Archive · 18 Aug 2025
New Signals Predict Chronic Kidney Disease Progression
Scientists are working on a better way to predict how chronic kidney disease will get worse.
They found that measuring certain things in blood and urine can show how sick someone's kidneys are.
One marker, called KIM-1, is a sign of kidney damage; high levels mean the disease might get worse.
This could lead to blood and urine tests that help doctors know which patients are most at risk.
This way, doctors can give patients the right kind of treatment and prevent kidney failure.
This will help doctors better care for people with kidney disease, offering the right level of treatment to prevent serious problems.
Researchers identified biological signals in blood and urine to predict the progression of chronic kidney disease.
Higher levels of KIM-1, a kidney damage marker, correlate with increased risk of mortality and kidney failure.
The study analyzed 21 markers in blood and urine, reflecting kidney disease, inflammation, and heart disease.
The research could lead to more tailored treatment approaches based on individual patient needs.
The study involved 2,581 patients for the KIM-1 analysis and 2,884 patients for the 21 marker analysis.
- Who
- Researchers from The University of Manchester conducted the study.
- What
- Scientists discovered biological signals to predict the progression of chronic kidney disease.
- When
- The research was recently published.
- Where
- The research was conducted in the UK across 16 nephrology centers.
- Why
- To predict the progression of chronic kidney disease, enabling tailored treatments and preventing over-treatment.
- Key Marker
- Kidney Injury Molecule-1 (KIM-1)
- Research Focus
- Blood and urine analysis
- Patient Count (KIM-1 Study)
- 2,581
- Patient Count (21 Marker Study)
- 2,884
- Findings
- KIM-1 levels associated with increased mortality and kidney failure risk.
- Goal
- Tailored treatments for patients
- Published in
- American Journal of Nephrology