D.
Blocking or inhibiting SDR42E1 may stop cancer cell growth.
A mutation in the SDR42E1 gene is linked to vitamin D deficiency.
Further studies are needed to understand long-term effects.
- Who
- Scientists, including Dr. Georges Nemer and Dr. Nagham Nafiz Hendi.
- What
- Scientists discovered a key gene (SDR42E1) essential for vitamin D absorption which could potentially boost cancer treatment.
- When
- Research was recently published.
- Where
- At the University of College of Health and Life Sciences at Hamad Bin Khalifa University in Qatar, and at Middle East University in Amman, Jordan.
- Why
- To explore new avenues in precision medicine, particularly cancer therapy.
- Gene Name
- SDR42E1
- Function
- Vitamin D absorption and metabolism
- Potential Application
- Cancer therapy
- Effect of Inhibition
- May stop the growth of cancer cells
- Publication
- Frontiers in Endocrinology
- Cancer Cell Type Used
- HCT116 (colorectal cancer)